Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor - Wikidata - awgldk - TriplyDB

Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor

Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor

http://www.wikidata.org/entity/Q28238303

about

Function, regulation and pathological roles of the Gab/DOS docking proteins Group I and II mammalian PAKs have different modes of activation by Cdc42 Signaling, Regulation, and Specificity of the Type II p21-activated Kinases MicroRNA-433 inhibits cell proliferation in hepatocellular carcinoma by targeting p21 activated kinase (PAK4)microRNA-126 suppresses PAK4 expression in ovarian cancer SKOV3 cells p21-Activated kinase 4 promotes prostate cancer progression through CREB PAK as a therapeutic target in gastric cancer PAK4: a pluripotent kinase that regulates prostate cancer cell adhesion.PAK4 kinase-mediated SCG10 phosphorylation involved in gastric cancer metastasis The signaling adaptor GAB1 regulates cell polarity by acting as a PAR protein scaffold.PAK4 interacts with p85 alpha: implications for pancreatic cancer cell migration Cdc42 regulates apical junction formation in human bronchial epithelial cells through PAK4 and Par6B P21-activated kinase 4 involves TSH induced papillary thyroid cancer cell proliferation.MET aberrations and c-MET inhibitors in patients with gastric and esophageal cancers in a phase I unit.p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes.Maternal pak4 expression is required for primitive myelopoiesis in zebrafish The protein kinase Pak4 disrupts mammary acinar architecture and promotes mammary tumorigenesis.Republished: tracing PAKs from GI inflammation to cancer Rho GTPases and regulation of cell migration and polarization in human corneal epithelial cells.The Cdc42 Effector Kinase PAK4 Localizes to Cell-Cell Junctions and Contributes to Establishing Cell Polarity.PAK4 confers the malignance of cervical cancers and contributes to the cisplatin-resistance in cervical cancer cells via PI3K/AKT pathway.Functional cooperativity by direct interaction between PAK4 and MMP-2 in the regulation of anoikis resistance, migration and invasion in glioma Systems-wide analysis of K-Ras, Cdc42, and PAK4 signaling by quantitative phosphoproteomics.Novel role for p21-activated kinase 2 in thrombin-induced monocyte migration.MET abnormalities in patients with genitourinary malignancies and outcomes with c-MET inhibitors.What's in a loop?P21 activated kinases: structure, regulation, and functions.Tracing PAKs from GI inflammation to cancer.Repositioning Potential of PAK4 to Osteoclastic Bone Resorption.Structure, biochemistry, and biology of PAK kinases.miR-224 promotion of cell migration and invasion by targeting Homeobox D 10 gene in human hepatocellular carcinoma.PAK4 kinase activity and somatic mutation promote carcinoma cell motility and influence inhibitor sensitivity.PAK family kinases: Physiological roles and regulation.PAK4-6 in cancer and neuronal development.Novel role of proline-rich nonreceptor tyrosine kinase 2 in vascular wall remodeling after balloon injury PAK4 confers cisplatin resistance in gastric cancer cells via PI3K/Akt- and MEK/ERK-dependent pathways The pak4 protein kinase in breast cancer.GGA3 functions as a switch to promote Met receptor recycling, essential for sustained ERK and cell migration.A novel interaction of PAK4 with PPARγ to regulate Nox1 and radiation-induced epithelial-to-mesenchymal transition in glioma.Inhibition of neuroblastoma proliferation by PF-3758309, a small-molecule inhibitor that targets p21-activated kinase 4.

P2860

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P2860

Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor

http://www.wikidata.org/entity/Q28238303

description

2009 nî lūn-bûn

@nan

2009 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

@ast

Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

@en

Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

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type

label

Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

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Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

@en

Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

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prefLabel

Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

@ast

Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

@en

Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

@nl

P1433

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P2860

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P932

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P1433

Molecular and Cellular Biology

P1476

Pak4, a novel Gab1 binding par ...... d invasion by the Met receptor

@en

P2093

Grigorios N Paliouras

http://www.w3.org/2001/XMLSchema#string

Monica A Naujokas

http://www.w3.org/2001/XMLSchema#string

Morag Park

http://www.w3.org/2001/XMLSchema#string

P2860

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

Activation of LIM-kinase by Pak1 couples Rac/Cdc42 GTPase signalling to actin cytoskeletal dynamics

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

A Grb2-associated docking protein in EGF- and insulin-receptor signalling

The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase

P21-activated kinase 4 interacts with integrin alpha v beta 5 and regulates alpha v beta 5-mediated cell migration

A generic protein purification method for protein complex characterization and proteome exploration

Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesis

Signaling of hepatocyte growth factor/scatter factor (HGF) to the small GTPase Rap1 via the large docking protein Gab1 and the adapter protein CRKL

Pak to the future

P304

3018-32

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scholarly article

P356

10.1128/MCB.01286-08

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P407

P433

11

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P478

29

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P577

2009-06-01T00:00:00Z

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P5875

24203885

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P698

19289496

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P932

2682017

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