Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).
about
Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetesIdentification of a second transmembrane protein tyrosine phosphatase, IA-2beta, as an autoantigen in insulin-dependent diabetes mellitus: precursor of the 37-kDa tryptic fragmentRecombinant Lactococcus lactis can make the difference in antigen-specific immune tolerance induction, the Type 1 Diabetes caseIDA-1, a Caenorhabditis elegans homolog of the diabetic autoantigens IA-2 and phogrin, is expressed in peptidergic neurons in the worm.Distinct clinical and laboratory characteristics of latent autoimmune diabetes in adults in relation to type 1 and type 2 diabetes mellitus.Autoantigen-specific regulatory T cells induced in patients with type 1 diabetes mellitus by insulin B-chain immunotherapy.HLA genes, islet autoantibodies and residual C-peptide at the clinical onset of type 1 diabetes mellitus and the risk of retinopathy 15 years later.The dense core transmembrane vesicle protein IA-2 is a regulator of vesicle number and insulin secretion.Presence of diabetes autoantigens in extracellular vesicles derived from human islets.Measurement of islet cell antibodies in the Type 1 Diabetes Genetics Consortium: efforts to harmonize procedures among the laboratoriesA comparison of the baseline metabolic profiles between Diabetes Prevention Trial-Type 1 and TrialNet Natural History Study participants.The Sardinian way to type 1 diabetes.Autoimmune gestational diabetes mellitus: a distinct clinical entity?Molecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells.GAD65-reactive T cells are activated in patients with autoimmune type 1a diabetes.B cells in autoimmune diabetesAntigen targets of type 1 diabetes autoimmunityNovel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application.Zinc transporter 8 autoantibodies and their association with SLC30A8 and HLA-DQ genes differ between immigrant and Swedish patients with newly diagnosed type 1 diabetes in the Better Diabetes Diagnosis studyHumoral and cellular immune parameters before and during immunosuppressive therapy of a patient with stiff-man syndrome and insulin dependent diabetes mellitus.The core cysteines, (C909) of islet antigen-2 and (C945) of islet antigen-2β, are crucial to autoantibody binding in type 1 diabetes.Translational mini-review series on type 1 diabetes: Systematic analysis of T cell epitopes in autoimmune diabetes.Expression-Based Genome-Wide Association Study Links Vitamin D-Binding Protein With Autoantigenicity in Type 1 Diabetes.An islet-cell protein tyrosine phosphatase is a likely precursor to the 37-kDa autoantigen in type 1 diabetes: human and macaque sequences, tissue distribution, unique and shared epitopes, and predictive autoantibodies.B Cell in Autoimmune Diseases.Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice.Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD65 and IA2 marks the early phases of autoimmune response in type 1 diabetes.Natural evolution, prediction, and prevention of type 1 diabetes in youth.Prediction of insulin-dependent diabetes mellitus in siblings of children with diabetes. A population-based study. The Childhood Diabetes in Finland Study Group.Pancreatic islet autoantibodies as predictors of type 1 diabetes in the Diabetes Prevention Trial-Type 1.IA-2, a transmembrane protein of the protein tyrosine phosphatase family, is a major autoantigen in insulin-dependent diabetes mellitus.Autoimmunity and the pathogenesis of type 1 diabetes.Group B coxsackieviruses and autoimmunity: focus on Type 1 diabetes.Prevention and treatment of type 1 diabetes mellitus by the manipulation of invariant natural killer T cells.Heterophile antibodies indicate progression of autoimmunity in human type 1 diabetes mellitus before clinical onset.Associations of human leukocyte antigens with autoimmune diseases: challenges in identifying the mechanism.Islet Autoantibody Analysis: Radioimmunoassays.Prediction of type 1 diabetes in Sardinian schoolchildren using islet cell autoantibodies: 10-year follow-up of the Sardinian schoolchildren type 1 diabetes prediction study.Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4.Islet cell antigens in the prediction and prevention of insulin-dependent diabetes mellitus.
