about
Integrated genetic and epigenetic analysis identifies haplotype-specific methylation in the FTO type 2 diabetes and obesity susceptibility locusThe obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese childrenFTO Obesity Variant Circuitry and Adipocyte Browning in HumansN6-methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTOALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertilityHuman AlkB homologue 1 (ABH1) exhibits DNA lyase activity at abasic sitesThe bigger picture of FTO: the first GWAS-identified obesity geneComprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codonsPolar and brown bear genomes reveal ancient admixture and demographic footprints of past climate changeA commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderlyThe AlkB domain of mammalian ABH8 catalyzes hydroxylation of 5-methoxycarbonylmethyluridine at the wobble position of tRNAHypothalamic FTO is associated with the regulation of energy intake not feeding rewardLong-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3Recent advances in dynamic m6A RNA modificationThe second decade of 3C technologies: detailed insights into nuclear organizationRole of FTO in Adipocyte Development and Function: Recent InsightsObesity genetics in mouse and human: back and forth, and back againTranscriptional enhancers: functional insights and role in human diseaseIn utero programming of later adiposity: the role of fetal growth restrictionThe complex interplay of genetic and lifestyle risk factors in type 2 diabetes: an overviewStructure and function of dioxygenases in histone demethylation and DNA/RNA demethylationFat: an evolving issueN6-methyl-adenosine modification in messenger and long non-coding RNAMinireview: The link between fat and bone: does mass beget mass?Genetic and epigenetic control of metabolic healthLoss of FTO antagonises Wnt signaling and leads to developmental defects associated with ciliopathiesAdult onset global loss of the fto gene alters body composition and metabolism in the mouseImplications for Damage Recognition during Dpo4-Mediated Mutagenic Bypass of m1G and m3C LesionsSwitching demethylation activities between AlkB family RNA/DNA demethylases through exchange of active-site residuesModify or die?--RNA modification defects in metazoansObesity-associated variants within FTO form long-range functional connections with IRX3Scrutinizing the FTO locus: compelling evidence for a complex, long-range regulatory contextA preliminary association study of fat mass and obesity associated gene polymorphisms and degenerative disc disease in a Chinese Han populationInhibition of 2-oxoglutarate dependent oxygenasesA mouse model for the metabolic effects of the human fat mass and obesity associated FTO geneCommon variants of FTO are associated with childhood obesity in a cross-sectional study of 3,126 urban Indian childrenImportant Role of FTO in the Survival of Rare Panresistant Triple-Negative Inflammatory Breast Cancer Cells Facing a Severe Metabolic ChallengeMutation of SLC35D3 causes metabolic syndrome by impairing dopamine signaling in striatal D1 neuronsThe effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approachGenome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts
P2860
Q21136048-6DC9C99D-7015-490C-8FD8-9FEFB93243E4Q21261510-4DDB0456-E7F4-42B1-AD89-5722D7712D91Q22305008-87B13879-AB8C-43F1-B1DD-DF436F34FAC6Q24293481-88D19808-5C96-476D-9D85-9C8B4EE5B7D4Q24304362-99662DA0-8373-4657-8C83-E9B1F36A1244Q24328781-D2930812-1AE1-4319-B2F1-505261191424Q24562954-14111673-A936-47C0-A2A9-A91D1CD7C850Q24598126-810A8EAE-7B21-4AB9-A15E-B65A8967CFA6Q24603841-302EB3E8-94E0-4CBF-981D-C6C38192ECC6Q24631142-18BFEED7-0DE1-4699-AD6E-721A1F6FA47BQ24633817-5B1EFB8D-C83E-46B6-943B-14B4E8F2C38CQ24643901-3077F065-3E99-47C4-982F-32744A393AC6Q24651249-02F87509-6184-42FA-B4F0-EC5E5EAADB0FQ26744188-4B5D4217-3C14-4159-9E76-461CBC20A23FQ26747370-410B8056-8D77-4BBB-B849-BCC6E864417AQ26770844-3042758A-1CCB-4120-95C9-AA7AD1CB4CA7Q26782027-31C25326-3FB1-4B2C-9CFB-778BD3AE570AQ26782507-4F600002-36DE-4059-A8A6-3FF7A3E7DF4DQ26996520-330669A2-3DC4-4FA0-98C3-24F622B3969BQ26997813-A7B7CAC3-BF7C-427D-AC34-B8FAAC259F03Q27012506-5272798F-51D1-46F1-9987-37BCD08C45E9Q27013025-64D92027-6580-4592-BB5B-56FED25111D8Q27022522-6BE7A570-313B-45A9-82A0-236EE79EB11DQ27026223-94682BB7-D29D-4737-9F35-5F924C0FBDE6Q27026287-421011DA-5527-46A3-AB0C-00E01E6AA5C4Q27324215-A4935E9F-F70E-4EAB-AEFB-B1315124F708Q27325807-47F6BE5B-B00C-4917-A17F-47A8E5DBE8CEQ27668173-DB8D186C-143A-4C60-986F-7E5229DCBECBQ27689434-60C39E66-94BF-4732-89CB-FDE8CAA7B9AEQ28087742-4002CE31-CA57-4EA0-A490-46F5F981948AQ28236283-AC500D7B-AFAD-4C34-BA2E-F7C9D371AED8Q28266971-83AB3A38-ED43-4D2A-A235-7DDD42F2D98EQ28303330-F242BAB2-5D48-4168-9362-CD658A5C90DBQ28306956-6AC517AE-9F13-4E4C-A15A-7E552E0DDCD2Q28475923-D46C7790-68A8-49DF-B48B-2DAD3C83E143Q28484424-C77C58E8-07B5-4128-8B84-B69C7CACC898Q28552551-417598F5-A3E3-47C4-A6FA-E7424798A2A1Q28593543-A3C4D91B-543A-4EC5-8CB6-F362A657A522Q28730188-DFF733A0-8C37-4EA2-97FB-A7AEBB710678Q28730852-B4606BFC-2D61-4B9F-A6EE-08B9FCCEAC33
P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Inactivation of the Fto gene protects from obesity
@ast
Inactivation of the Fto gene protects from obesity
@en
Inactivation of the Fto gene protects from obesity
@nl
type
label
Inactivation of the Fto gene protects from obesity
@ast
Inactivation of the Fto gene protects from obesity
@en
Inactivation of the Fto gene protects from obesity
@nl
prefLabel
Inactivation of the Fto gene protects from obesity
@ast
Inactivation of the Fto gene protects from obesity
@en
Inactivation of the Fto gene protects from obesity
@nl
P2093
P3181
P356
P1433
P1476
Inactivation of the Fto gene protects from obesity
@en
P2093
Christian Emmerling
Jeanette Vierkotten
Julia Fischer
Thomas Peters
Ulrich Rüther
P2888
P3181
P356
10.1038/NATURE07848
P407
P577
2009-04-16T00:00:00Z
P5875
P6179
1046426350