ATP-sensitive K+ channels that are blocked by hypoglycemia-inducing sulfonylureas in insulin-secreting cells are activated by galanin, a hyperglycemia-inducing hormone
about
Isolation and primary structure of pituitary human galanin, a 30-residue nonamidated neuropeptideMolecular cloning of a functional human galanin receptorMechanisms of inhibition of insulin release.K+ channel openers activate brain sulfonylurea-sensitive K+ channels and block neurosecretion.Galanin is an estrogen-inducible, secretory product of the rat anterior pituitaryRegulation of ATP-sensitive K+ channels in insulinoma cells: activation by somatostatin and protein kinase C and the role of cAMP.Leptin acts via lateral hypothalamic area neurotensin neurons to inhibit orexin neurons by multiple GABA-independent mechanisms.N-terminal galanin-(1-16) fragment is an agonist at the hippocampal galanin receptorEssential role of adenosine, adenosine A1 receptors, and ATP-sensitive K+ channels in cerebral ischemic preconditioning.Regulation of glucose and insulin release following acute and repeated treatment with the synthetic galanin analog NAX-5055Impulse flow dependency of galanin release in vivo in the rat ventral hippocampus.Activators of protein kinase C depolarize insulin-secreting cells by closing K+ channels.ATP-modulated K+ channels sensitive to antidiabetic sulfonylureas are present in adenohypophysis and are involved in growth hormone release.Purification of a galanin receptor from pig brain.Amylin modulates beta-cell glucose sensing via effects on stimulus-secretion coupling.Galanin.Electrophysiological evidence for a hyperpolarizing, galanin (1-15)-selective receptor on hippocampal CA3 pyramidal neuronsGalanin inhibits a dihydropyridine-sensitive Ca2+ current in the RINm5f cell line.Subunit composition of G(o) proteins functionally coupling galanin receptors to voltage-gated calcium channels.Inhibition of adenylate cyclase activity by galanin in rat insulinoma cells is mediated by the G-protein Gi3.Roles for Orexin/Hypocretin in the Control of Energy Balance and Metabolism.Vasopressin directly closes ATP-sensitive potassium channels evoking membrane depolarization and an increase in the free intracellular Ca2+ concentration in insulin-secreting cells.Adrenaline-, not somatostatin-induced hyperpolarization is accompanied by a sustained inhibition of insulin secretion in INS-1 cells. Activation of sulphonylurea K+ATP channels is not involved.Characterization of the solubilized glibenclamide receptor in a hamster pancreatic beta-cell line, HIT T15.Galanin evokes a cytosolic calcium bursting mode and hormone release in GH3/B6 pituitary cells.Extracellular ATP increases cytoplasmic free Ca2+ concentration in clonal insulin-producing RINm5F cells. A mechanism involving direct interaction with both release and refilling of the inositol 1,4,5-trisphosphate-sensitive Ca2+ pool.The action of diazoxide and minoxidil sulphate on rat blood vessels: a comparison with cromakalim.Cultured astrocytes express functional receptors for galanin.Effect of K+ channel-modulating drugs on the vasoconstrictor responses of leukotrienes C4, D4 and angiotensin II in the guinea-pig isolated perfused heart.Epinephrine-induced hyperpolarization of islet cells without KATP channels.Effect of galanin on glucose-, arginine-, or potassium-stimulated insulin release.Oscillations of membrane potential and cytosolic Ca(2+) concentration in SUR1(-/-) beta cells.Galanin modulates neuronal and synaptic properties in the rat supraoptic nucleus in a use and state dependent manner.A facile label-free aptasensor for detecting ATP based on fluorescence enhancement of poly(thymine)-templated copper nanoparticles.Adrenergic and nonadrenergic cotransmitters inhibit insulin secretion during sympathetic stimulation in dogs.ATP-sensitive K(+) Channels in the Regulation of Feeding Behavior: A Hypothesis.
