Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
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Genetics of type 1 diabetesProtein tyrosine phosphatase PTPN22 in human autoimmunityHigh basal activity of the PTPN22 gain-of-function variant blunts leukocyte responsiveness negatively affecting IL-10 production in ANCA vasculitisPTPN22 R620W polymorphism and ANCA disease risk in white populations: a metaanalysisrs2476601 T allele (R620W) defines high-risk PTPN22 type I diabetes-associated haplotypes with preliminary evidence for an additional protective haplotype.Susceptibility to type 1 diabetes conferred by the PTPN22 C1858T polymorphism in the Spanish population.Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice.Early prediction of autoimmune (type 1) diabetes.Lymphoid tyrosine phosphatase and autoimmunity: human genetics rediscovers tyrosine phosphatases.Familial type 1 diabetes mellitus - gender distribution and age at onset of diabetes distinguish between parent-offspring and sib-pair subgroupsWhy is PTPN22 a good candidate susceptibility gene for autoimmune disease?PTPN22 genetic variation: evidence for multiple variants associated with rheumatoid arthritisAssociation of PTPN22 1858T/T genotype with type 1 diabetes, Graves' disease but not with rheumatoid arthritis in Russian population.Targeting the PTPome in human disease.Functional single nucleotide polymorphism-based association studies.Replication and further characterization of a Type 1 diabetes-associated locus at the telomeric end of the major histocompatibility complexImportant genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats.Extreme genetic risk for type 1A diabetes in the post-genome eraGenetic polymorphisms in PTPN22, PADI-4, and CTLA-4 and risk for rheumatoid arthritis in two longitudinal cohort studies: evidence of gene-environment interactions with heavy cigarette smoking.Stem cell-based therapy for the treatment of Type 1 diabetes mellitus.Genes mediating environment interactions in type 1 diabetes.Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms.Biomarkers for type 1 diabetes.The role of PTPN22 C1858T gene polymorphism in diabetes mellitus type 1: first evaluation in Greek children and adolescentsFrom markers to molecular mechanisms: type 1 diabetes in the post-GWAS era.IFIH1 polymorphisms are significantly associated with type 1 diabetes and IFIH1 gene expression in peripheral blood mononuclear cells.The R620W polymorphism of the protein tyrosine phosphatase 22 gene in autoimmune thyroid diseases and rheumatoid arthritis in the Tunisian population.No evidence for association of PTPN22 R620W functional variant C1858T with type 1 diabetes in Asian Indians.Allele and haplotype frequency distribution in PTPN22 gene across variable ethnic groups: Implications for genetic association studies for autoimmune diseases.The PTPN22gain-of-function+1858T(+) genotypes correlate with low IL-2 expression in thymomas and predispose to myasthenia gravis.A novel single nucleotide polymorphism in the protein tyrosine phosphatase N22 gene (PTPN22) is associated with Type 1 diabetes in a Chinese population.Finnish case-control and family studies support PTPN22 R620W polymorphism as a risk factor in rheumatoid arthritis, but suggest only minimal or no effect in juvenile idiopathic arthritis.Serum titres of anti-glutamic acid decarboxylase-65 and anti-IA-2 autoantibodies are associated with different immunoregulatory milieu in newly diagnosed type 1 diabetes patients.PTPN22 C1858T polymorphism in Colombian patients with autoimmune diseases.The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis.Sex-specific association of the human PTPN22 1858T-allele with type 1 diabetes.On type 1 diabetes mellitus pathogenesis.PTPN22 gene polymorphism (C1858T) is associated with susceptibility to type 1 diabetes: a meta-analysis of 19,495 cases and 25,341 controls.Association of protein tyrosine phosphatase non-receptor type 22 gene functional variant C1858T, HLA-DQ/DR genotypes and autoantibodies with susceptibility to type-1 diabetes mellitus in Kuwaiti Arabs.Genetics of type 1 diabetes
P2860
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P2860
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
description
2005 nî lūn-bûn
@nan
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@ast
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@en
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@nl
type
label
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@ast
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@en
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@nl
prefLabel
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@ast
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@en
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@nl
P1433
P1476
Genetic association between a lymphoid tyrosine phosphatase (PTPN22) and type 1 diabetes
@en
P2093
Jin-Xiong She
Weipeng Zheng
P356
10.2337/DIABETES.54.3.906
P407
P577
2005-03-01T00:00:00Z