GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function - Wikidata - awgldk - TriplyDB

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

http://www.wikidata.org/entity/Q28254935

about

Structure of an agonist-bound human A2A adenosine receptor High-resolution structure of the human GPR40 receptor bound to allosteric agonist TAK-875 Structure of the human κ-opioid receptor in complex with JDTic PROKR2 missense mutations associated with Kallmann syndrome impair receptor signalling activity Structural model of ligand-G protein-coupled receptor (GPCR) complex based on experimental double mutant cycle data: MT7 snake toxin bound to dimeric hM1 muscarinic receptor Structure of the human histamine H1 receptor complex with doxepin Structure of a nanobody-stabilized active state of the β(2) adrenoceptor A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis Structure and function of an irreversible agonist-β(2) adrenoceptor complex Crucial role of copper in detection of metal-coordinating odorants International Union of Basic and Clinical Pharmacology. LXXV. Nomenclature, classification, and pharmacology of G protein-coupled melatonin receptors.Lessons from the lysozyme of phage T4 The impact of GPCR structures on pharmacology and structure-based drug design Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist Crystal structure of the β2 adrenergic receptor-Gs protein complex Identification of two distinct inactive conformations of the beta2-adrenergic receptor reconciles structural and biochemical observations Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor Revealing Atomic-Level Mechanisms of Protein Allostery with Molecular Dynamics Simulations Engineering therapeutic antibodies targeting G-protein-coupled receptors Structural Studies of G Protein-Coupled Receptors A brief history of macromolecular crystallography, illustrated by a family tree and its Nobel fruits Structure determination of membrane proteins by nuclear magnetic resonance spectroscopy Post-expression strategies for structural investigations of membrane proteins.Diversity and modularity of G protein-coupled receptor structures Large-scale production and protein engineering of G protein-coupled receptors for structural studies Opportunities and challenges for time-resolved studies of protein structural dynamics at X-ray free-electron lasers.Metaphors, naming and new signaling paradigms by G-protein-coupled receptors To fuse or not to fuse: what is your purpose?New insights for drug design from the X-ray crystallographic structures of G-protein-coupled receptors Computational modeling of membrane proteins Fluorescent approaches for understanding interactions of ligands with G protein coupled receptors Endogenous lipid activated G protein-coupled receptors: emerging structural features from crystallography and molecular dynamics simulations Filming biomolecular processes by high-speed atomic force microscopy In meso in situ serial X-ray crystallography of soluble and membrane proteins at cryogenic temperatures.GPCR-ModSim: A comprehensive web based solution for modeling G-protein coupled receptors Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor Crystal Structure of Squid Rhodopsin with Intracellularly Extended Cytoplasmic Region Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins

P2860

Q24296388-FC2E3286-92AD-412B-AFDA-55A93FBE2DEB Q24301044-AD4D1197-4394-4A18-AE4D-4097AFF0A349 Q24308048-93B11F91-0503-4765-A19F-7EEBC6E87CF5 Q24317396-15440CAA-FC63-434F-8523-B30AB3017F9F Q24595276-9D0AF5B3-1555-4E72-B986-B20057024CFC Q24595968-E641117F-44F4-4685-B20F-D3D730F09C6E Q24597139-A2F8A48D-7161-4873-A3A8-42F760BB5934 Q24602445-3044AA6D-AD1E-40E3-831A-129F2A717F94 Q24620291-BBA6D76D-3440-4EFA-BFF9-4F48056A8AD2 Q24622965-2636914E-D468-4626-AFC6-BF70762F8F5B Q24623433-BE95EA06-0B56-47E7-9F90-E1C8657B6C45 Q24623930-0552A836-CDF8-4C64-AD75-34569137EF60 Q24628661-A11D9ACF-6914-4955-ABF7-D9CC85102D64 Q24628686-9154DB2F-CDB0-4695-B416-9D3AE1635E81 Q24635327-D8096E23-688F-4FBD-BDB8-5AA9FCA05B5B Q24645752-144189D8-E8B4-4B6F-A8E2-5F2301E622C6 Q24646942-C76F4588-6967-4EA5-A449-25EE23D78AB0 Q24654563-B7FD4B01-7696-47BF-86EF-B19698CAD6C7 Q24657484-35531143-8877-4CBC-A25E-31F13C1E33EA Q26747130-20B4170B-5C92-4FFA-854F-95AC5D609C93 Q26769017-3B5B1C9E-C764-4659-A317-685A59C8D906 Q26783016-C92C8D16-7720-48E4-8123-E032E9FD5DD1 Q26823889-8F5752E8-9D75-4295-AE8C-3F42B9987C78 Q26824924-A8568588-60AB-4264-A5BC-D4E7B6A03A94 Q26849743-B399F87E-E1E7-4260-A91F-0D6E221095ED Q26852976-E8DB0215-BDEC-4791-9F31-7D8A2888F9CF Q26866010-35E7DF09-74D8-4681-8E24-D88418D575B8 Q26866088-4E6BD63D-8EF5-4140-92D7-9A441CED150C Q26991511-46FCFBBA-8B11-42B5-A01F-7F7A521BB034 Q26991608-A457C626-2F63-4834-BC22-F4BFF9DD1951 Q26991761-7018DCE9-3A29-4FC8-ACEC-6CD5CC3AECE7 Q26995693-30CF721F-7C2E-479E-AC01-372039356C4F Q27004213-6A7AD3D7-059C-4AC5-A392-7E038304C0E2 Q27009220-25222C1F-14EC-48F8-99FF-D787A4AD6695 Q27021717-408D8CFA-2759-4094-9F41-38573076497F Q27316812-84EEA390-7F30-41BC-B6B9-6567620A3D7F Q27323329-9BA17B93-DC5E-4CBB-B98D-36C405AD3AAC Q27646733-DB12437D-284D-4BED-9C29-9F207B08AAB8 Q27650564-5309C6CC-F089-4122-8DC9-ADE513F46AFE Q27650678-690EA046-7477-4917-B533-BD3A618B5A90