P2860
Q24293120-8B0ACD22-4719-4BC2-BCAA-ADF71F57165BQ24306226-38874B8F-FB78-49B7-AAFB-B321AF5C9A05Q27867698-6A0B1DE1-8905-4DDC-91E7-1B92721AC2F6Q33567689-8ABF2BB3-F6D3-4806-8EDC-1810E7D4A198Q33653199-31BC4FF6-9DD0-4810-A31F-4ECD2071D173Q33851631-8FEE0B54-1174-42AE-BB39-A00F552DA4A6Q34067371-89DB9634-CF61-47F5-8002-887448FF75F9Q34324213-B6A3CEDA-3614-43CC-A77C-A807F381EBCFQ34357041-2FD2C6C5-415B-4A7C-AAD3-0E9BEF45410CQ35478083-9CCF5104-688C-474B-94B2-E54573C9EDE6Q35679330-184E2654-4400-4860-BC1E-B10D1806B3A3Q36063235-6B71B310-DE93-4168-9996-9271E3B8AFBEQ36102890-1824FA3B-15A2-4D92-BE29-F3856C36DA01Q36267074-83CA75FB-CFDA-40B7-B149-8A5F02C949FEQ36575059-A603204C-A2F7-4775-9C31-E8D6DED3529DQ36707596-9056ED0F-1D38-48B8-BF79-E01B6834831DQ36749642-F05CD475-5D91-46D0-B881-567D387EDBDFQ37601277-93FE4DFE-774F-4656-B121-6ADF4C47E521Q38290682-EF22D98C-0052-42CB-8C3C-DA3D6F2980A7Q38303430-52CF8840-85EC-4548-8EE2-7B2B0C406088Q39026723-D673DA4B-ED02-4596-A61F-EC859DA721FFQ40822175-6545776B-A244-4F65-ABD5-7F6599C1CA05Q41202111-7ADABAB6-EA18-467E-8C26-42B45AED7D44Q41671011-972B9E54-A5B6-4181-87AD-F9D7FBE636BCQ41710916-4893DE76-3B07-4477-868B-9253F0E12D1DQ41748616-48208ED3-A356-4CB7-9AED-6748853943D5Q41946250-28C380C0-440B-401E-A8F0-CC4DD69A956CQ42462555-2CC6A4A3-AE42-4816-8B58-8841192EDE8DQ42712128-C15021A9-91FB-4645-BD70-B66F4D73CC0DQ44653222-95566637-AF51-41AF-A6DE-BF36FA04C3F9Q44691186-3D8D7AD9-24BF-4629-8936-539F01CEC43FQ44762040-5D9AA901-041C-420E-A300-3DA261B0F3E0Q48586005-9F08983B-DD66-4A8D-B2FC-4154F157244EQ51232099-5FA17331-3227-4DF3-85D3-971148F0BAE3Q54062692-26821C38-E2FE-4D55-AB17-38289F65146AQ54173930-CD2DD1E9-FAF8-4422-AE9F-8662F9C04B8D
P2860
ATP-sensitive K+ channels that are blocked by hypoglycemia-inducing sulfonylureas in insulin-secreting cells are activated by galanin, a hyperglycemia-inducing hormone
description
1988 nî lūn-bûn
@nan
1988 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
ATP-sensitive K+ channels that ...... hyperglycemia-inducing hormone
@ast
ATP-sensitive K+ channels that ...... hyperglycemia-inducing hormone
@en
ATP-sensitive K+ channels that ...... yperglycemia-inducing hormone.
@nl
type
label
ATP-sensitive K+ channels that ...... hyperglycemia-inducing hormone
@ast
ATP-sensitive K+ channels that ...... hyperglycemia-inducing hormone
@en
ATP-sensitive K+ channels that ...... yperglycemia-inducing hormone.
@nl
prefLabel
ATP-sensitive K+ channels that ...... hyperglycemia-inducing hormone
@ast
ATP-sensitive K+ channels that ...... hyperglycemia-inducing hormone
@en
ATP-sensitive K+ channels that ...... yperglycemia-inducing hormone.
@nl
P2093
P2860
P921
P356
P1476
ATP-sensitive K+ channels that ...... hyperglycemia-inducing hormone
@en
P2093
Lazdunski M
Schmid-Antomarchi H
de Weille J
P2860
P304
P356
10.1073/PNAS.85.4.1312
P407
P577
1988-02-01T00:00:00Z