Comparative study of action mechanisms of dimebon and memantine on AMPA- and NMDA-subtypes glutamate receptors in rat cerebral neurons
about
Evaluation of Dimebon in cellular model of Huntington's diseaseTranslatability scoring in drug development: eight case studiesNovel therapeutics for Alzheimer's disease: an updateCombotherapy and current concepts as well as future strategies for the treatment of Alzheimer's diseaseTargeting the prodromal stage of Alzheimer's disease: bioenergetic and mitochondrial opportunitiesAcute dosing of latrepirdine (Dimebon), a possible Alzheimer therapeutic, elevates extracellular amyloid-beta levels in vitro and in vivoMitochondrial Drugs for Alzheimer Disease.Current treatment and recent clinical research in Alzheimer's diseaseThe rise and fall of Dimebon.Neuroprotective strategies involving ROS in Alzheimer disease.Mitochondria and antioxidant targeted therapeutic strategies for Alzheimer's disease.Alzheimer's disease and age-related memory decline (preclinical)The acute effects of dimebolin, a potential Alzheimer's disease treatment, on working memory in rhesus monkeysLatrepirdine, a potential novel treatment for Alzheimer's disease and Huntington's chorea.Dimebon slows progression of proteinopathy in γ-synuclein transgenic mice.Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer DiseaseDimebon alters hippocampal amyloid pathology in 3xTg-AD mice.Latrepirdine stimulates autophagy and reduces accumulation of α-synuclein in cells and in mouse brain.NMDA receptors in clinical neurology: excitatory times ahead.Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model.Target- and mechanism-based therapeutics for neurodegenerative diseases: strength in numbersNeuronal calcium mishandling and the pathogenesis of Alzheimer's diseaseThe prevention and treatment of cognitive decline and dementia: An overview of recent research on experimental treatments.Polycyclic compounds: ideal drug scaffolds for the design of multiple mechanism drugs?Mitochondria: a therapeutic target in neurodegenerationNeuronal calcium signaling, mitochondrial dysfunction, and Alzheimer's disease.Dimebolin in dementia.Antioxidant approaches for the treatment of Alzheimer's disease.5-hydroxytryptamine subtype 6 receptor modulators: a patent survey.Novel N-methyl-D-aspartate receptor antagonists: a review of compounds patented since 2006.Can small molecules provide truly effective enhancement of cognition? Current achievements and future directions.Pharmacologic approaches to the treatment of Huntington's disease.5HT(6) receptor antagonists: a patent update. Part 1. Sulfonyl derivatives.Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseasesNovel Sites of Neuroprotective Action of Dimebon (Latrepirdine).A Review of Pharmacological Treatments for Depression in Alzheimer's Disease.Corticostriatal circuit dysfunction in Huntington's disease: intersection of glutamate, dopamine and calcium.Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice.Dimebon disappointment.Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.
P2860
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P2860
Comparative study of action mechanisms of dimebon and memantine on AMPA- and NMDA-subtypes glutamate receptors in rat cerebral neurons
description
2003 nî lūn-bûn
@nan
2003 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Comparative study of action me ...... eptors in rat cerebral neurons
@ast
Comparative study of action me ...... eptors in rat cerebral neurons
@en
Comparative study of action me ...... eptors in rat cerebral neurons
@nl
type
label
Comparative study of action me ...... eptors in rat cerebral neurons
@ast
Comparative study of action me ...... eptors in rat cerebral neurons
@en
Comparative study of action me ...... eptors in rat cerebral neurons
@nl
prefLabel
Comparative study of action me ...... eptors in rat cerebral neurons
@ast
Comparative study of action me ...... eptors in rat cerebral neurons
@en
Comparative study of action me ...... eptors in rat cerebral neurons
@nl
P2093
P1476
Comparative study of action me ...... eptors in rat cerebral neurons
@en
P2093
O A Dranyi
S O Bachurin
V V Grigorev
P356
10.1023/B:BEBM.0000017097.75818.14
P407
P577
2003-11-01T00:00:00Z
P6179
1004471795