Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway
about
Identification of two novel activities of the Wnt signaling regulator Dickkopf 3 and characterization of its expression in the mouse retinaWnt signalling in human breast cancer: expression of the putative Wnt inhibitor Dickkopf-3 (DKK3) is frequently suppressed by promoter hypermethylation in mammary tumoursModulation of LRP6-mediated Wnt signaling by molecular chaperone MesdEfficacy of Wnt-1 monoclonal antibody in sarcoma cellsTherapeutic potential of targeting acinar cell reprogramming in pancreatic cancerDickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastomaSTAT3 upregulates miR-92a to inhibit RECK expression and to promote invasiveness of lung cancer cellsAutonomous regulation of osteosarcoma cell invasiveness by Wnt5a/Ror2 signalingLRP6 expression promotes cancer cell proliferation and tumorigenesis by altering beta-catenin subcellular distributionDickkopfs and Wnt/β-catenin signalling in liver cancerWnt signaling in the murine diastemaDkkL1 (Soggy), a Dickkopf family member, localizes to the acrosome during mammalian spermatogenesis.Expression of the Wnt antagonist DKK3 is frequently suppressed in sporadic epithelial ovarian cancer.Dynamics and evolution of β-catenin-dependent Wnt signaling revealed through massively parallel clonogenic screening.Biomarkers in Osteosarcoma.Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal boneSox9 regulates hyperexpression of Wnt1 and Fzd1 in human osteosarcoma tissues and cells.Micro-RNA profiles in osteosarcoma as a predictive tool for ifosfamide response.Epigenetic silencing of the WNT antagonist Dickkopf 3 disrupts normal Wnt/β-catenin signalling and apoptosis regulation in breast cancer cellsAnalysis of Dickkopf3 interactions with Wnt signaling receptorsMicroRNA-34a inhibits the proliferation and metastasis of osteosarcoma cells both in vitro and in vivo.Overexpression of Dickkopf-3 induces apoptosis through mitochondrial pathway in human colon cancerWnt 5a signaling is critical for macrophage-induced invasion of breast cancer cell lines.The Wnt signaling pathway: implications for therapy in osteosarcoma.Targeting the giant cell tumor stromal cell: functional characterization and a novel therapeutic strategyUpregulated microRNA-92b regulates the differentiation and proliferation of EpCAM-positive fetal liver cells by targeting C/EBPß.Characterization of β-catenin expression in canine osteosarcomaPax6 regulates the expression of Dkk3 in murine and human cell lines, and altered responses to Wnt signaling are shown in FlpIn-3T3 cells stably expressing either the Pax6 or the Pax6(5a) isoform.Mesd is a general inhibitor of different Wnt ligands in Wnt/LRP signaling and inhibits PC-3 tumor growth in vivo.MicroRNA-29b-1 impairs in vitro cell proliferation, self‑renewal and chemoresistance of human osteosarcoma 3AB-OS cancer stem cells.A Comprehensive Overview of Skeletal Phenotypes Associated with Alterations in Wnt/β-catenin Signaling in Humans and Mice.DNA methylation status of REIC/Dkk-3 gene in human malignanciesThe role of Dickkopf-3 overexpression in esophageal adenocarcinomamiR-181c associates with tumor relapse of high grade osteosarcomaLoss of Dickkopf 3 Promotes the Tumorigenesis of Basal Breast Cancer.A novel FOXO1-mediated dedifferentiation blocking role for DKK3 in adrenocortical carcinogenesis.DKK3 blocked translocation of β-catenin/EMT induced by hypoxia and improved gemcitabine therapeutic effect in pancreatic cancer Bxpc-3 cell.Zebrafish Dkk3a protein regulates the activity of myf5 promoter through interaction with membrane receptor integrin α6bLRP5/6 in Wnt signaling and tumorigenesis.Chemotherapy resistance in osteosarcoma: current challenges and future directions.
P2860
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P2860
Dickkopf 3 inhibits invasion and motility of Saos-2 osteosarcoma cells by modulating the Wnt-beta-catenin pathway
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@ast
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@en
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@nl
type
label
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@ast
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@en
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@nl
prefLabel
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@ast
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@en
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@nl
P2093
P3181
P1433
P1476
Dickkopf 3 inhibits invasion a ...... g the Wnt-beta-catenin pathway
@en
P2093
Bang H Hoang
BethAnne Mazza
E Anders Kolb
John H Healey
Saminathan S Nathan
Tadahiko Kubo
P304
P3181
P356
10.1158/0008-5472.CAN-03-1952
P407
P577
2004-04-01T00:00:00Z