Islet cell antigen 512 is a diabetes-specific islet autoantigen related to protein tyrosine phosphatases
about
betaIV spectrin, a new spectrin localized at axon initial segments and nodes of ranvier in the central and peripheral nervous systemMolecular cloning and characterization of PTP pi, a novel receptor-like protein-tyrosine phosphataseDephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretionICA 512, an autoantigen of type I diabetes, is an intrinsic membrane protein of neurosecretory granulesIdentification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragmentNuclear translocation of an ICA512 cytosolic fragment couples granule exocytosis and insulin expression in {beta}-cellsMolecular mimicry in autoimmune diseaseSynthesis and secretion of renin in mice with induced genetic mutationsThe immunofluorescence techniques in the diagnosis of endocrine autoimmune diseasesT-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agentsImogen 38: a novel 38-kD islet mitochondrial autoantigen recognized by T cells from a newly diagnosed type 1 diabetic patientThe diabetes autoantigen ICA69 and its Caenorhabditis elegans homologue, ric-19, are conserved regulators of neuroendocrine secretionRegulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.Distinct clinical and laboratory characteristics of latent autoimmune diabetes in adults in relation to type 1 and type 2 diabetes mellitus.Myelin Oligodendrocyte Glycoprotein: Deciphering a Target in Inflammatory Demyelinating Diseases.Immunomodulation by blockade of the TRANCE co-stimulatory pathway in murine allogeneic islet transplantation.Prediction and pathogenesis in type 1 diabetes.HLA genes, islet autoantibodies and residual C-peptide at the clinical onset of type 1 diabetes mellitus and the risk of retinopathy 15 years later.Humoral autoimmunity against the extracellular domain of the neuroendocrine autoantigen IA-2 heightens the risk of type 1 diabetesThe 37/40-kilodalton autoantigen in insulin-dependent diabetes mellitus is the putative tyrosine phosphatase IA-2.Measurement of islet cell antibodies in the Type 1 Diabetes Genetics Consortium: efforts to harmonize procedures among the laboratoriesStrategies for preventing type I diabetes mellitusLack of agreement among two commercial enzyme-linked immunosorbent antibody assays and a conventional immunofluorescence-based method for detecting islet cell autoantibodies.B cells in autoimmune diabetesAutoimmune polyglandular syndrome Type 2: the tip of an iceberg?Increased prevalence of autoimmune thyroid disease in patients with type 1 diabetesAntibody to CMRF35-Like Molecule 2, CD300e A Novel Biomarker Detected in Patients with Fulminant Type 1 Diabetes.Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application.The core cysteines, (C909) of islet antigen-2 and (C945) of islet antigen-2β, are crucial to autoantibody binding in type 1 diabetes.T-cell epitope analysis using subtracted expression libraries (TEASEL): application to a 38-kDA autoantigen recognized by T cells from an insulin-dependent diabetic patient.An islet-cell protein tyrosine phosphatase is a likely precursor to the 37-kDa autoantigen in type 1 diabetes: human and macaque sequences, tissue distribution, unique and shared epitopes, and predictive autoantibodies.Dense-core vesicle proteins IA-2 and IA-2{beta} affect renin synthesis and secretion through the {beta}-adrenergic pathway.Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice.Pituitary Microsomal Autoantibodies in Patients with Childhood-Onset Combined Pituitary Hormone Deficiency: an Antigen Identification AttemptIA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.Current approaches to measuring human islet-antigen specific T cell function in type 1 diabetes.T cell recognition of autoantigens in human type 1 diabetes: clinical perspectivesRelationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).Late-onset islet autoimmunity in childhood: the Diabetes Autoimmunity Study in the Young (DAISY).Detection of Islet Cell Immune Reactivity with Low Glycemic Index Foods: Is This a Concern for Type 1 Diabetes?
P2860
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P2860
Islet cell antigen 512 is a diabetes-specific islet autoantigen related to protein tyrosine phosphatases
description
1994 nî lūn-bûn
@nan
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@ast
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@en
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@nl
type
label
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@ast
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@en
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@nl
prefLabel
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@ast
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@en
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@nl
P2093
P3181
P1476
Islet cell antigen 512 is a di ...... protein tyrosine phosphatases
@en
P2093
D E Goldstein
H Yoo-Warren
J A Shapiro
S M Pleasic
P304
P3181
P407
P577
1994-03-15T00:00:00Z