Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
about
Etk, a Btk family tyrosine kinase, mediates cellular transformation by linking Src to STAT3 activation.Protein phosphorylation cascades associated with methamphetamine-induced glial activation.The coiled-coil domain of Stat3 is essential for its SH2 domain-mediated receptor binding and subsequent activation induced by epidermal growth factor and interleukin-6The ciliary neurotrophic factor receptor alpha component induces the secretion of and is required for functional responses to cardiotrophin-like cytokineErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent mannerSTAT3 regulates Nemo-like kinase by mediating its interaction with IL-6-stimulated TGFbeta-activated kinase 1 for STAT3 Ser-727 phosphorylationIdentification of both positive and negative domains within the epidermal growth factor receptor COOH-terminal region for signal transducer and activator of transcription (STAT) activationStructural requirements for signal transducer and activator of transcription 3 binding to phosphotyrosine ligands containing the YXXQ motifRequirements for interleukin-4-induced gene expression and functional characterization of Stat6Mutational analysis of the STAT6 SH2 domainCharacterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2RANTES and MIP-1alpha activate stats in T cellsPhosphorylated interferon-alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 proteinThe SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN-alpha signalsCloning and characterization of a specific receptor for mouse oncostatin MPrinciples of interleukin (IL)-6-type cytokine signalling and its regulationStat1 associates with c-kit and is activated in response to stem cell factorInterleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayCrystal structure of a cytokine-binding region of gp130.Inactivation of cardiotrophin-like cytokine, a second ligand for ciliary neurotrophic factor receptor, leads to cold-induced sweating syndrome in a patientKinase-negative mutants of JAK1 can sustain interferon-gamma-inducible gene expression but not an antiviral stateDissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domainCucurbitacins - a promising target for cancer therapySelf-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptorsCiliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesitySTAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylationFunctional subdomains of STAT2 required for preassociation with the alpha interferon receptor and for signalingInteractions between STAT and non-STAT proteins in the interferon-stimulated gene factor 3 transcription complexA single tyrosine of the interleukin-9 (IL-9) receptor is required for STAT activation, antiapoptotic activity, and growth regulation by IL-9The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammatActivation and association of Stat3 with Src in v-Src-transformed cell linesc-Cbl-dependent monoubiquitination and lysosomal degradation of gp130Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptorCholinergic agonists regulate JAK2/STAT3 signaling to suppress endothelial cell activationRecent advances in understanding leptin signaling and leptin resistanceIncreased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinomaThe role of the Janus kinase family/signal transducer and activator of transcription signaling pathway in fibrotic renal diseaseOncogenic role and therapeutic target of leptin signaling in breast cancer and cancer stem cellsThe consequences of selective inhibition of signal transducer and activator of transcription 3 (STAT3) tyrosine705 phosphorylation by phosphopeptide mimetic prodrugs targeting the Src homology 2 (SH2) domain
P2860
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P2860
Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors
description
1995 nî lūn-bûn
@nan
1995 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի մարտին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Choice of STATs and other subs ...... d motifs in cytokine receptors
@ast
Choice of STATs and other subs ...... d motifs in cytokine receptors
@en
Choice of STATs and other subs ...... d motifs in cytokine receptors
@nl
type
label
Choice of STATs and other subs ...... d motifs in cytokine receptors
@ast
Choice of STATs and other subs ...... d motifs in cytokine receptors
@en
Choice of STATs and other subs ...... d motifs in cytokine receptors
@nl
prefLabel
Choice of STATs and other subs ...... d motifs in cytokine receptors
@ast
Choice of STATs and other subs ...... d motifs in cytokine receptors
@en
Choice of STATs and other subs ...... d motifs in cytokine receptors
@nl
P2093
P2860
P3181
P356
P1433
P1476
Choice of STATs and other subs ...... d motifs in cytokine receptors
@en
P2093
G D Yancopoulos
J E Darnell
T G Boulton
T J Farruggella
P2860
P304
P3181
P356
10.1126/SCIENCE.7871433
P407
P577
1995-03-03T00:00:00Z