Genomic organization of the X-linked gene (PIG-A) that is mutated in paroxysmal nocturnal haemoglobinuria and of a related autosomal pseudogene mapped to 12q21
about
The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG-A, PIG-H, PIG-C and GPI1.PIG-A mutations in paroxysmal nocturnal hemoglobinuria and in normal hematopoiesisGPI1 stabilizes an enzyme essential in the first step of glycosylphosphatidylinositol biosynthesisBiosynthesis of glycosylphosphatidylinositols in mammals and unicellular microbes.Paroxysmal nocturnal haemoglobinuria: nature's gene therapy?Paroxysmal nocturnal hemoglobinuriaThe frequency of granulocytes with spontaneous somatic mutations: a wide distribution in a normal human populationComplement-mediated haemolysis and the role of blood transfusion in paroxysmal nocturnal haemoglobinuria.X inactivation and somatic cell selection rescue female mice carrying a Piga-null mutation.Murine embryonic stem cells without pig-a gene activity are competent for hematopoiesis with the PNH phenotype but not for clonal expansion.Silencing of genes required for glycosylphosphatidylinositol anchor biosynthesis in Burkitt lymphoma.Development of an in vitro PIG-A gene mutation assay in human cells.Molecular Pathogenesis of Paroxysmal Nocturnal Hemoglobinuria.Characterization and genomic mapping of the ZNF80 locus: expression of this zinc-finger gene is driven by a solitary LTR of ERV9 endogenous retroviral family.Antibody selection against CD52 produces a paroxysmal nocturnal haemoglobinuria phenotype in human lymphocytes by a novel mechanismParoxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents.Decreased prion protein expression in human peripheral blood leucocytes from patients with paroxysmal nocturnal haemoglobinuria.Chimaeric mice with disruption of the gene coding for phosphatidylinositol glycan class A (Pig-a) were defective in embryogenesis and spermatogenesis.
P2860
Q24533042-6BD1229D-FF60-4220-A6AE-3D11F3082BF6Q28259136-CCBA1FED-C87E-4CA2-B1F6-F2A14CC54717Q28586610-835C9142-8A8F-4FD3-819C-BDB9BFAA3D3EQ33672095-B20B4370-313C-49AD-92C9-847B7C281C7BQ33918976-EE842ACF-8744-4BFE-960C-70A4C4F31F3DQ34431429-47C8D516-0BDA-4009-BFB9-14F6B6E80F02Q34559073-3CD63000-DA57-48CB-A07D-BED77B5E3E9AQ36187306-F7940941-6220-47FA-82D2-00597633F586Q36397379-490AC522-E375-4DC6-9E59-26CA619707E9Q37371566-4C6D0467-EBD2-47C7-B635-6E7C92597410Q37390398-08EC3075-4E4F-4A1A-897F-1B12B24C2020Q38722763-68AD660B-3DF1-4CC6-9B74-C000F84578DBQ38894040-8F408889-4278-4531-B607-0C5B6A4A6B7DQ40395101-06BF1871-9A6E-4E0A-A5C4-497D8A9AA075Q41120639-DF528C7C-0DF8-45DB-8624-7623AC3963ADQ42036462-2FEDAAA6-4363-4910-8F3E-8210985E2DDCQ43548662-C8486D37-6DF1-497C-9376-5C8EA76010A2Q52541054-5371C95E-C482-4169-A7D2-313105984D4D
P2860
Genomic organization of the X-linked gene (PIG-A) that is mutated in paroxysmal nocturnal haemoglobinuria and of a related autosomal pseudogene mapped to 12q21
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@ast
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@en
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@nl
type
label
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@ast
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@en
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@nl
prefLabel
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@ast
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@en
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@nl
P2093
P356
P1476
Genomic organization of the X- ...... mal pseudogene mapped to 12q21
@en
P2093
P356
10.1093/HMG/3.5.751
P407
P577
1994-05-01T00:00:00Z