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Purine biosynthesis in archaea: variations on a themeThe Impact of Non-Enzymatic Reactions and Enzyme Promiscuity on Cellular Metabolism during (Oxidative) Stress Conditionsk-OptForce: integrating kinetics with flux balance analysis for strain designRapid bursts and slow declines: on the possible evolutionary trajectories of enzymesMechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes.Addition of Escherichia coli K-12 growth observation and gene essentiality data to the EcoCyc databaseA study in molecular contingency: glutamine phosphoribosylpyrophosphate amidotransferase is a promiscuous and evolvable phosphoribosylanthranilate isomerase.De novo designed proteins from a library of artificial sequences function in Escherichia coli and enable cell growthA genome-scale metabolic flux model of Escherichia coli K-12 derived from the EcoCyc database.Artificial gene amplification reveals an abundance of promiscuous resistance determinants in Escherichia coliNetwork-level architecture and the evolutionary potential of underground metabolism.Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5'-phosphate synthesis.Out of fuzzy chemistry: from prebiotic chemistry to metabolic networks.EcoCyc: fusing model organism databases with systems biology.Escherichia coli D-malate dehydrogenase, a generalist enzyme active in the leucine biosynthesis pathwayEvolving promiscuously.The EcoCyc Database.Does habitat variability really promote metabolic network modularity?An alternate pathway of arsenate resistance in E. coli mediated by the glutathione S-transferase GstB.Divergent evolution of a bifunctional de novo proteinThe proportion of genes in a functional category is linked to mass-specific metabolic rate and lifespanFutile cycling increases sensitivity toward oxidative stress in Escherichia coli.Toward a systems biology perspective on enzyme evolution.Evolution of new functions de novo and from preexisting genes.Rapid Increase in frequency of gene copy-number variants during experimental evolution in Caenorhabditis elegansEssential Genome of the Metabolically Versatile Alphaproteobacterium Rhodopseudomonas palustrisSystems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5'-Phosphate Production in E. coliA protein constructed de novo enables cell growth by altering gene regulation.Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDISDynamic metabolic engineering: New strategies for developing responsive cell factories.Quantitative assessment of thermodynamic constraints on the solution space of genome-scale metabolic models.Substrate ambiguous enzymes within the Escherichia coli proteome offer different evolutionary solutions to the same problem.Copy-number changes in evolution: rates, fitness effects and adaptive significance.A genome wide dosage suppressor network reveals genomic robustness.Limited influence of oxygen on the evolution of chemical diversity in metabolic networks.Enzyme recruitment and its role in metabolic expansion.Elucidating dynamic metabolic physiology through network integration of quantitative time-course metabolomics.Copy number change: evolving views on gene amplification.Current understanding of the formation and adaptation of metabolic systems based on network theory.A comparative study of the evolution of cellobiose utilization in Escherichia coli and Shigella sonnei.
P2860
Q21203751-BEA4516E-39CA-4B37-8853-607CA9DCCC36Q26785889-36185C0F-C271-4A34-A173-480355CE63F6Q28539934-26AABED3-DB43-4BA3-B068-4834E0089D16Q28607014-BF895A28-D0C6-4ACE-B3A3-F8A74F38157FQ30391193-90E4C968-676A-4AA0-AC1F-F8BDFD202F4EQ30723217-B775C08C-47B5-49D4-9392-4CE798F64577Q33319652-21D43F67-17A1-494C-A0DC-1FA1FDBB904FQ33796545-610EF7CF-C525-4F0D-8C85-CE6C33ADCCE3Q33863113-789BF457-B226-4F0A-8386-D42B287CAA5AQ34025067-6557F7FC-B1B8-48A8-AEF6-6622C09015ECQ34060771-E278892D-A78D-4E1A-BF55-D18D626DE458Q34152573-CB4791FE-583A-4368-8C20-E3923EF293DBQ34268582-DA1B94AD-1F22-4D3C-B8B9-28AEB983C87CQ34311072-279514C8-BB6B-4EDE-91A7-0F25F5FB3B2DQ34355701-C37207B8-8909-434C-90EC-C9C33469770EQ34533881-A46AD8EA-83DB-4F04-A02B-24F2EB396A6AQ34568046-98164102-8CD5-4EF6-A19E-E69715BC76E8Q34674915-26822F83-77BC-4EE1-A747-4937325D76F3Q35213052-D61A5C2C-BE1C-4A66-B079-217966FBB487Q35446712-CF49B391-D2B0-40C9-A832-9EDE0368D03EQ35574926-FDB2F095-1B1D-4437-B5D7-2DBDD942C1ECQ35602663-3C476679-BB09-4898-B6B0-B69F0A1BA90AQ35643651-A7191E49-05BB-42FF-BD61-EE26D5DBA363Q35663923-98F1FA2D-200A-4583-B273-925C123E5814Q35863160-79129E46-E0D4-494A-8ADB-24757AFF7318Q35880296-E31C293E-8423-4808-BE1F-BBA13CD5B68DQ35907320-0DECA297-7F4D-486D-B480-3CE36A263C44Q35925579-B6BFAD60-84FC-41BE-B8A9-BF1777010CAFQ36123634-4E8F923C-E551-4AAB-AB4E-B255CADFF4ADQ36238821-2F862005-EC80-4EF9-8C97-608A3FCB8F42Q37023365-29F7C697-978F-4CC7-BC02-D1016A0334A8Q37346935-6BEDC7EE-8B6B-4173-A6CF-DEF815851CA2Q37379672-3DCB59C3-7E20-4005-AC60-E56925AAB95EQ37577390-CC9FB254-B62C-4B79-A992-75B518D73CA7Q37608807-D4BF1345-1102-43C2-8C21-8E04222FBFA2Q37701356-7E9E1662-E0F0-4D0C-B342-2797E4784454Q37741329-18776181-ADED-44E5-959F-2AEBD8A417EBQ38120560-A305096B-0445-4597-B9F5-669258848B4DQ38222613-A522F5D6-967D-4134-B8BB-AA259F888E1AQ38290755-4CAA4F7B-86A3-41AE-92E7-8D6481A3D8E7
P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Multicopy suppression underpins metabolic evolvability
@ast
Multicopy suppression underpins metabolic evolvability
@en
Multicopy suppression underpins metabolic evolvability
@nl
type
label
Multicopy suppression underpins metabolic evolvability
@ast
Multicopy suppression underpins metabolic evolvability
@en
Multicopy suppression underpins metabolic evolvability
@nl
prefLabel
Multicopy suppression underpins metabolic evolvability
@ast
Multicopy suppression underpins metabolic evolvability
@en
Multicopy suppression underpins metabolic evolvability
@nl
P2093
P2860
P3181
P356
P1476
Multicopy suppression underpins metabolic evolvability
@en
P2093
Dan B Swartzlander
Erik M Quandt
Ichiro Matsumura
P2860
P304
P3181
P356
10.1093/MOLBEV/MSM204
P407
P577
2007-12-01T00:00:00Z