The war against influenza: discovery and development of sialidase inhibitors
about
Capnocytophaga canimorsus: a human pathogen feeding at the surface of epithelial cells and phagocytesA generic system for the expression and purification of soluble and stable influenza neuraminidaseNeuraminidase Inhibitors from the Culture Broth of Phellinus linteusPeramivir: A Novel Intravenous Neuraminidase Inhibitor for Treatment of Acute Influenza InfectionsGrowing with dinosaurs: natural products from the Cretaceous relict Metasequoia glyptostroboides Hu & Cheng—a molecular reservoir from the ancient world with potential in modern medicineSialidases from gut bacteria: a mini-reviewViruses and sialic acids: rules of engagementRecent progress in structure-based anti-influenza drug designSialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regenerationStructure of anEscherichia coli N-acetyl-D-neuraminic acid lyase mutant, E192N, in complex with pyruvate at 1.45 Å resolutionThe 2009 pandemic H1N1 neuraminidase N1 lacks the 150-cavity in its active siteNovel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase.Influenza A Virus N5 Neuraminidase Has an Extended 150-CavityStructural and functional characterization of neuraminidase-like molecule N10 derived from bat influenza A virusStructural and Functional Analysis of Laninamivir and its Octanoate Prodrug Reveals Group Specific Mechanisms for Influenza NA InhibitionThe Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water DynamicsInduced opening of influenza virus neuraminidase N2 150-loop suggests an important role in inhibitor bindingSelective inhibition of Biotin Protein Ligase from Staphylococcus aureusSynthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibilityMechanism-based covalent neuraminidase inhibitors with broad-spectrum influenza antiviral activityStructure of Influenza Virus N7: the Last Piece of the Neuraminidase"Jigsaw"PuzzlePolyhydroyxalkanoate synthase fusions as a strategy for oriented enzyme immobilisation.Synthesis, structure and inhibitory activity of a stereoisomer of oseltamivir carboxylateTuning mechanism-based inactivators of neuraminidases: mechanistic and structural insightsTracing binding modes in hit-to-lead optimization: chameleon-like poses of aspartic protease inhibitorsTwo birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicinePlasticity of 150-loop in influenza neuraminidase explored by Hamiltonian replica exchange molecular dynamics simulationsThe influence of 150-cavity binders on the dynamics of influenza A neuraminidases as revealed by molecular dynamics simulations and combined clusteringLocking the 150-cavity open: in silico design and verification of influenza neuraminidase inhibitorsThe Mechanism by which 146-N-Glycan Affects the Active Site of NeuraminidaseDesialylation of airway epithelial cells during influenza virus infection enhances pneumococcal adhesion via galectin bindingInsight into a molecular interaction force supporting peptide backbones and its implication to protein loops and foldingThe use of glycoinformatics in glycochemistryIota-carrageenan is a potent inhibitor of influenza A virus infectionProgress of small molecular inhibitors in the development of anti-influenza virus agents.Molecular distribution of amino acid substitutions on neuraminidase from the 2009 (H1N1) human influenza pandemic virus.In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus.From neuraminidase inhibitors to conjugates: a step towards better anti-influenza drugs?Combination effects of peramivir and favipiravir against oseltamivir-resistant 2009 pandemic influenza A(H1N1) infection in mice.Drug Repurposing Identifies Inhibitors of Oseltamivir-Resistant Influenza Viruses
P2860
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P2860
The war against influenza: discovery and development of sialidase inhibitors
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
The war against influenza: discovery and development of sialidase inhibitors
@ast
The war against influenza: discovery and development of sialidase inhibitors
@en
The war against influenza: discovery and development of sialidase inhibitors
@nl
type
label
The war against influenza: discovery and development of sialidase inhibitors
@ast
The war against influenza: discovery and development of sialidase inhibitors
@en
The war against influenza: discovery and development of sialidase inhibitors
@nl
prefLabel
The war against influenza: discovery and development of sialidase inhibitors
@ast
The war against influenza: discovery and development of sialidase inhibitors
@en
The war against influenza: discovery and development of sialidase inhibitors
@nl
P3181
P356
P1476
The war against influenza: discovery and development of sialidase inhibitors
@en
P2093
Mark von Itzstein
P2888
P304
P3181
P356
10.1038/NRD2400
P407
P577
2007-12-01T00:00:00Z