Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
about
Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinasesMicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3The cyclin-like protein, SPY1, regulates the ERα and ERK1/2 pathways promoting tamoxifen resistance.Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1.The receptor tyrosine kinase FGFR4 negatively regulates NF-kappaB signaling.The cyclin-like protein Spy1/RINGO promotes mammary transformation and is elevated in human breast cancerSpy1 Protein Mediates Phosphorylation and Degradation of SCG10 Protein in Axonal Degeneration.Apoptosis and the target genes of microRNA-21.Targeting prostate cancer based on signal transduction and cell cycle pathways.The atypical CDK activator Spy1 regulates the intrinsic DNA damage response and is dependent upon p53 to inhibit apoptosis.Spy1 participates in the proliferation and apoptosis of epithelial ovarian cancer.Cell adhesion to fibronectin down-regulates the expression of Spy1 and contributes to drug resistance in multiple myeloma cells.Spy1 is frequently overexpressed in malignant gliomas and critically regulates the proliferation of glioma cells.The cyclin-dependent kinase activator, Spy1A, is targeted for degradation by the ubiquitin ligase NEDD4.Direct interactions with both p27 and Cdk2 regulate Spy1-mediated proliferation in vivo and in vitro.Structural basis of divergent cyclin-dependent kinase activation by Spy1/RINGO proteins.The atypical cell cycle regulator Spy1 suppresses differentiation of the neuroblastoma stem cell population.Temporal-spatial expressions of Spy1 in rat sciatic nerve after crush.Expression of Spy1 protein in human non-Hodgkin's lymphomas is correlated with phosphorylation of p27 Kip1 on Thr187 and cell proliferation.Peripheral nerve lesion induces an up-regulation of Spy1 in rat spinal cord.High Spy1 expression predicts poor prognosis in colorectal cancer
P2860
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P2860
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@ast
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@en
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@nl
type
label
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@ast
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@en
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@nl
prefLabel
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@ast
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@en
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@nl
P2093
P356
P1433
P1476
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27
@en
P2093
April N Meyer
Christopher W McAndrew
Daniel J Donoghue
Lisa A Porter
Randy F Gastwirt
P304
P356
10.4161/CC.6.15.4520
P407
P577
2007-08-01T00:00:00Z