Cytoplasmic gamma-actin is not required for skeletal muscle development but its absence leads to a progressive myopathy
about
Multiphasic analysis of whole exome sequencing data identifies a novel mutation of ACTG1 in a nonsyndromic hearing loss familyThe actin gene family: function follows isoformCytoskeletal tropomyosin Tm5NM1 is required for normal excitation-contraction coupling in skeletal muscleDestabilization of the dystrophin-glycoprotein complex without functional deficits in alpha-dystrobrevin null muscleOverexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotypeSmooth muscle α actin (Acta2) and myofibroblast function during hepatic wound healing.Actin in hair cells and hearing loss.Gamma-actin is required for cytoskeletal maintenance but not developmentβ-actin and γ-actin are each dispensable for auditory hair cell development but required for Stereocilia maintenance.Skeletal muscle-specific ablation of gamma(cyto)-actin does not exacerbate the mdx phenotype.Functional substitution by TAT-utrophin in dystrophin-deficient mice.Actin scaffolding by clathrin heavy chain is required for skeletal muscle sarcomere organization.Hypertrophic stimulation increases beta-actin dynamics in adult feline cardiomyocytesEvidence for somatic gene conversion and deletion in bipolar disorder, Crohn's disease, coronary artery disease, hypertension, rheumatoid arthritis, type-1 diabetes, and type-2 diabetes.Dynamin-2 mutations linked to Centronuclear Myopathy impair actin-dependent trafficking in muscle cells.TRPC1 channels are critical for hypertrophic signaling in the heart.Smooth muscle α actin is specifically required for the maintenance of lactationDelayed embryonic development and impaired cell growth and survival in Actg1 null mice.Targeted genomic capture and massively parallel sequencing to identify novel variants causing Chinese hereditary hearing loss.N-WASP is required for Amphiphysin-2/BIN1-dependent nuclear positioning and triad organization in skeletal muscle and is involved in the pathophysiology of centronuclear myopathy.Quadriceps myopathy caused by skeletal muscle-specific ablation of β(cyto)-actinAxonal regeneration and neuronal function are preserved in motor neurons lacking ß-actin in vivo.Tropomyosin-based regulation of the actin cytoskeleton in time and space.Progressive myopathy and defects in the maintenance of myotendinous junctions in mice that lack talin 1 in skeletal muscleTalin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions.A novel actin mRNA splice variant regulates ACTG1 expression.Identification of an FHL1 protein complex containing gamma-actin and non-muscle myosin IIB by analysis of protein-protein interactions.Baraitser-Winter cerebrofrontofacial syndrome: delineation of the spectrum in 42 cases.Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers.Inhibition of type I insulin-like growth factor receptor tyrosine kinase by picropodophyllin induces apoptosis and cell cycle arrest in T lymphoblastic leukemia/lymphoma.β-Actin specifically controls cell growth, migration, and the G-actin poolTransgenic overexpression of γ-cytoplasmic actin protects against eccentric contraction-induced force loss in mdx miceAbsence of Dystrophin Disrupts Skeletal Muscle Signaling: Roles of Ca2+, Reactive Oxygen Species, and Nitric Oxide in the Development of Muscular Dystrophy.Perk Ablation Ameliorates Myelination in S63del-Charcot-Marie-Tooth 1B Neuropathy.Cell biology of embryonic migration.Smooth muscle signalling pathways in health and disease.Context-dependent functional substitution of alpha-skeletal actin by gamma-cytoplasmic actin.Dystrophin is a microtubule-associated protein.Relative importance of βcyto- and γcyto-actin in primary mouse embryonic fibroblasts.Insights into the effects of disease-causing mutations in human actins.
P2860
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P2860
Cytoplasmic gamma-actin is not required for skeletal muscle development but its absence leads to a progressive myopathy
description
2006 nî lūn-bûn
@nan
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@ast
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@en
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@nl
type
label
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@ast
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@en
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@nl
prefLabel
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@ast
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@en
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@nl
P2093
P3181
P1433
P1476
Cytoplasmic gamma-actin is not ...... eads to a progressive myopathy
@en
P2093
Daniel P Fitzsimons
James M Ervasti
Jitandrakumar R Patel
Kevin J Sonnemann
Martin F Schneider
Richard L Moss
P304
P3181
P356
10.1016/J.DEVCEL.2006.07.001
P407
P577
2006-09-01T00:00:00Z