Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells
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The mitochondrial Ca2+ uniporter MCU is essential for glucose-induced ATP increases in pancreatic β-cellsCloning and functional characterization of a novel ATP-sensitive potassium channel ubiquitously expressed in rat tissues, including pancreatic islets, pituitary, skeletal muscle, and heartATP-sensitive potassium channel and bursting in the pancreatic beta cell. A theoretical study.Biophysical properties of gap junctions between freshly dispersed pairs of mouse pancreatic beta cells.Kir6.2 is required for adaptation to stress.How ATP inhibits the open K(ATP) channelAnti-CD38 autoantibodies in type? diabetesIdentification of a chemical probe for NAADP by virtual screeningTargeting microglial K(ATP) channels to treat neurodegenerative diseases: a mitochondrial issueDefective interactions of protein partner with ion channels and transporters as alternative mechanisms of membrane channelopathiesEpisodic hormone secretion: a comparison of the basis of pulsatile secretion of insulin and GnRH.A fresh view of glycolysis and glucokinase regulation: history and current statusKATP channels and cardiovascular disease: suddenly a syndromeNeuroprotective role of ATP-sensitive potassium channels in cerebral ischemiaSignaling mechanisms of glucose-induced F-actin remodeling in pancreatic islet β cellsAction potentials and insulin secretion: new insights into the role of Kv channels.Converging roles of ion channels, calcium, metabolic stress, and activity pattern of Substantia nigra dopaminergic neurons in health and Parkinson's diseaseAssembly limits the pharmacological complexity of ATP-sensitive potassium channelsInsulin-releasing properties of the frog skin peptide pseudin-2 and its [Lys18]-substituted analogueEffects of 2-ketoisocaproate on insulin release and single potassium channel activity in dispersed rat pancreatic beta-cellsSynthesis and characterization of a quinolinonic compound activating ATP-sensitive K(+) channels in endocrine and smooth muscle tissuesNADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretionRapid insulinotropic action of low doses of bisphenol-A on mouse and human islets of Langerhans: role of estrogen receptor βFunctional characterization of mouse sodium/glucose transporter type 3bOcular Hypotensive Effects of the ATP-Sensitive Potassium Channel Opener Cromakalim in Human and Murine Experimental Model SystemsSpecificity in beta cell expression of L-3-hydroxyacyl-CoA dehydrogenase, short chain, and potential role in down-regulating insulin releaseExpression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cellsClass A calcium channel variants in pancreatic islets and their role in insulin secretionTRPM4 controls insulin secretion in pancreatic beta-cellsGenetic variations in magnesium-related ion channels may affect diabetes risk among African American and Hispanic American womenChannels in mitochondrial membranes: knowns, unknowns, and prospects for the future.The ATP-sensitive K(+)-channel (K(ATP)) controls early left-right patterning in Xenopus and chick embryos.Different metabolic responses in alpha-, beta-, and delta-cells of the islet of Langerhans monitored by redox confocal microscopy.Clinical and molecular data from 61 Brazilian cases of Congenital Hyperinsulinemic Hypoglycemia.Monitoring of exocytosis and endocytosis of insulin secretory granules in the pancreatic beta-cell line MIN6 using pH-sensitive green fluorescent protein (pHluorin) and confocal laser microscopyATP-sensitive K+ channels that are blocked by hypoglycemia-inducing sulfonylureas in insulin-secreting cells are activated by galanin, a hyperglycemia-inducing hormoneGalanin activates nucleotide-dependent K+ channels in insulin-secreting cells via a pertussis toxin-sensitive G-protein.Structure, function and regulation of pyruvate carboxylase.Rapid regulation of K(ATP) channel activity by 17{beta}-estradiol in pancreatic {beta}-cells involves the estrogen receptor {beta} and the atrial natriuretic peptide receptor.Constitutive endocytic recycling and protein kinase C-mediated lysosomal degradation control K(ATP) channel surface density
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P2860
Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells
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article publié dans la revue scientifique Nature
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artículu científicu
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scientific article
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wetenschappelijk artikel
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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P2093
P356
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Glucose induces closure of sin ...... ated rat pancreatic beta-cells
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P2093
D E Harrison
F M Ashcroft
S J Ashcroft
P2888
P356
10.1038/312446A0
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P6179
1016843282