Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA. - Wikidata - awgldk - TriplyDB

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

http://www.wikidata.org/entity/Q39506968

about

Technologies for controlled, local delivery of siRNA Tumor-targeted in vivo gene silencing via systemic delivery of cRGD-conjugated siRNA.High-throughput screening identifies small molecules that enhance the pharmacological effects of oligonucleotides.Nucleic Acid Bioconjugates in Cancer Detection and Therapy.The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides.Receptors, endocytosis, and trafficking: the biological basis of targeted delivery of antisense and siRNA oligonucleotides The delivery of therapeutic oligonucleotides New aspects of gene-silencing for the treatment of cardiovascular diseases Cellular uptake and intracellular trafficking of oligonucleotides: implications for oligonucleotide pharmacology.RNA interference trigger variants: getting the most out of RNA for RNA interference-based therapeutics Oligonucleotide conjugates for therapeutic applications.Advances in targeted delivery of small interfering RNA using simple bioconjugates.New Modalities for Challenging Targets in Drug Discovery.Bioconjugates for targeted delivery of therapeutic oligonucleotides.Cellular uptake and intracellular trafficking of oligonucleotides A tumor-targeting cRGD-EGFR siRNA conjugate and its anti-tumor effect on glioblastoma in vitro and in vivo.Functional peptides for siRNA delivery.Conjugation with receptor-targeted histidine-rich peptides enhances the pharmacological effectiveness of antisense oligonucleotides Targeted delivery of antisense oligonucleotides by chemically self-assembled nanostructures.Nanolayered siRNA dressing for sustained localized knockdown.Targeted delivery of a splice-switching oligonucleotide by cationic polyplexes of RGD-oligonucleotide conjugate.Hydrophobic interactions between polymeric carrier and palmitic acid-conjugated siRNA improve PEGylated polyplex stability and enhance in vivo pharmacokinetics and tumor gene silencing The chemistry and biology of oligonucleotide conjugates.Defined Folate-PEG-siRNA Conjugates for Receptor-specific Gene Silencing.Peptide-mediated Cell and In Vivo Delivery of Antisense Oligonucleotides and siRNA.Reductive nanocomplex encapsulation of cRGD-siRNA conjugates for enhanced targeting to cancer cells.Conjugation of palmitic acid improves potency and longevity of siRNA delivered via endosomolytic polymer nanoparticles.Covalent conjugation of oligonucleotides with cell-targeting ligands.Acidic pH-responsive siRNA conjugate for reversible carrier stability and accelerated endosomal escape with reduced IFNα-associated immune response.Delivery Pathway Regulation of 3′,3″-Bis-Peptide-siRNA Conjugate via Nanocarrier Architecture Engineering.Utility of the 2-Nitrobenzenesulfonamide Group as a Chemical Linker for Enhanced Extracellular Stability and Cytosolic Cleavage in siRNA-Conjugated Polymer Systems.Chemical modifications of nucleic acid drugs and their delivery systems for gene-based therapy.Comparative Characterization of Hepatic Distribution and mRNA Reduction of Antisense Oligonucleotides Conjugated with Triantennary N-Acetyl Galactosamine and Lipophilic Ligands Targeting Apolipoprotein B.Improved method for synthesis of low molecular weight protamine-siRNA conjugate.Effect of multiple cyclic RGD peptides on tumor accumulation and intratumoral distribution of IRDye 700DX-conjugated polymers.An Efficient Bivalent Cyclic RGD-PIK3CB siRNA Conjugate for Specific Targeted Therapy against Glioblastoma In Vitro and In Vivo

P2860

Q28087657-52DA9375-B521-4267-B04B-738C635D7A0B Q34313026-423DE33A-CF51-452F-9729-FB41DC1F1C4F Q35131115-2AC83FFA-0F72-48F0-B059-7F680B9502A3 Q35867875-2ECBB779-877C-4D51-863F-65EE7B3B6EC6 Q36740806-35841232-240E-4FC2-AC21-84BB6B94C2F1 Q37015817-CE12F6B8-68F0-43EA-B91C-7ECF739F01AB Q37210936-3BFC4645-4F0D-43F5-AE44-226763C2E676 Q37277425-6045968F-11A4-45B5-BBF3-1EA660924E38 Q37656119-67D5EEB2-E1F2-4FC3-9047-A5031E3E24EB Q38019046-2556C87E-D421-42A3-AEB6-7194D68C08E9 Q38123854-37D6B1BD-D620-489C-8A15-FC4E40F87A8D Q38199518-598D8523-CC52-4AB6-8EB3-E8B678F42911 Q38289100-36AFABB2-408C-4DF6-8F87-1A6F44B4241F Q38301011-E138C951-0AED-49C3-85C2-E4B20D582C09 Q38424377-44BE28DD-8752-49C9-9F48-DB2280B23C9D Q38717131-EFAD1B06-C86B-4ED7-A26E-71C69FD1E59C Q38928987-EE493820-CB6C-4B5A-9603-0C2BE239D326 Q39041906-70D61DAF-1ECC-4BE0-9C53-89EAC6C59924 Q39129886-60E308FF-92F9-4FAE-A76B-BF12C0F8D667 Q39152253-AC30000F-1DEB-4655-9646-43F2EE2FA0F6 Q39365338-1A501F04-434F-485C-9E84-D08C0F54A3FE Q39779323-F0C1BEEB-F266-46B6-B040-C5FA34A00D28 Q42011018-3795853A-3F66-4E0D-807E-8F3B793DB45D Q42155861-ABCD5C96-1367-4E5B-978C-DA5B006ED7F2 Q42226373-70FE4271-C415-4FEB-A90B-FDF67F27BECC Q42373829-4F6DDBD7-050E-4CEF-8FA3-0D57C80F918C Q42408555-0BDEB599-6BEA-4759-A1B9-A5129810DD24 Q42958209-D6118E9A-54C9-4ACC-8E1C-9713A321ACA6 Q46543595-AB43B535-17AF-448F-834E-8B792EEA6CA3 Q47160679-77EABEA3-AC3B-4F3C-B48D-25209720207E Q48214605-A1DA2A6E-3347-45B8-9D19-28673D419942 Q48282746-EBE8D2D6-EAF4-4050-91B2-67A9A7FBBD60 Q53631590-BC6DAC91-0A9F-4C33-82FB-D221D0798BBB Q54957884-584CD19E-3185-4433-B177-92BA9DBB21FA Q55130405-AE6E5A91-BAEB-437D-9551-4DCA601BA3AF Q57493904-6DF2ABBA-013A-4843-ADE9-22AC21E38E98