P2860

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

http://www.wikidata.org/entity/Q28254935

description

2007 nî lūn-bûn

@nan

2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@ast

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@en

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@nl

type

label

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@ast

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@en

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@nl

prefLabel

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@ast

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@en

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@nl

P1433

Q28254935-F20CA612-DC12-40E0-AE3A-0252B07B77C3

P1476

Q28254935-3759C273-19F6-4727-BDF2-7FDCDFBFEFC6

P2093

Q28254935-53540096-EACC-4FC7-84D2-510AF1A2B631

Q28254935-583AA349-36E8-454C-BBC9-2F9D72C5914B

Q28254935-6B70D4EF-AC80-455E-B8C2-FC48A470CCD8

Q28254935-8E66E89D-055C-420D-86FD-9B466DBD9A06

Q28254935-E54A6A33-091C-453C-B438-EF5B7CB84A19

Q28254935-E67370C3-D01E-4E5A-A7E1-CA24908AEC13

Q28254935-EAD46691-112C-4161-A900-4973B3B62150

P2860

Q28254935-06E199FF-38FF-45FC-A760-7E71B35C482A

Q28254935-27FE3DB1-1AF5-42CF-BB2E-1C8C31A545F2

Q28254935-CFECCA29-BF62-409A-942F-BAE885D6BD77

Q28254935-EF410EBD-225B-41E4-AA38-EEFED72C3AD0

Q28254935-F659702F-9F9A-421A-943F-12FEC1E34B7C

Q28254935-F6F0FD62-75E3-4D0B-83B9-BF151F271D96

P304

Q28254935-A197635F-D5BF-4B89-BDDA-973D383BFB2E

P31

Q28254935-31722133-84AD-4AFB-B9CC-7D7E53930AC5

P3181

Q28254935-4862D82E-1C61-42EB-9894-E7985597E998

P356

Q28254935-1EA86399-AD2A-4E32-96F2-137DC8CBBE12

P407

Q28254935-068C6A8F-144E-4BEB-A7BF-2F2B98BCE0C3

P433

Q28254935-C192D013-08DB-40E5-83CB-1F412B90B608

P478

Q28254935-F0BDADF4-A378-4EF2-ACED-F3770FA86790

P50

Q28254935-14BE374A-D673-4BFC-B905-C18947812BB1

Q28254935-180A28F5-BF36-4F84-AF5A-3CEEDED71F91

Q28254935-A3203834-1EC7-4830-9785-9585BD7043A7

Q28254935-D9BDA15B-25C1-470F-AF42-DBD98B9B25E0

P577

Q28254935-3EA30D44-CE2B-4D2E-B768-34C42F36A812

P5875

Q28254935-131A50EE-94BC-4FBB-8BA0-8CB4F1439B60

P698

Q28254935-D00AD78E-A3E2-41BE-AD47-8519C6DE48ED

P921

Q28254935-A3C797B9-9D95-413A-8120-FE1B5E4064D9

P3181

P356

SCIENCE.1150609

P1433

P1476

GPCR engineering yields high-r ...... 2-adrenergic receptor function

@en

P2093

Daniel M Rosenbaum

http://www.w3.org/2001/XMLSchema#string

Foon Sun Thian

http://www.w3.org/2001/XMLSchema#string

Hee-Jung Choi

http://www.w3.org/2001/XMLSchema#string

Michael A Hanson

http://www.w3.org/2001/XMLSchema#string

Søren G F Rasmussen

http://www.w3.org/2001/XMLSchema#string

Vadim Cherezov

http://www.w3.org/2001/XMLSchema#string

Xiao-Jie Yao

http://www.w3.org/2001/XMLSchema#string

P2860

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

GPCRDB information system for G protein-coupled receptors

Crystal structure of the human beta2 adrenergic G-protein-coupled receptor

Structure of bacteriophage T4 lysozyme refined at 1.7 A resolution

Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme

Structural basis of beta-adrenergic receptor subtype specificity studied with chimeric beta 1/beta 2-adrenergic receptors

P304

1266-73

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

630752

http://www.w3.org/2001/XMLSchema#string

P356

10.1126/SCIENCE.1150609

http://www.w3.org/2001/XMLSchema#string

P407

P433

5854

http://www.w3.org/2001/XMLSchema#string

P478

318

http://www.w3.org/2001/XMLSchema#string

P50

Raymond C Stevens

Tong Sun Kobilka

P577

2007-11-23T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5882507

http://www.w3.org/2001/XMLSchema#string

P698

17962519

http://www.w3.org/2001/XMLSchema#string

P921

G protein-coupled receptor