about
Frequent downregulation and loss of WWOX gene expression in human hepatocellular carcinomaWWOX, the common chromosomal fragile site, FRA16D, cancer genePooled analysis of loss of heterozygosity in breast cancer: a genome scan provides comparative evidence for multiple tumor suppressors and identifies novel candidate regions.ATR preferentially interacts with common fragile site FRA3B and the binding requires its kinase activity in response to aphidicolin treatment.Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell linesParkin enhances the expression of cyclin-dependent kinase 6 and negatively regulates the proliferation of breast cancer cellsOne in four individuals of African-American ancestry harbors a 5.5kb deletion at chromosome 11q13.1.Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites.Are common fragile sites merely structural domains or highly organized "functional" units susceptible to oncogenic stress?SMAD5 gene expression, rearrangements, copy number, and amplification at fragile site FRA5C in human hepatocellular carcinomaParkin, a gene implicated in autosomal recessive juvenile parkinsonism, is a candidate tumor suppressor gene on chromosome 6q25-q27Admixture fine-mapping in African Americans implicates XAF1 as a possible sarcoidosis risk geneMatrix attachment region (MAR) properties and abnormal expansion of AT island minisatellites in FRA16B fragile sites in leukemic CEM cells.Expression of common chromosomal fragile site genes, WWOX/FRA16D and FHIT/FRA3B is downregulated by exposure to environmental carcinogens, UV, and BPDE but not by IR.
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Common fragile sites and cancer (review)
@ast
Common fragile sites and cancer (review)
@en
Common fragile sites and cancer (review)
@nl
type
label
Common fragile sites and cancer (review)
@ast
Common fragile sites and cancer (review)
@en
Common fragile sites and cancer (review)
@nl
prefLabel
Common fragile sites and cancer (review)
@ast
Common fragile sites and cancer (review)
@en
Common fragile sites and cancer (review)
@nl
P2093
P1476
Common fragile sites and cancer (review)
@en
P2093
P304
P407
P577
1998-01-01T00:00:00Z