Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites. - Wikidata - awgldk - TriplyDB

Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites.

Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites.

http://www.wikidata.org/entity/Q34212683

about

Inhibition of topoisomerase I prevents chromosome breakage at common fragile sites Chromothripsis from DNA damage in micronuclei.Replication stress in Mammalian cells and its consequences for mitosis Chromosome fragile sites in Arabidopsis harbor matrix attachment regions that may be associated with ancestral chromosome rearrangement events Interference in DNA replication can cause mitotic chromosomal breakage unassociated with double-strand breaks Potential biomarkers of DNA replication stress in cancer.Mechanisms of genomic instabilities underlying two common fragile-site-associated loci, PARK2 and DMD, in germ cell and cancer cell lines Condensin II initiates sister chromatid resolution during S phase.Epstein-Barr virus BGLF4 kinase retards cellular S-phase progression and induces chromosomal abnormality.Topoisomerase II- and condensin-dependent breakage of MEC1ATR-sensitive fragile sites occurs independently of spindle tension, anaphase, or cytokinesis.PUL21a-Cyclin A2 interaction is required to protect human cytomegalovirus-infected cells from the deleterious consequences of mitotic entry.Are common fragile sites merely structural domains or highly organized "functional" units susceptible to oncogenic stress?Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site.Stepwise activation of the ATR signaling pathway upon increasing replication stress impacts fragile site integrity Fragile site instability in Saccharomyces cerevisiae causes loss of heterozygosity by mitotic crossovers and break-induced replication.The Fanconi Anemia Pathway Protects Genome Integrity from R-loops.Epstein-Barr virus BGLF4 kinase induces premature chromosome condensation through activation of condensin and topoisomerase II.Genomic instability in the PARK2 locus is associated with Parkinson's disease.DNA replication timing, genome stability and cancer: late and/or delayed DNA replication timing is associated with increased genomic instability.How unfinished business from S-phase affects mitosis and beyond Chromothripsis and beyond: rapid genome evolution from complex chromosomal rearrangements Common fragile sites are characterized by histone hypoacetylation.Regulation of Replication Fork Advance and Stability by Nucleosome Assembly.Delineation of subtelomeric deletion of the long arm of chromosome 6.R Loops and Links to Human Disease.ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis.S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion.The Role of Replication-Associated Repair Factors on R-Loops Molecular profiling of common fragile sites in human fibroblasts.No significant level of inheritable interchromosomal aberrations in the progeny of bystander primary human fibroblast after alpha particle irradiation.Essential Roles of the Smc5/6 Complex in Replication through Natural Pausing Sites and Endogenous DNA Damage Tolerance.Sites of genetic instability in mitosis and cancer.Endogenous Replication Stress in Mother Cells Leads to Quiescence of Daughter Cells.FANCD2 binding identifies conserved fragile sites at large transcribed genes in avian cells.The Detection and Analysis of Chromosome Fragile Sites.

P2860

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P2860

Premature condensation induces breaks at the interface of early and late replicating chromosome bands bearing common fragile sites.

http://www.wikidata.org/entity/Q34212683

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2005 nî lūn-bûn

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2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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Proceedings of the National Academy of Sciences of the United States of America

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Premature condensation induces ...... bearing common fragile sites.

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P2093

Bernard Dutrillaux

http://www.w3.org/2001/XMLSchema#string

Eliane El Achkar

http://www.w3.org/2001/XMLSchema#string

Martine Muleris

http://www.w3.org/2001/XMLSchema#string

Michelle Debatisse

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Michelle Gerbault-Seureau

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P2860

Common chromosomal fragile site FRA16D sequence: identification of the FOR gene spanning FRA16D and homozygous deletions and translocation breakpoints in cancer cells

Chromosomal instability at common fragile sites in Seckel syndrome

Molecular basis for expression of common and rare fragile sites

Initiation of the breakage-fusion-bridge mechanism through common fragile site activation in human breast cancer cells: the model of PIP gene duplication from a break at FRA7I

Domain disruption and mutation of the bZIP transcription factor, MAF, associated with cataract, ocular anterior segment dysgenesis and coloboma

Common fragile sites and cancer (review)

DNA polymerase alpha inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes

BRCA1 is required for common-fragile-site stability via its G2/M checkpoint function

ATR Regulates Fragile Site Stability

Regulation of DNA replication by ATR: signaling in response to DNA intermediates.

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18069-18074

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16330769

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1312387

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