Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant IRS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1
about
Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor.Identification of a LNCaP-specific binding peptide using phage display.Tumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA.DNA and RNA derivatives to optimize distribution and deliveryPromiscuous 8-alkoxyadenosines in the guide strand of an siRNA: modulation of silencing efficacy and off-pathway protein binding.Genetic variation in candidate obesity genes ADRB2, ADRB3, GHRL, HSD11B1, IRS1, IRS2, and SHC1 and risk for breast cancer in the Cancer Prevention Study II.Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides.The delivery of therapeutic oligonucleotidesThe role of carrier size in the pharmacodynamics of antisense and siRNA oligonucleotides.Cellular delivery of siRNA and antisense oligonucleotides via receptor-mediated endocytosis.Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides.Oligonucleotide conjugates for therapeutic applications.Advances in targeted delivery of small interfering RNA using simple bioconjugates.New Modalities for Challenging Targets in Drug Discovery.Bioconjugates for targeted delivery of therapeutic oligonucleotides.Peptide nucleic acid (PNA) cell penetrating peptide (CPP) conjugates as carriers for cellular delivery of antisense oligomers.Functional peptides for siRNA delivery.Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.Targeted intracellular delivery of antisense oligonucleotides via conjugation with small-molecule ligands.Cellular delivery and biological activity of antisense oligonucleotides conjugated to a targeted protein carrier.Molecular Mechanisms and Biological Functions of siRNA.Optimized siRNA-PEG conjugates for extended blood circulation and reduced urine excretion in miceCryptotanshinone inhibition of mammalian target of rapamycin pathway is dependent on oestrogen receptor alpha in breast cancer.
P2860
Q30434397-EEE4CA0C-7199-46A1-B4DD-AF960FDA5D6BQ33911470-28F6188D-7193-414D-B285-66CA232F3521Q34313026-D1A28D20-F8DE-4FAA-9A70-646865A41CC9Q35858691-46415F18-7DF1-404D-BBF7-1C2F0394D924Q36379706-D91CAD64-F1FE-48EF-BF96-647A1C4511E5Q36955072-215BCEA3-3723-4971-9582-F3CDEEEB2771Q37193000-BBA21EAD-26AF-4662-9EC7-0EADF689D2CAQ37210936-CEF2EE4D-51A9-4594-A33E-8B1BAC415554Q37724167-4AE16017-C296-4C7C-A678-EE10E5760CF3Q37850458-7CE3CF85-6638-421B-BA0E-B00E20DA730DQ37944929-367BFC16-AF89-4FCB-A908-88A5937C885CQ38123854-263A1CDC-2BB9-4440-8FAF-5E289689CF21Q38199518-079ADC97-39AE-4BFF-8F36-2D783A453B03Q38289100-D2EB07D0-89EE-427C-8315-D4E34E6FAE10Q38301011-A8B1FC9C-F391-4F6C-A0EA-2FD5961A3547Q38325571-3004DE06-58EE-4312-8B3E-C4056C461DD3Q38928987-346360A1-D846-4FEA-9B68-E43C41292C7CQ39506968-98044A7C-7F99-46A5-A423-3FD2DA6D51DCQ39692815-32BB0B61-15D3-4554-A523-632477D97E02Q39934164-18EE038C-9627-49EB-B2D7-15A4C44EF9BBQ40077184-49D3AA10-DA8C-497C-81F1-386365EBCC07Q41507502-0B409017-DB0A-40F2-83A0-52A51B7AAA38Q41520280-5183FD98-B5BF-4091-8C54-E7386A977D12
P2860
Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant IRS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1
description
2007 nî lūn-bûn
@nan
2007 թուականին հրատարակուած գիտական յօդուած
@hyw
2007 թվականին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@ast
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@en
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@nl
type
label
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@ast
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@en
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@nl
prefLabel
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@ast
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@en
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@nl
P2093
P3181
P356
P1476
Insulin receptor substrate 1 k ...... f insulin-like growth factor 1
@en
P2093
Chang-Po Chen
Eric Wickstrom
Gregory Cesarone
Om Prakash Edupuganti
P304
P3181
P356
10.1021/BC070135V
P407
P577
2007-01-01T00:00:00Z