Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
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MYC, Metabolism, and CancerTargeted Disruption of the Interaction Between WD-40 Repeat Protein 5 (WDR5) and Mixed Lineage Leukemia (MLL)/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase ComplexesOmoMYC blunts promoter invasion by oncogenic MYC to inhibit gene expression characteristic of MYC-dependent tumorsThe MYC-WDR5 Nexus and CancerChromNet: Learning the human chromatin network from all ENCODE ChIP-seq data.MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myelomaMenin enhances c-Myc-mediated transcription to promote cancer progressionc-Myc is Required for BRAFV600E-Induced Epigenetic Silencing by H3K27me3 in Tumorigenesis.Epigenetics: Disrupting histone lysine methylation.Genomic Determinants of THAP11/ZNF143/HCFC1 Complex Recruitment to Chromatin.BPTF is required for c-MYC transcriptional activity and in vivo tumorigenesis.The T-Box factor TBX3 is important in S-phase and is regulated by c-Myc and cyclin A-CDK2Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motifc-MYC partners with BPTF in human cancer.Different promoter affinities account for specificity in MYC-dependent gene regulation.Linking long non-coding RNAs and SWI/SNF complexes to chromatin remodeling in cancer.Chromatin remodeling and bivalent histone modifications in embryonic stem cells.Sequence-specific DNA binding by MYC/MAX to low-affinity non-E-box motifs.MYC, Metabolic Synthetic Lethality, and Cancer.MYC-Master Regulator of the Cancer Epigenome and Transcriptome.Immunotherapy and Targeted Therapy for Small Cell Lung Cancer: There Is Hope.MYC Modulation around the CDK2/p27/SKP2 AxisFamily matters: How MYC family oncogenes impact small cell lung cancer.Small molecules remain on target for c-Myc.Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.PAF1 complex component Leo1 helps recruit Drosophila Myc to promoters.Moonlighting with WDR5: A Cellular Multitasker.Chromatin dependencies in cancer and inflammation.MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human Cancer.Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.The KDM4A/KDM4C/NF-κB and WDR5 epigenetic cascade regulates the activation of B cells.WDR5 supports colon cancer cells by promoting methylation of H3K4 and suppressing DNA damage.Hijacking a key chromatin modulator creates epigenetic vulnerability for MYC-driven cancerMYC dephosphorylation by the PP1/PNUTS phosphatase complex regulates chromatin binding and protein stability
P2860
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P2860
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
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2015 nî lūn-bûn
@nan
2015 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@ast
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@en
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@nl
type
label
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@ast
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@en
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@nl
prefLabel
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@ast
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@en
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@nl
P2093
P2860
P50
P3181
P1433
P1476
Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC
@en
P2093
Audra M Foshage
Bethany Alicie
Bryan Cawthon
Christine M Eischen
Edward T Olejniczak
Gregory C Howard
Jason Phan
Kevin C Ess
Lance R Thomas
P2860
P304
P3181
P356
10.1016/J.MOLCEL.2015.02.028
P407
P577
2015-03-26T00:00:00Z