An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain
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An atomic model for the pleated beta-sheet structure of abeta amyloid protofilamentsPrion, amyloid beta-derived Cu(II) ions, or free Zn(II) ions support S-nitroso-dependent autocleavage of glypican-1 heparan sulfateEffect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revisedModelling neuroinflammatory phenotypes in vivoGlycosaminoglycans and glycomimetics in the central nervous systemInteraction between Alzheimer's disease beta A4 precursor protein (APP) and the extracellular matrix: evidence for the participation of heparan sulfate proteoglycansAgrin in Alzheimer's disease: altered solubility and abnormal distribution within microvasculature and brain parenchymaOptical microscopy of growing insulin amyloid spherulites on surfaces in vitro.The formation of spherulites by amyloid fibrils of bovine insulin.Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide.Spherulites of amyloid-beta42 in vitro and in Alzheimer's diseaseMonoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptideAlpha-synuclein in Lewy body disease and Alzheimer's disease.Cellular cofactors for amyloid beta-peptide-induced cell stress. Moving from cell culture to in vivo.In vivo fragmentation of heparan sulfate by heparanase overexpression renders mice resistant to amyloid protein A amyloidosisApolipoprotein E, smooth muscle cells and the pathogenesis of cerebral amyloid angiopathy: the potential role of impaired cerebrovascular A beta clearance.Mechanisms of cerebrovascular amyloid deposition. Lessons from mouse models.Heparin oligosaccharides as potential therapeutic agents in senile dementiaA critique of the drug discovery and phase 3 clinical programs targeting the amyloid hypothesis for Alzheimer disease.Neuroprotective effects of garlic a review.Heparin nanoparticles for β amyloid binding and mitigation of β amyloid associated cytotoxicity.Modulators of axonal growth and guidance at the brain midline with special reference to glial heparan sulfate proteoglycans.Amyloidogenesis: historical and modern observations point to heparan sulfate proteoglycans as a major culprit.Altered presynaptic protein NACP is associated with plaque formation and neurodegeneration in Alzheimer's diseaseSelective binding of soluble Abeta1-40 and Abeta1-42 to a subset of senile plaques.In Alzheimer's disease the Golgi apparatus of a population of neurons without neurofibrillary tangles is fragmented and atrophic.Agrin is a major heparan sulfate proteoglycan accumulating in Alzheimer's disease brain.Chronic overproduction of transforming growth factor-beta1 by astrocytes promotes Alzheimer's disease-like microvascular degeneration in transgenic miceChemical and immunological heterogeneity of fibrillar amyloid in plaques of Alzheimer's disease and Down's syndrome brains revealed by confocal microscopy.Astroglial expression of human alpha(1)-antichymotrypsin enhances alzheimer-like pathology in amyloid protein precursor transgenic mice.Pathogenic factors in vascular dementia and Alzheimer's disease. Multiple actions of heparin that probably are beneficial.Amyloid accomplices and enforcersAmyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease.Mitochondrial dysfunction and Alzheimer's disease: role of amyloid-beta peptide alcohol dehydrogenase (ABAD).Signaling pathways regulating neuron-glia interaction and their implications in Alzheimer's disease.Increased Aβ pathology in aged Tg2576 mice born to mothers fed a high fat dietDisease modifying therapy for AD?In vivo diffusion of lactoferrin in brain extracellular space is regulated by interactions with heparan sulfate.Heat shock proteins and amateur chaperones in amyloid-Beta accumulation and clearance in Alzheimer's disease.Nanoimaging in protein-misfolding and -conformational diseases.
P2860
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P2860
An important role of heparan sulfate proteoglycan (Perlecan) in a model system for the deposition and persistence of fibrillar A beta-amyloid in rat brain
description
1994 nî lūn-bûn
@nan
1994 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
An important role of heparan s ...... ar A beta-amyloid in rat brain
@ast
An important role of heparan s ...... ar A beta-amyloid in rat brain
@en
An important role of heparan s ...... ar A beta-amyloid in rat brain
@nl
type
label
An important role of heparan s ...... ar A beta-amyloid in rat brain
@ast
An important role of heparan s ...... ar A beta-amyloid in rat brain
@en
An important role of heparan s ...... ar A beta-amyloid in rat brain
@nl
prefLabel
An important role of heparan s ...... ar A beta-amyloid in rat brain
@ast
An important role of heparan s ...... ar A beta-amyloid in rat brain
@en
An important role of heparan s ...... ar A beta-amyloid in rat brain
@nl
P2093
P1433
P1476
An important role of heparan s ...... ar A beta-amyloid in rat brain
@en
P2093
A Mizutani
D G Morgan
R Sekiguchi
W A Schreier
P304
P356
10.1016/0896-6273(94)90165-1
P407
P577
1994-01-01T00:00:00Z