Product deuterium isotope effects for orotidine 5'-monophosphate decarboxylase: effect of changing substrate and enzyme structure on the partitioning of the vinyl carbanion reaction intermediate.
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Conformational Changes in Orotidine 5′-Monophosphate Decarboxylase: A Structure-Based Explanation for How the 5′-Phosphate Group Activates the EnzymeAtomic Resolution Structure of the Orotidine 5'-Monophosphate Decarboxylase Product Complex Combined with Surface Plasmon Resonance Analysis: IMPLICATIONS FOR THE CATALYTIC MECHANISMSubstrate Distortion Contributes to the Catalysis of Orotidine 5′-Monophosphate DecarboxylaseProton transfer from C-6 of uridine 5'-monophosphate catalyzed by orotidine 5'-monophosphate decarboxylase: formation and stability of a vinyl carbanion intermediate and the effect of a 5-fluoro substituentEnzymatic Catalysis of Proton Transfer and Decarboxylation Reactions.Determination of the amino acid sequence requirements for catalysis by the highly proficient orotidine monophosphate decarboxylase.Investigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitution.Enzyme architecture: deconstruction of the enzyme-activating phosphodianion interactions of orotidine 5'-monophosphate decarboxylase.OMP decarboxylase: phosphodianion binding energy is used to stabilize a vinyl carbanion intermediate.Rate and Equilibrium Constants for an Enzyme Conformational Change during Catalysis by Orotidine 5'-Monophosphate DecarboxylaseSubstrate Distortion and the Catalytic Reaction Mechanism of 5-Carboxyvanillate Decarboxylase.Catalysis by orotidine 5'-monophosphate decarboxylase: effect of 5-fluoro and 4'-substituents on the decarboxylation of two-part substrates.Role of a guanidinium cation-phosphodianion pair in stabilizing the vinyl carbanion intermediate of orotidine 5'-phosphate decarboxylase-catalyzed reactions.Design of inhibitors of ODCase.Primary Deuterium Kinetic Isotope Effects From Product Yields: Rationale, Implementation, and Interpretation.Orotidine 5'-Monophosphate Decarboxylase: Probing the Limits of the Possible for Enzyme Catalysis.
P2860
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P2860
Product deuterium isotope effects for orotidine 5'-monophosphate decarboxylase: effect of changing substrate and enzyme structure on the partitioning of the vinyl carbanion reaction intermediate.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Product deuterium isotope effe ...... rbanion reaction intermediate.
@ast
Product deuterium isotope effe ...... rbanion reaction intermediate.
@en
type
label
Product deuterium isotope effe ...... rbanion reaction intermediate.
@ast
Product deuterium isotope effe ...... rbanion reaction intermediate.
@en
prefLabel
Product deuterium isotope effe ...... rbanion reaction intermediate.
@ast
Product deuterium isotope effe ...... rbanion reaction intermediate.
@en
P2093
P2860
P356
P1476
Product deuterium isotope effe ...... rbanion reaction intermediate.
@en
P2093
Bryant M Wood
John A Gerlt
Krisztina Toth
Tina L Amyes
P2860
P304
P356
10.1021/JA102408K
P407
P577
2010-05-01T00:00:00Z