about
Inactivation of the Fto gene protects from obesityNew Endocrine Society guidelines for hyperprolactinemia-piecing together the pituitary puzzle.Targeted deletion of somatotroph insulin-like growth factor-I signaling in a cell-specific knockout mouse modelThe fat mass and obesity associated gene (Fto) regulates activity of the dopaminergic midbrain circuitry.Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity.gp130 signaling in proopiomelanocortin neurons mediates the acute anorectic response to centrally applied ciliary neurotrophic factor.Metagenomics: Shaping the gut microbiome.Central insulin action regulates peripheral glucose and fat metabolism in mice.Autocrine IGF-1 action in adipocytes controls systemic IGF-1 concentrations and growthEpidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation.Nutrition: High isoflavone intake delays puberty onset and may reduce breast cancer risk in girls.Citalopram for hot flashes.Therapy: Propylthiouracil use associated with severe hepatotoxicity in children.Cancer: Long-term use of metformin could protect against breast cancer.Lipids: Eprotirome shows promise as a novel way to target dyslipidemia.Obesity: microRNA-dependent control of MODY gene expression contributes to obesity-associated insulin resistance.Inflammation: Intestinal-type alkaline phosphatase--a new therapeutic weapon?Diabetes: individualized HbA(1c) targets in elderly patients with T2DM.Cancer: polymorphisms in detoxification genes increase HMTC risk and match tumour phenotype.Nutrition: Risk of T1DM increases with early and late weaning.Growth hormone in health and disease: Consensus guidelines for GH therapy in Prader-Willi syndrome--this way forward?Obesity: Teaching an old drug new tricks--amlexanox targets inflammation to improve metabolic dysfunction.Basic research: new metformin mechanism elucidated in vitro and in vivo.Surgery: T2DM remission after RYGB-a 'gutsy' move.Growth hormone in health and disease: Novel ghrelin mimetic is safe and effective as a GH stimulation test.Pharmacotherapy: Small-molecule disruptors of glucokinase inhibition.Technology: Let there be light: new implantable hydrogels for in vivo optical sensing and therapy.Paediatrics: Circulating microRNAs-predictors of obesity?Obesity: Behavioural weight-loss intervention in high-risk patients.Therapy: raising BMD-two drugs are better than one.Reproductive endocrinology: BMPR-2 signalling is essential for maintenance of pregnancy.Obesity: Hsp60 integrates central crosstalk.Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease.Neuroendocrinology: Mitofusins and energy balance.Reproductive endocrinology: macrosomia in developing countries.Nutrition: New diabetes nutrition recommendations--food for thought.Lipids: Gut-derived lipid signal links dopamine deficiency and high-fat feeding.Childhood weight gain increases risk of thyroid disorders.Genetics: genotype determines weight loss after bariatric surgery.Obesity: Weight gain prevention.
P50
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P50
description
hulumtuese
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Linda Koch
@ast
Linda Koch
@en
Linda Koch
@es
Linda Koch
@nl
Linda Koch
@sl
type
label
Linda Koch
@ast
Linda Koch
@en
Linda Koch
@es
Linda Koch
@nl
Linda Koch
@sl
prefLabel
Linda Koch
@ast
Linda Koch
@en
Linda Koch
@es
Linda Koch
@nl
Linda Koch
@sl
P106
P21
P31
P496
0000-0002-2943-1993