A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency
about
Congenital human thyroglobulin defect due to low expression of the thyroid-specific transcription factor TTF-1Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouseOver- and underdosage of SOX3 is associated with infundibular hypoplasia and hypopituitarismSyndromic short stature in patients with a germline mutation in the LIM homeobox LHX4.Targeted deletion of the mouse POU domain gene Brn-3a causes selective loss of neurons in the brainstem and trigeminal ganglion, uncoordinated limb movement, and impaired sucklingFunctional characterization of a human POU1F1 mutation associated with isolated growth hormone deficiency: a novel etiology for IGHDPitx factors are involved in basal and hormone-regulated activity of the human prolactin promoterA PIT-1 homeodomain mutant blocks the intranuclear recruitment of the CCAAT/enhancer binding protein alpha required for prolactin gene transcriptionThe opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domainNeutral sphingomyelinase 2 (smpd3) in the control of postnatal growth and developmentMagnetic resonance imaging of the hypothalamus-pituitary unit in childrensuspected of hypopituitarism: who, how and when toinvestigate.Genetic regulation of pituitary gland development in human and mousePROP1 gene mutations in a 36-year-old female presenting with psychosisDmrt5 controls corticotrope and gonadotrope differentiation in the zebrafish pituitary.Research resource: A genome-wide study identifies potential new target genes for POU1F1A highly selective, label-free, homogenous luminescent switch-on probe for the detection of nanomolar transcription factor NF-kappaB.Contributions of immunohistochemistry and in situ hybridization to the functional analysis of pituitary adenomas.Genetic aspects of central hypothyroidism.The molecular basis for developmental disorders of the pituitary gland in man.Aged PROP1 deficient dwarf mice maintain ACTH production.Cellular and molecular specificity of pituitary gland physiology.An intestine-specific homeobox gene regulates proliferation and differentiation.Missense mutations of human homeoboxes: A review.Gradual loss of ACTH due to a novel mutation in LHX4: comprehensive mutation screening in Japanese patients with congenital hypopituitarismGenetic disorders of human growth.A single base difference between Pit-1 binding sites at the hGH promoter and locus control region specifies distinct Pit-1 conformations and functionsRequired enhancer-matrin-3 network interactions for a homeodomain transcription program.Central hypothyroidismDose-dependent dual role of PIT-1 (POU1F1) in somatolactotroph cell proliferation and apoptosisX-linked recessive panhypopituitarism associated with a regional duplication in Xq25-q26.Advances in endocrinologyHuman and mouse TPIT gene mutations cause early onset pituitary ACTH deficiencyComparative genomics reveals functional transcriptional control sequences in the Prop1 gene.A soluble transcription factor, Oct-1, is also found in the insoluble nuclear matrix and possesses silencing activity in its alanine-rich domain.Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function.A novel POU domain protein which binds to the T-cell receptor beta enhancer.The role of transcription factors implicated in anterior pituitary development in the aetiology of congenital hypopituitarism.Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation.Vertical transmission of hypopituitarism: critical importance of appropriate interpretation of thyroid function tests and levothyroxine therapy during pregnancy.Regulation of striatal D1A dopamine receptor gene transcription by Brn-4
P2860
Q24322048-750695B7-2B70-4E6B-B0C7-D6DAE901B4BAQ24323305-D2A950C9-51E9-4495-B431-4A81B4F08FEBQ24531513-30D67648-BD2B-4356-9D13-52BCC25FCA24Q24536132-41F6F679-FA1D-446F-A1CE-CA0EE74E8361Q24602910-FE6FF1A1-F5D6-49ED-A622-052966534898Q28118827-03146E2D-570C-4AEB-A3A1-107F57848259Q28201214-B0AF1689-EEB0-4FD1-866E-7B490BFEC707Q28580127-F34C74DF-2299-4CA2-8A56-819031C67C63Q28590437-527834B2-5A08-403A-893F-7271B202D15CQ28595054-C26DD8B6-0877-4242-94AA-40447A7809C6Q30947967-434EC23B-9253-4A2F-B363-0E46C75A404BQ33590141-997A8E4D-A382-4D32-8779-72228ABF1D7DQ33601614-50C467FA-53BD-4E62-AFCE-E48349685C0AQ33631780-5EEA98CA-7D79-4A88-9387-1860D4AA51D4Q33636348-F9878B35-BBC5-4881-864C-EA2AC761873FQ33844628-7C399F64-564D-4999-B7BB-4AA6C3CEC715Q33869195-CC93A262-DFD6-461A-B09D-DEEDBF4C923DQ33912502-BD5852FE-EB5F-44E2-BEF4-46A9CD5109AFQ33942188-D67D75B0-673A-4080-BA1D-0AAE6263674EQ34092471-4300E761-F83F-486A-9C5A-65A46D545284Q34251305-8118FB94-FB2F-456F-A552-39AC8C24C23BQ34370444-FD6183BA-4D2B-4B3A-B8EE-E66521A4BA01Q34415477-F6C223F4-8C12-499B-95CD-891120D86FCCQ34430600-D0F63FB6-0C45-4E36-BC29-FBDA42D3FB5CQ34716062-D12E180F-B192-417B-A88E-07BC80115CCBQ35071190-16211832-4BCD-4531-B8B3-7DB8C27DDF9AQ35174629-3C8D9C67-61D8-4A9D-8563-639899D2D2FDQ35205084-E497AF0E-D224-46B6-A50A-3FF92B9EE259Q35231490-68A372F7-3C36-488E-967D-81A845DC107BQ35238594-AFC3A05F-A95E-4B41-9874-AA87F772D72DQ35258844-BE05F7A1-70DF-454F-94D1-5B408FE9F8D0Q35964450-98FF33B7-AB51-4442-A9A5-A9E067D210ACQ36021378-20DB04AE-CE34-4FF7-B003-9438FA691E0BQ36561509-E62240D8-006F-4218-B5ED-0D0361C3631DQ36719053-6F7B43EF-ACC3-43FB-8624-7592252A5C98Q36741717-5E88292B-04D0-4CDA-A924-2758832974A4Q36793669-EB937F3B-641B-4ADF-9D14-1082BC364AE9Q36860297-4204E26C-D326-4C3E-BC2D-8CD16B14FF6EQ36991102-CB4278D6-AF24-4F66-BD50-025B94659A76Q37275396-9174AAA6-B1EA-443F-B9F1-5F2BF1E6864A
P2860
A mutation in the POU-homeodomain of Pit-1 responsible for combined pituitary hormone deficiency
description
1992 nî lūn-bûn
@nan
1992 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@ast
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@en
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@nl
type
label
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@ast
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@en
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@nl
prefLabel
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@ast
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@en
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@nl
P2093
P1433
P1476
A mutation in the POU-homeodom ...... d pituitary hormone deficiency
@en
P2093
P304
P356
10.1126/SCIENCE.257.5073.1115
P407
P577
1992-08-21T00:00:00Z