The Ia molecule of the antigen-presenting cell plays a critical role in immune response gene regulation of T cell activation
about
Structure of miniature swine class II DRB genes: conservation of hypervariable amino acid residues between distantly related mammalian speciesX-box-binding proteins positively and negatively regulate transcription of the HLA-DRA gene through interaction with discrete upstream W and V elements.Defects in antigen presentation of mutant influenza haemagglutinins are reversed by mutations in the MHC class II moleculeUncovering the role of invariant chain in controlling MHC class II antigen capture.Identification of functional regions on the I-Ab molecule by site-directed mutagenesis.Structural basis of antigen recognition by T lymphocytes. Implications for vaccines.Interaction between a "processed" ovalbumin peptide and Ia moleculesAntigenic competition at the level of peptide-Ia bindingFrom Immunity and Vaccines to Mammalian RegenerationInhibition of antigen-specific T lymphocyte activation by structurally related Ir gene-controlled polymers. II. Competitive inhibition of I-E-restricted, antigen-specific T cell responsesT cell tolerance studied at the level of antigenic determinants. I. Latent reactivity to lysozyme peptides that lack suppressogenic epitopes can be revealed in lysozyme-tolerant miceIdentification, at the genomic level, of an HLA-DR restriction element for cloned antigen-specific T4 cells.Distinct recognition phenotypes exist for T cell clones specific for small peptide regions of proteins. Implications for the mechanisms underlying major histocompatibility complex-restricted antigen recognition and clonal deletion models of immune rDirect evidence that a class II molecule and a simple globular protein generate multiple determinantsI-A-restricted T cell antigen recognition. Analysis of the roles of A alpha and A beta using DNA-mediated gene transfer.The cytotoxic T cell response to the male-specific histocompatibility antigen (H-Y) is controlled by two dominant immune response genes, one in the MHC, the other in the Tar alpha-locusNonoverlapping T and B cell determinants on an hepatitis B surface antigen pre-S(2) region synthetic peptide.Ia molecule-associated selectivity in T cell recognition of a 23-amino-acid peptide of lysozyme.Overlapping T cell antigenic sites on a synthetic peptide fragment from herpes simplex virus glycoprotein D, the degenerate MHC restriction elicited, and functional evidence for antigen-Ia interactionReconstruction of the immunogenic peptide RNase(43-56) by identification and transfer of the critical residues into an unrelated peptide backbone.Analysis of peptide binding patterns in different major histocompatibility complex/T cell receptor complexes using pigeon cytochrome c-specific T cell hybridomas. Evidence that a single peptide binds major histocompatibility complex in different conPhotoaffinity labeling demonstrates binding between Ia molecules and nominal antigen on antigen-presenting cells.T-cell activation by peptide antigen: effect of peptide sequence and method of antigen presentationAntigen conformation determines processing requirements for T-cell activation.Rearrangement and transcription of a T-cell receptor beta-chain gene in different T-cell subsetsAcquired immunological tolerance of foreign cells is impaired by recombinant interleukin 2 or vitamin A acetate.Predicted protein sequence of the murine I-E-beta S-polypeptide chain from cDNA and genomic clones
P2860
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P2860
The Ia molecule of the antigen-presenting cell plays a critical role in immune response gene regulation of T cell activation
description
1983 nî lūn-bûn
@nan
1983 թուականին հրատարակուած գիտական յօդուած
@hyw
1983 թվականին հրատարակված գիտական հոդված
@hy
1983年の論文
@ja
1983年論文
@yue
1983年論文
@zh-hant
1983年論文
@zh-hk
1983年論文
@zh-mo
1983年論文
@zh-tw
1983年论文
@wuu
name
The Ia molecule of the antigen ...... egulation of T cell activation
@ast
The Ia molecule of the antigen ...... egulation of T cell activation
@en
The Ia molecule of the antigen ...... egulation of T cell activation
@nl
type
label
The Ia molecule of the antigen ...... egulation of T cell activation
@ast
The Ia molecule of the antigen ...... egulation of T cell activation
@en
The Ia molecule of the antigen ...... egulation of T cell activation
@nl
prefLabel
The Ia molecule of the antigen ...... egulation of T cell activation
@ast
The Ia molecule of the antigen ...... egulation of T cell activation
@en
The Ia molecule of the antigen ...... egulation of T cell activation
@nl
P2093
P1476
The Ia molecule of the antigen ...... egulation of T cell activation
@en
P2093
D Hansburg
E Heber-Katz
R H Schwartz
P407
P577
1983-01-01T00:00:00Z