P2860
Q24322739-33E40613-4414-455F-B615-A0B84C1DD8E7Q24567712-810C6E09-298E-4B68-BB7A-2C6EB9D2F057Q27028100-7DDDB9AA-4425-4D88-A825-9556392B8D2FQ31585217-9D30D67C-36B5-458D-8819-1AF1D631CF2AQ33358948-659F6B50-1140-4E97-9AFD-74DC7FD822B9Q33811894-55FB5CE2-EA27-4BD3-866A-331E297D11FFQ33848973-EF0AC563-F2CB-4F2F-8AEB-3A48558647E7Q33853806-F0A2AA4F-0D75-4B5B-BBB0-933E61B63900Q33890308-463C45D7-B8EA-409C-A860-F82F9A8F3DF7Q34051605-9A42923F-487C-4991-AB3A-D712EED70D73Q34200419-EA669089-21AD-4D76-8249-3F906D4DB252Q34209163-72F621DC-61D9-492D-9BAE-B2D0AC7918DDQ34470630-4ACEF886-788C-41B7-9A07-96BBD91F9F36Q34737266-6A0E4242-48CA-42FC-AA25-89A95612A555Q34790295-E72BF992-B357-47BA-9230-449FA53BE8CAQ35612697-B5B5A8D5-7BD8-4BDD-BCD5-E898CB0B65D2Q35852999-9D6216E6-57B6-40B0-B11B-37D535F4274EQ36202941-F1D83684-1362-4EC8-99F0-F6B8E2A38906Q36249785-EBE8888F-00AE-4834-96C6-859F5D3883BFQ36318504-6ED5F0D4-FAD9-4000-B7F8-E1D5ED059F8FQ36477325-1ADF9D9B-E53D-453F-8612-A1BF93942F4DQ36755911-080240D1-E62C-4190-90B2-766C7CCD1021Q36820754-61DDB319-7C71-4650-BD0D-A30339657B95Q36853549-8FE80A60-04ED-485D-84B1-F4F7CEF7BFD2Q36954468-EC35D3AB-BC1D-4B9F-A45B-3F7B61454FBBQ37248995-590C6F4E-BD3B-492E-8F18-DC0A1731E667Q37356382-C799FD98-7BD8-4246-AF0B-FD7BAA1293C1Q37373473-566F9130-69BD-4D65-A5E8-8E2E24743EBAQ37377371-F0DC3A95-2577-4F14-BB91-53039F92F0F2Q37437161-77D52787-D8D0-4E0A-A88C-D0C1A2A31421Q37518209-0CDF8C0C-F640-4664-990D-4A66A47D4F22Q37764866-5F18035F-72E9-49FF-81C0-C1025A887D51Q37877267-FDCD78FC-5F74-4A03-94F7-417313833BEAQ38028844-A4AA254D-70D6-414F-8902-89708CA3959BQ38457334-19B26F3E-F5EE-432F-8F78-B896492E0285Q38569872-2DC95D7E-4970-4B51-8BD4-B703D5703145Q38932737-37FFE6BE-D2CD-439D-BBE4-5C6BCB7F2D54Q39015884-B71D854B-6731-4E8F-BA2C-4EF6A5935C6BQ40857730-B1DDAF06-4E70-4AE0-9CDB-91AD735153B0Q40870952-4E1E655B-41C6-4A0A-A849-CD9A8050A2E3
P2860
Relationship of the 37,000- and 40,000-M(r) tryptic fragments of islet antigens in insulin-dependent diabetes to the protein tyrosine phosphatase-like molecule IA-2 (ICA512).
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年学术文章
@wuu
1995年学术文章
@zh-cn
1995年学术文章
@zh-hans
1995年学术文章
@zh-my
1995年学术文章
@zh-sg
1995年學術文章
@yue
1995年學術文章
@zh
1995年學術文章
@zh-hant
name
Relationship of the 37,000- an ...... e-like molecule IA-2 (ICA512).
@en
type
label
Relationship of the 37,000- an ...... e-like molecule IA-2 (ICA512).
@en
prefLabel
Relationship of the 37,000- an ...... e-like molecule IA-2 (ICA512).
@en
P2093
P2860
P356
P1476
Relationship of the 37,000- an ...... e-like molecule IA-2 (ICA512).
@en
P2093
P2860
P304
P356
10.1172/JCI118188
P407
P577
1995-09-01T00:00:00Z