P2860

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

http://www.wikidata.org/entity/Q39506968

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

@en

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

@nl

type

label

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

@en

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

@nl

prefLabel

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

@en

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

@nl

P1433

Q39506968-FC5A49D8-57C8-4EA7-9C30-92F38B242624

P1476

Q39506968-6BA06DCC-376B-43B7-8D5A-FE85071138F8

P2093

Q39506968-0A28540C-215C-4492-8A72-2948AC98C66F

Q39506968-6E02343F-2D67-4826-A415-2053A7D587D8

Q39506968-90C9F611-E6EB-449C-ABF2-02E7017C83F6

Q39506968-96DDE5B7-DFDB-44FD-B52B-5791D969007B

Q39506968-9C992474-E4F4-40F5-B3D8-369781F2D51E

Q39506968-CDAB391B-31CC-4C4B-AFDF-95254BF14726

Q39506968-FA5E3682-0012-49FD-ADFF-FF1EE813DB08

P2860

Q39506968-06B1793D-EFC4-4BC6-BE3D-4C170E56A7EA

Q39506968-1F692A4F-CDAD-49E7-B892-26FC47B73444

Q39506968-20E4529A-3B09-4B5E-9227-1138906CE0D6

Q39506968-262D4846-C082-4DB6-AC4E-81A6F78841A7

Q39506968-28B22CB4-C8F2-4D5E-98A6-FE8673B8C1C6

Q39506968-29BFDC37-E746-4BB3-A177-4215C240BD91

Q39506968-37597973-156D-435B-8396-DE6628F820D8

Q39506968-3E156FF9-3AA4-466A-BBD7-972B948488D5

Q39506968-4AC40348-CFA4-4263-9F04-65720A089F5D

Q39506968-4ED38B8C-F23E-44DA-8C9D-C36B7FAD4759

P304

Q39506968-C363C1A7-D6BE-4144-8A1E-7F338C323444

P31

Q39506968-66037775-DCC6-4336-B06A-3E3674EF7E93

P356

Q39506968-0912FE54-8130-4D0C-B9E3-95048DEFCC73

P433

Q39506968-EDAB6580-4036-4C1B-9E84-7D37F862F8BB

P478

Q39506968-5D5764B5-778C-4B0F-A2AC-AE4C052309A8

P577

Q39506968-4E14D02C-F87A-4D3F-85A8-89C1557E96B1

P698

Q39506968-AD3BA45A-3EC2-47C0-84D4-F180A487AC5B

P932

Q39506968-4970F5AE-06B6-464D-ACE0-052903959FEB

P356

P1433

Bioconjugate Chemistry

P1476

Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA.

@en

P2093

Jeremy G Lackey

http://www.w3.org/2001/XMLSchema#string

Kallanthottathil G Rajeev

http://www.w3.org/2001/XMLSchema#string

Md Rowshon Alam

http://www.w3.org/2001/XMLSchema#string

Michael Fisher

http://www.w3.org/2001/XMLSchema#string

Muthiah Manoharan

http://www.w3.org/2001/XMLSchema#string

Rudy L Juliano

http://www.w3.org/2001/XMLSchema#string

Xin Ming

http://www.w3.org/2001/XMLSchema#string

P2860

Insulin receptor substrate 1 knockdown in human MCF7 ER+ breast cancer cells by nuclease-resistant IRS1 siRNA conjugated to a disulfide-bridged D-peptide analogue of insulin-like growth factor 1

Integrins in cancer: biological implications and therapeutic opportunities

Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor.

Lipid-like materials for low-dose, in vivo gene silencing

Nanogels as pharmaceutical carriers: finite networks of infinite capabilities

Role of alpha v integrins during angiogenesis.

A status report on RNAi therapeutics.

RNA targeting therapeutics: molecular mechanisms of antisense oligonucleotides as a therapeutic platform.

RNAi and small interfering RNAs in human disease therapeutic applications.

Involvement of integrin alpha V gene expression in human melanoma tumorigenicity

P304

1673-1681

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1021/BC200235Q

http://www.w3.org/2001/XMLSchema#string

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

22

http://www.w3.org/2001/XMLSchema#string

P577

2011-07-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

21755983

http://www.w3.org/2001/XMLSchema#string

P932

3718025

http://www.w3.org/2001/XMLSchema#string