Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
about
The function of APC/CCdh1 in cell cycle and beyondCullin-RING ubiquitin ligases: global regulation and activation cyclesAcetylation-dependent regulation of Skp2 functionSilencing of KIF14 interferes with cell cycle progression and cytokinesis by blocking the p27(Kip1) ubiquitination pathway in hepatocellular carcinomaRegulation of p27 degradation and S-phase progression by Ro52 RING finger proteinEmi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitorUbiquitination of Keap1, a BTB-Kelch substrate adaptor protein for Cul3, targets Keap1 for degradation by a proteasome-independent pathwayThe glomuvenous malformation protein Glomulin binds Rbx1 and regulates cullin RING ligase-mediated turnover of Fbw7The ubiquitin-specific protease USP28 is required for MYC stabilityPhosphorylation of Skp2 regulated by CDK2 and Cdc14B protects it from degradation by APC(Cdh1) in G1 phaseRegulation of late G1/S phase transition and APC Cdh1 by reactive oxygen speciesThe adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memoryPhosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destructionRole of Cks1 overexpression in oral squamous cell carcinomas: cooperation with Skp2 in promoting p27 degradationPhosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complexFunctional importance of the anaphase-promoting complex-Cdh1-mediated degradation of TMAP/CKAP2 in regulation of spindle function and cytokinesis.Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells.Insights into APC/C: from cellular function to diseases and therapeuticsThe Importance of Ubiquitin E3 Ligases, SCF and APC/C, in Human CancersNetwork calisthenics: control of E2F dynamics in cell cycle entryRegulation of Unperturbed DNA Replication by UbiquitylationFunctional characterization of Anaphase Promoting Complex/Cyclosome (APC/C) E3 ubiquitin ligases in tumorigenesisThe predator becomes the prey: regulating the ubiquitin system by ubiquitylation and degradationActivation of the S-phase checkpoint inhibits degradation of the F-box protein Dia2Novel interaction between Apc5p and Rsp5p in an intracellular signaling pathway in Saccharomyces cerevisiaeFunction and regulation of cullin-RING ubiquitin ligasesMutant B-RAF signaling and cyclin D1 regulate Cks1/S-phase kinase-associated protein 2-mediated degradation of p27Kip1 in human melanoma cellsPhosphorylation of Ser72 is dispensable for Skp2 assembly into an active SCF ubiquitin ligase and its subcellular localizationThe SCF ubiquitin ligase: insights into a molecular machineTuberin binds p27 and negatively regulates its interaction with the SCF component Skp2Phospho-Ser/Thr-binding domains: navigating the cell cycle and DNA damage response5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear localization signalTargeting the oncogenic E3 ligase Skp2 in prostate and breast cancer cells with a novel energy restriction-mimetic agentRole of F-box protein betaTrcp1 in mammary gland development and tumorigenesisCDK4 T172 phosphorylation is central in a CDK7-dependent bidirectional CDK4/CDK2 interplay mediated by p21 phosphorylation at the restriction pointRegulation of postsynaptic RapGAP SPAR by Polo-like kinase 2 and the SCFbeta-TRCP ubiquitin ligase in hippocampal neuronsCdk5 phosphorylates Cdh1 and modulates cyclin B1 stability in excitotoxicityThe APC/C inhibitor, Emi1, is essential for prevention of rereplicationPrometaphase APCcdh1 activity prevents non-disjunction in mammalian oocytes.Regulation of mitochondrial morphology by APC/CCdh1-mediated control of Drp1 stability
P2860
Q21203555-9CC0B261-F523-4439-BFE4-20F8CCC7C8DFQ21203558-1D15308F-6DBD-4454-A2D5-60591B068374Q24292805-320E0B20-603A-4B95-8200-EDFE1BB44252Q24298070-02A53760-1DA7-4ACD-8865-588A00061586Q24298491-64CD19AA-B5F5-4418-B6A5-8E764943D621Q24300354-E9907525-E53F-48C6-A469-86C1E41212E0Q24306215-515E28AD-AB2A-441A-801E-770384FE3A95Q24307181-22E44D39-249B-4F3A-B224-A3C7F959B1D3Q24308568-E90A97B2-E468-4AC1-9515-E6D4DFB20542Q24309424-A0C07E44-C1C6-49FB-B7C8-21F2E49B93A7Q24548975-CA21A2B6-F4AD-418B-8CA0-8676C77DC52EQ24598286-685AD47D-39B6-4C35-AA63-D918CD95FB10Q24602385-0C4BB7F8-7E3D-473B-AD9D-46D278AB91B2Q24669893-931F9221-944C-4B8B-BB7B-6CB2E5C35698Q24670129-4BFEA821-6068-4983-9086-9798E49F6710Q24683190-177846D7-F36F-4FCF-B6FC-644279CDB6CBQ25257349-0924BE2F-8F90-46CC-B3BE-1181C333421AQ26740196-2AC539FB-5165-4D38-A77A-F7BBEBA06F34Q26777305-841801D6-B69E-4D58-9954-E39AC164107BQ26824409-8D9757B7-4789-46DD-A0FE-231E9F057140Q26853389-CA6CB2D7-EFB3-4BAD-B097-E16FD81864CDQ26998944-F3A140F2-C780-4B64-909E-1C6B2C63636DQ27687790-E1365D4B-959E-4929-99BB-1EE8F7D36B5CQ27931085-E8367D00-AC11-4B06-AA62-5590EE571637Q27931731-74051B99-0D08-4A12-8EDF-A9579077F13BQ28131707-B75EAC2F-1A36-4DEE-B107-42753309A5B5Q28259285-55414205-86A9-46F7-9A31-8FE7B658C9DBQ28273339-DAC88E16-30B7-4DFD-B5CA-DE66772D05D5Q28279993-BDABD819-99A8-41BC-9C46-13A6A3ABC1DDQ28281015-317DF978-5A99-4F0C-8C88-B469645E2ACEQ28297156-9B13B184-EDEA-445B-AA10-15356BE82442Q28384242-945C17F6-44F9-411E-BC4C-704BAC0D76EDQ28484382-48783369-CBC5-44D9-BCEB-7CA1BF10D654Q28508088-514F95ED-E653-46B6-8BCD-B4DAD2965BE0Q28533417-638FF348-394E-4FDA-B3B6-5470A1C42F2BQ28577634-6E473AAF-F09D-4EE6-857E-6DBD6B308BB2Q28580995-870021F3-7FFD-4C2F-B8D8-523FC05A8CD2Q30442630-AF7DC1A6-F2BF-4157-BBD6-9F0C96D9CAABQ30481728-8AF62A29-FA8B-457B-8622-0896518830D0Q30499681-FCC95485-FB37-4DC1-AB80-BFE72F1CD527
P2860
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
description
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Nature
@fr
artículu científicu espublizáu en 2004
@ast
scientific article (publication date: 11 March 2004)
@en
vedecký článok (publikovaný 2004/03/11)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/03/11)
@nl
наукова стаття, опублікована в березні 2004
@uk
مقالة علمية (نشرت في 11-3-2004)
@ar
name
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@ast
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@en
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@nl
type
label
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@ast
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@en
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@nl
prefLabel
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@ast
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@en
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@nl
P2093
P3181
P356
P1433
P1476
Control of the SCF(Skp2-Cks1) ubiquitin ligase by the APC/C(Cdh1) ubiquitin ligase
@en
P2093
N Valerio Dorrello
Tarig Bashir
Virginia Amador
P2888
P3181
P356
10.1038/NATURE02330
P407
P577
2004-03-11T00:00:00Z
P5875
P6179
1016208017