A novel putative receptor protein tyrosine kinase of the met family
about
Crystal structure of the HGF beta-chain in complex with the Sema domain of the Met receptorA family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptorRole of macrophage-stimulating protein and its receptor, RON tyrosine kinase, in ciliary motilityThe Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinaseSTK/RON receptor tyrosine kinase mediates both apoptotic and growth signals via the multifunctional docking site conserved among the HGF receptor familyRON is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSPA splicing variant of the RON transcript induces constitutive tyrosine kinase activity and an invasive phenotypeTransformation and scattering activities of the receptor tyrosine kinase RON/Stk in rodent fibroblasts and lack of regulation by the jaagsiekte sheep retrovirus receptor, Hyal2Tyro3, Axl, and Mertk receptor signaling in inflammatory bowel disease and colitis-associated cancerPathogenesis of RON receptor tyrosine kinase in cancer cells: activation mechanism, functional crosstalk, and signaling addictionRon receptor tyrosine kinase signaling as a therapeutic targetMET: a critical player in tumorigenesis and therapeutic targetCrystal Structure of the Sema-PSI Extracellular Domain of Human RON Receptor Tyrosine KinaseThe tyrosine kinase receptors Ron and Sea control "scattering" and morphogenesis of liver progenitor cells in vitro.The RON receptor tyrosine kinase in pancreatic cancer pathogenesis and its potential implications for future targeted therapiesEffects of PTCs on nonsense-mediated mRNA decay are dependent on PTC locationThe tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinase.Potential therapeutics specific to c-MET/RON receptor tyrosine kinases for molecular targeting in cancer therapy.RON and c-Met facilitate metastasis through the ERK signaling pathway in prostate cancer cellsThe RON tyrosine kinase receptor regulates vascular endothelial growth factor production in pancreatic cancer cells.Two independent signaling pathways mediate the antiapoptotic action of macrophage-stimulating protein on epithelial cellsThe envelope glycoprotein of friend spleen focus-forming virus covalently interacts with and constitutively activates a truncated form of the receptor tyrosine kinase Stk.The Ron/STK receptor tyrosine kinase is essential for peri-implantation development in the mouse.Hepatocyte growth factor/scatter factor-induced intracellular signalling.A novel RON splice variant lacking exon 2 activates the PI3K/AKT pathway via PTEN phosphorylation in colorectal carcinoma cells.Met-related receptor tyrosine kinase Ron in tumor growth and metastasis.Oncogenic mutants of RON and MET receptor tyrosine kinases cause activation of the beta-catenin pathway.Chk2*1100delC Acts in synergy with the Ron receptor tyrosine kinase to accelerate mammary tumorigenesis in mice.An unusual function of RON receptor tyrosine kinase as a transcriptional regulator in cooperation with EGFR in human cancer cells.STK receptor tyrosine kinase regulates susceptibility to infection with Listeria monocytogenes.The murine stk gene product, a transmembrane protein tyrosine kinase, is a receptor for macrophage-stimulating proteinDeletion or insertion in the first immunoglobulin-plexin-transcription (IPT) domain differentially regulates expression and tumorigenic activities of RON receptor Tyrosine Kinase.Mutation of juxtamembrane tyrosine residue 1001 suppresses loss-of-function mutations of the met receptor in epithelial cells.Isolation of Fully Human Antagonistic RON Antibodies Showing Efficient Block of Downstream Signaling and Cell Migration.Ron receptor regulates Kupffer cell-dependent cytokine production and hepatocyte survival following endotoxin exposure in miceThe monoclonal antibody Zt/f2 targeting RON receptor tyrosine kinase as potential therapeutics against tumor growth-mediated by colon cancer cells.RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma.The role of the c-Met pathway in lung cancer and the potential for targeted therapy.The Ron receptor promotes prostate tumor growth in the TRAMP mouse model.A 2-nt RNA enhancer on exon 11 promotes exon 11 inclusion of the Ron proto-oncogene.
P2860
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P2860
A novel putative receptor protein tyrosine kinase of the met family
description
1993 nî lūn-bûn
@nan
1993 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
name
A novel putative receptor protein tyrosine kinase of the met family
@ast
A novel putative receptor protein tyrosine kinase of the met family
@en
A novel putative receptor protein tyrosine kinase of the met family
@nl
type
label
A novel putative receptor protein tyrosine kinase of the met family
@ast
A novel putative receptor protein tyrosine kinase of the met family
@en
A novel putative receptor protein tyrosine kinase of the met family
@nl
prefLabel
A novel putative receptor protein tyrosine kinase of the met family
@ast
A novel putative receptor protein tyrosine kinase of the met family
@en
A novel putative receptor protein tyrosine kinase of the met family
@nl
P2093
P3181
P1433
P1476
A novel putative receptor protein tyrosine kinase of the met family
@en
P2093
M G Mattei
R Breathnach
P304
P3181
P407
P577
1993-05-01T00:00:00Z