Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen
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Regulation of glucose metabolism by p53: emerging new roles for the tumor suppressorHexokinase II detachment from the mitochondria potentiates cisplatin induced cytotoxicity through a caspase-2 dependent mechanismHexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapyWarburg Effect - a Consequence or the Cause of Carcinogenesis?Glucose metabolism in gastric cancer: The cutting-edgeMetabolic interplay between glycolysis and mitochondrial oxidation: The reverse Warburg effect and its therapeutic implicationImaging mitochondrial redox potential and its possible link to tumor metastatic potentialIs cancer a metabolic disease?The diverse role of the PPARγ coactivator 1 family of transcriptional coactivators in cancerROS homeostasis and metabolism: a critical liaison for cancer therapyMolecular Connections between Cancer Cell Metabolism and the Tumor MicroenvironmentImaging tumor metabolism using positron emission tomographyHexokinase-II positively regulates glucose starvation-induced autophagy through TORC1 inhibitionTherapeutic efficacy and safety of paclitaxel/lonidamine loaded EGFR-targeted nanoparticles for the treatment of multi-drug resistant cancerHexokinase II knockdown results in exaggerated cardiac hypertrophy via increased ROS productionMethyl jasmonate: putative mechanisms of action on cancer cells cycle, metabolism, and apoptosisAcidification asymmetrically affects voltage-dependent anion channel implicating the involvement of salt bridges.The voltage-dependent anion selective channel 1 (VDAC1) topography in the mitochondrial outer membrane as detected in intact cell.Metformin impairs glucose consumption and survival in Calu-1 cells by direct inhibition of hexokinase-II.Analysis and interpretation of transcriptomic data obtained from extended Warburg effect genes in patients with clear cell renal cell carcinoma.The Warburg effect suppresses oxidative stress induced apoptosis in a yeast model for cancer.The control systems structures of energy metabolism.Metabolic targeting of malignant tumors: small-molecule inhibitors of bioenergetic flux.Regulation of pyruvate metabolism and human diseaseApplication of the principles of systems biology and Wiener's cybernetics for analysis of regulation of energy fluxes in muscle cells in vivo.Perspective beyond cancer genomics: bioenergetics of cancer stem cellsAdding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report.Arabidopsis voltage-dependent anion channel 1 (AtVDAC1) is required for female development and maintenance of mitochondrial functions related to energy-transactionBromopyruvate mediates autophagy and cardiolipin degradation to monolyso-cardiolipin in GL15 glioblastoma cells.Cancer physics: diagnostics based on damped cellular elastoelectrical vibrations in microtubules.GLUT-1 expression is largely unrelated to both hypoxia and the Warburg phenotype in squamous cell carcinomas of the vulva.Free tubulin modulates mitochondrial membrane potential in cancer cells.Rebound thymic hyperplasia detected by 18F-FDG PET/CT after radioactive iodine ablation therapy for thyroid cancer.Role of hypoxia and glycolysis in the development of multi-drug resistance in human tumor cells and the establishment of an orthotopic multi-drug resistant tumor model in nude mice using hypoxic pre-conditioning.Voltage-dependent anion channel 1-based peptides interact with hexokinase to prevent its anti-apoptotic activity.Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy.Multi-modal strategies for overcoming tumor drug resistance: hypoxia, the Warburg effect, stem cells, and multifunctional nanotechnology.Rapid analysis of glycolytic and oxidative substrate flux of cancer cells in a microplateGlycolytic inhibitors 2-deoxyglucose and 3-bromopyruvate synergize with photodynamic therapy respectively to inhibit cell migration.Combination therapy targeting cancer metabolism.
P2860
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P2860
Warburg, me and Hexokinase 2: Multiple discoveries of key molecular events underlying one of cancers' most common phenotypes, the "Warburg Effect", i.e., elevated glycolysis in the presence of oxygen
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@ast
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@en
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@nl
type
label
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@ast
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@en
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@nl
prefLabel
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@ast
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@en
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@nl
P2860
P3181
P1476
Warburg, me and Hexokinase 2: ...... ysis in the presence of oxygen
@en
P2093
Peter L Pedersen
P2860
P2888
P304
P3181
P356
10.1007/S10863-007-9094-X
P407
P577
2007-06-01T00:00:00Z
P6179
1036348518