Secretin and vasoactive intestinal peptide receptors: members of a unique family of G protein-coupled receptors
about
Molecular basis of association of receptor activity-modifying protein 3 with the family B G protein-coupled secretin receptorMolecular mechanism of pancreatic and salivary gland fluid and HCO3 secretionIdentification of key residues for interaction of vasoactive intestinal peptide with human VPAC1 and VPAC2 receptors and development of a highly selective VPAC1 receptor agonist. Alanine scanning and molecular modeling of the peptideVPAC receptors for VIP and PACAPMolecular pharmacology of the secretin receptorLower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout miceETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamilyDifferent actions of secretin and Gly-extended secretin predict secretin receptor subtypesPancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and massMolecular cloning and functional expression of a VIP-specific receptor.The human vasoactive intestinal peptide/pituitary adenylate cyclase-activating peptide receptor 1 (VPAC1) promoter: characterization and role in receptor expression during enterocytic differentiation of the colon cancer cell line Caco-2Cl.20Evolution of secretin family GPCR members in the metazoa.Secretin receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway.UVB-induced gene expression in the skin of Xiphophorus maculatus Jp 163 B.Refinement of the pharmacophore of an agonist ligand of the secretin receptor using conformationally constrained cyclic hexapeptides.Seven transmembrane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery.Origin of secretin receptor precedes the advent of tetrapoda: evidence on the separated origins of secretin and orexinEnhancing the GLP-1 receptor signaling pathway leads to proliferation and neuroprotection in human neuroblastoma cells.Human VPAC1 receptor selectivity filter. Identification of a critical domain for restricting secretin binding.Elucidation of the active conformation of the amino terminus of receptor-bound secretin using intramolecular disulfide bond constraints.Regulation of cholangiocyte bicarbonate secretion.Importance of each residue within secretin for receptor binding and biological activitySecretin inhibits cholangiocarcinoma growth via dysregulation of the cAMP-dependent signaling mechanisms of secretin receptor.Mechanism involved in Danshen-induced fluid secretion in salivary glands.Molecular basis of secretin docking to its intact receptor using multiple photolabile probes distributed throughout the pharmacophoreCross-regulation of VPAC2 receptor internalization by m2 receptors via c-Src-mediated phosphorylation of GRK2.Receptor oligomerization in family B1 of G-protein-coupled receptors: focus on BRET investigations and the link between GPCR oligomerization and binding cooperativity.Ligand binding and activation of the secretin receptor, a prototypic family B G protein-coupled receptor.Management of sub-5 mm rectal carcinoids with lymph node metastases.Use of Cysteine Trapping to Map Spatial Approximations between Residues Contributing to the Helix N-capping Motif of Secretin and Distinct Residues within Each of the Extracellular Loops of Its Receptor.Secretin receptor-deficient mice exhibit impaired synaptic plasticity and social behavior.Cholangiocyte proliferation and liver fibrosis.Spatial approximation between secretin residue five and the third extracellular loop of its receptor provides new insight into the molecular basis of natural agonist binding.Molecular cloning and characterization of two pig vasoactive intestinal polypeptide receptors (VPAC1-R and VPAC2-R).Physiological parameters governing the action of pancreatic lipase.The orthosteric agonist-binding pocket in the prototypic class B G-protein-coupled secretin receptor.Vasoactive intestinal peptide upregulates MUC2 intestinal mucin via CREB/ATF1.Secretin activation of chromogranin A gene transcription. Identification of the signaling pathways in cis and in trans.Secretin receptors in normal and diseased human pancreas: marked reduction of receptor binding in ductal neoplasiaSecretin receptor involvement in prion-infected cells and animals.
P2860
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P2860
Secretin and vasoactive intestinal peptide receptors: members of a unique family of G protein-coupled receptors
description
1998 nî lūn-bûn
@nan
1998 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Secretin and vasoactive intest ...... of G protein-coupled receptors
@ast
Secretin and vasoactive intest ...... of G protein-coupled receptors
@en
Secretin and vasoactive intest ...... of G protein-coupled receptors
@nl
type
label
Secretin and vasoactive intest ...... of G protein-coupled receptors
@ast
Secretin and vasoactive intest ...... of G protein-coupled receptors
@en
Secretin and vasoactive intest ...... of G protein-coupled receptors
@nl
prefLabel
Secretin and vasoactive intest ...... of G protein-coupled receptors
@ast
Secretin and vasoactive intest ...... of G protein-coupled receptors
@en
Secretin and vasoactive intest ...... of G protein-coupled receptors
@nl
P2093
P1433
P1476
Secretin and vasoactive intest ...... of G protein-coupled receptors
@en
P2093
C D Ulrich
L J Miller
M Holtmann
P304
P356
10.1016/S0016-5085(98)70491-3
P407
P577
1998-02-01T00:00:00Z