The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3
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A structure filter for the Eukaryotic Linear Motif Resource.The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complexBinding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decayThe structure of the ASAP core complex reveals the existence of a Pinin-containing PSAP complexAn unusual arrangement of two 14-3-3-like domains in the SMG5-SMG7 heterodimer is required for efficient nonsense-mediated mRNA decayFunctions of hUpf3a and hUpf3b in nonsense-mediated mRNA decay and translationUnusual bipartite mode of interaction between the nonsense-mediated decay factors, UPF1 and UPF2Mutations in UPF3B, a member of the nonsense-mediated mRNA decay complex, cause syndromic and nonsyndromic mental retardationELM: the status of the 2010 eukaryotic linear motif resourceU2AF homology motifs: protein recognition in the RRM worldSplicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex componentsUsing the cre-lox recombination system to assess functional impairment caused by amino acid substitutions in yeast proteinsNonsense-mediated mRNA decay: novel mechanistic insights and biological impactRan-dependent nuclear export mediators: a structural perspectiveProteins involved in the degradation of cytoplasmic mRNA in the major eukaryotic model systemsNonsense-mediated mRNA decay: inter-individual variability and human diseaseStructure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunitStructure of the central RNA recognition motif of human TIA-1 at 1.95Å resolutionThe RRM domain in GW182 proteins contributes to miRNA-mediated gene silencingRaver1 Interactions with Vinculin and RNA Suggest a Feed-Forward Pathway in Directing mRNA to Focal AdhesionsInsights into the recruitment of the NMD machinery from the crystal structure of a core EJC-UPF3b complexNovel protein-protein contacts facilitate mRNA 3'-processing signal recognition by Rna15 and Hrp1Nuclear Magnetic Resonance Solution Structure of the Peptidoglycan-Binding SPOR Domain from Escherichia coli DamX: Insights into Septal LocalizationStructure and RNA-binding properties of the Type III-A CRISPR-associated protein Csm3Structural and functional analysis of the three MIF4G domains of nonsense-mediated decay factor UPF2Phospho-dependent and phospho-independent interactions of the helicase UPF1 with the NMD factors SMG5–SMG7 and SMG6Role for Upf2p phosphorylation in Saccharomyces cerevisiae nonsense-mediated mRNA decay.Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryDomain architectures and characterization of an RNA-binding protein, TLSRNA-binding proteins: modular design for efficient functionThe RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNAInteractions between Upf1 and the decapping factors Edc3 and Pat1 in Saccharomyces cerevisiae.The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay.Disorders with similar clinical phenotypes reveal underlying genetic interaction: SATB2 acts as an activator of the UPF3B gene.Assembly of the SLIP1-SLBP complex on histone mRNA requires heterodimerization and sequential binding of SLBP followed by SLIP1.A post-translational regulatory switch on UPF1 controls targeted mRNA degradationDrosophila Upf1 and Upf2 loss of function inhibits cell growth and causes animal death in a Upf3-independent mannerNonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question.A highly conserved region essential for NMD in the Upf2 N-terminal domainStructural basis of pre-mRNA recognition by the human cleavage factor Im complex
P2860
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P2860
The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3
description
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im April 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific article (publication date: April 2004)
@en
vedecký článok (publikovaný 2004-04)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd in 2004-04)
@nl
наукова стаття, опублікована у квітні 2004
@uk
مقالة علمية (نشرت في أبريل 2004)
@ar
name
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@ast
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@en
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@nl
type
label
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@ast
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@en
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@nl
prefLabel
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@ast
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@en
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@nl
P50
P3181
P356
P1476
The structural basis for the i ...... NA decay factors UPF2 and UPF3
@en
P2888
P3181
P356
10.1038/NSMB741
P407
P577
2004-04-01T00:00:00Z