Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.
about
The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular LocationsInterplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motilityANKRD26 and its interacting partners TRIO, GPS2, HMMR and DIPA regulate adipogenesis in 3T3-L1 cellsYeast Augmented Network Analysis (YANA): a new systems approach to identify therapeutic targets for human genetic diseasesBuilding risk-on-a-chip models to improve breast cancer risk assessment and prevention.RHAMM deficiency disrupts folliculogenesis resulting in female hypofertility.The cytoskeletal protein RHAMM and ERK1/2 activity maintain the pluripotency of murine embryonic stem cells.Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset.Bioinformatic description of immunotherapy targets for pediatric T-cell leukemia and the impact of normal gene sets used for comparison.Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability.BRCA1 controls the cell division axis and governs ploidy and phenotype in human mammary cells.A case of cervical cancer expressed three mRNA variant of Hyaluronan-mediated motility receptor.Spatial regulation of Aurora A activity during mitotic spindle assembly requires RHAMM to correctly localize TPX2The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.TPX2 impacts acetylation of histone H4 at lysine 16: implications for DNA damage response.Uncovering the dual role of RHAMM as an HA receptor and a regulator of CD44 expression in RHAMM-expressing mesenchymal progenitor cells.Aurora A kinase (AURKA) in normal and pathological cell division.Prognostic significance of CD168 overexpression in colorectal cancerGlobal nutrition research: nutrition and breast cancer prevention as a model.Deregulation of hyaluronan synthesis, degradation and binding promotes breast cancer.Therapeutic targeting of hyaluronan in the tumor stroma.Edgotype: a fundamental link between genotype and phenotype.TPX2: of spindle assembly, DNA damage response, and cancer.Role of receptor for hyaluronan-mediated motility (RHAMM) in human head and neck cancers.Hyaluronan and RHAMM in wound repair and the "cancerization" of stromal tissues.HMMR antisense RNA 1, a novel long noncoding RNA, regulates the progression of basal-like breast cancer cellsCarcinoma Cell Hyaluronan as a "Portable" Cancerized Prometastatic Microenvironment.Overexpression of Specific CD44 Isoforms Is Associated with Aggressive Cell Features in Acquired Endocrine Resistance.Cell Polarity Proteins in Breast Cancer Progression.Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition.Targeting protein for xenopus kinesin-like protein 2 (TPX2) regulates γ-histone 2AX (γ-H2AX) levels upon ionizing radiation.The hyaluronan-mediated motility receptor RHAMM promotes growth, invasiveness and dissemination of colorectal cancer.Human hyaluronic acid synthase-1 promotes malignant transformation via epithelial-to-mesenchymal transition, micronucleation and centrosome abnormalities.HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development.The non-motor adaptor HMMR dampens Eg5-mediated forces to preserve the kinetics and integrity of chromosome segregation.Functional genomics identifies specific vulnerabilities in PTEN-deficient breast cancer.Tubers from patients with tuberous sclerosis complex are characterized by changes in microtubule biology through ROCK2 signalling.
P2860
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P2860
Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.
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2011 nî lūn-bûn
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2011 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@ast
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@en
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@nl
type
label
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@ast
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@en
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@nl
prefLabel
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@ast
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@en
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@nl
P2093
P2860
P50
P1433
P1476
Interplay between BRCA1 and RH ...... fluence risk of breast cancer.
@en
P2093
Alberto Villanueva
Alexander Miron
Andrew K Godwin
Anna Allavena
Anna Petit
Anna von Wachenfeldt
Antoine de Pauw
Barbara L Weber
Bella Kaufman
P2860
P304
P356
10.1371/JOURNAL.PBIO.1001199
P407
P50
P577
2011-11-15T00:00:00Z