Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer
about
Loss of CHFR in human mammary epithelial cells causes genomic instability by disrupting the mitotic spindle assembly checkpointPredictive value of CHFR and MLH1 methylation in human gastric cancer.Helicobacter pylori infection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis.The anti-proliferative effects of the CHFR depend on the forkhead associated domain, but not E3 ligase activity mediated by ring finger domain.Hypermethylation and aberrant expression of Wnt antagonist secreted frizzled-related protein 1 in gastric cancerMethylation-mediated gene silencing as biomarkers of gastric cancer: a review.Aberrant promoter methylation of caveolin-1 is associated with favorable response to taxane-platinum combination chemotherapy in advanced NSCLCRNF8-dependent histone ubiquitination during DNA damage response and spermatogenesisRegulation of the DNA damage response by ubiquitin conjugation.The auto-ubiquitylation of E3 ubiquitin-protein ligase Chfr at G2 phase is required for accumulation of polo-like kinase 1 and mitotic entry in mammalian cells.Sirt7 promotes gastric cancer growth and inhibits apoptosis by epigenetically inhibiting miR-34a.Endometrial Cancer and Hypermethylation: Regulation of DNA and MicroRNA by EpigeneticsCHFR protein regulates mitotic checkpoint by targeting PARP-1 protein for ubiquitination and degradation.Small molecule inhibition of the CHFR-PARP1 interaction as novel approach to overcome intrinsic taxane resistance in cancerBeyond Field Effect: Analysis of Shrunken Centroids in Normal Esophageal Epithelia Detects Concomitant Esophageal Adenocarcinoma.CHFR protein expression predicts outcomes to taxane-based first line therapy in metastatic NSCLC.Cytoplasmic RASSF2A is a proapoptotic mediator whose expression is epigenetically silenced in gastric cancerCHFR: A Novel Mitotic Checkpoint Protein and Regulator of Tumorigenesis.Checkpoint with forkhead-associated and ring finger promoter hypermethylation correlates with microsatellite instability in gastric cancer.CHFR silencing or microsatellite instability is associated with increased antitumor activity of docetaxel or gemcitabine in colorectal cancer.Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice.Enhanced genomic instabilities caused by deregulated microtubule dynamics and chromosome segregation: a perspective from genetic studies in mice.Emerging evidence for CHFR as a cancer biomarker: from tumor biology to precision medicine.Epigenetic alterations in gastric cancer (Review).Integrated analysis of DNA methylation and mRNA expression profiling reveals candidate genes associated with cisplatin resistance in non-small cell lung cancerCharacterizing DNA methylation patterns in pancreatic cancer genome.Prognostic value of excision repair cross-complementation group 1 expression in gastric cancer: A meta-analysis.Association between CHFR gene hypermethylation and gastric cancer risk: a meta-analysisCancer DNA methylation: molecular mechanisms and clinical implications.Clinicopathological significance of CHFR methylation in non-small cell lung cancer: a systematic review and meta-analysis.The inhibition of UBC13 expression and blockage of the DNMT1-CHFR-Aurora A pathway contribute to paclitaxel resistance in ovarian cancer.Clinicopathological significance of CHFR promoter methylation in gastric cancer: a meta-analysis.Epigenetic Modifications as Biomarkers of Tumor Development, Therapy Response, and Recurrence across the Cancer Care Continuum.
P2860
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P2860
Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer
description
2003 nî lūn-bûn
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2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
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2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@ast
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@en
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@nl
type
label
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@ast
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@en
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@nl
prefLabel
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@ast
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@en
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@nl
P2093
P1433
P1476
Epigenetic inactivation of CHF ...... e inhibitors in gastric cancer
@en
P2093
Ayumi Satoh
Fumio Itoh
Hiroaki Mita
Hiromu Suzuki
Kazuhiro Ogi
Kohzoh Imai
Masahiro Fujita
Masanobu Kusano
Masao Hosokawa
Minoru Toyota
P304
P407
P50
P577
2003-12-01T00:00:00Z