Carbon isotope effect study on orotidine 5'-monophosphate decarboxylase: support for an anionic intermediate

Carbon isotope effect study on orotidine 5'-monophosphate decarboxylase: support for an anionic intermediate

Item
http://www.wikidata.org/entity/Q28261150
Mechanism of the Orotidine 5′-Monophosphate Decarboxylase-Catalyzed Reaction: Evidence for Substrate Destabilization ,Structural determinants for the inhibitory ligands of orotidine-5′-monophosphate decarboxylaseMechanism of the Orotidine 5′-Monophosphate Decarboxylase-Catalyzed Reaction: Importance of Residues in the Orotate Binding SiteConformational Changes in Orotidine 5′-Monophosphate Decarboxylase: A Structure-Based Explanation for How the 5′-Phosphate Group Activates the EnzymeA Substrate-Assisted Mechanism of Nucleophile Activation in a Ser–His–Asp Containing C–C Bond HydrolaseSubstrate Distortion Contributes to the Catalysis of Orotidine 5′-Monophosphate DecarboxylaseProton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituentProduct deuterium isotope effects for orotidine 5'-monophosphate decarboxylase: effect of changing substrate and enzyme structure on the partitioning of the vinyl carbanion reaction intermediate.Determination of the amino acid sequence requirements for catalysis by the highly proficient orotidine monophosphate decarboxylase.Investigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitution.Enzyme architecture: deconstruction of the enzyme-activating phosphodianion interactions of orotidine 5'-monophosphate decarboxylase.Rate and Equilibrium Constants for an Enzyme Conformational Change during Catalysis by Orotidine 5'-Monophosphate DecarboxylaseCatalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates.Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5'-phosphate decarboxylase-catalyzed reactions.Orotic acid decarboxylation in water and nonpolar solvents: a potential role for desolvation in the action of OMP decarboxylase.An examination of the relationship between active site loop size and thermodynamic activation parameters for orotidine 5'-monophosphate decarboxylase from mesophilic and thermophilic organismsMechanism of the orotidine 5'-monophosphate decarboxylase-catalyzed reaction: effect of solvent viscosity on kinetic constants.
P2860

Carbon isotope effect study on orotidine 5'-monophosphate decarboxylase: support for an anionic intermediate

Item
http://www.wikidata.org/entity/Q28261150
description
2008 nî lūn-bûn
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2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
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2008 թվականի հունվարին հրատարակված գիտական հոդված
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2008年の論文
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年学术文章
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2008年學術文章
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name
Carbon isotope effect study on ...... rt for an anionic intermediate
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Carbon isotope effect study on ...... rt for an anionic intermediate
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Carbon isotope effect study on ...... rt for an anionic intermediate
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type
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Carbon isotope effect study on ...... rt for an anionic intermediate
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Carbon isotope effect study on ...... rt for an anionic intermediate
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Carbon isotope effect study on ...... rt for an anionic intermediate
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Carbon isotope effect study on ...... rt for an anionic intermediate
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Carbon isotope effect study on ...... rt for an anionic intermediate
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Carbon isotope effect study on ...... rt for an anionic intermediate
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P1433
P1476
P2093
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P31
P356
P407
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P1433
P1476
Carbon isotope effect study on ...... rt for an anionic intermediate
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P2093
P304
P31
P356
P407
P433
P478
P577
P5875
P698