An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion - Wikidata - awgldk - TriplyDB

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

http://www.wikidata.org/entity/Q28263483

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GPR41 and GPR43 in Obesity and Inflammation - Protective or Causative?Human and mouse monocytes display distinct signalling and cytokine profiles upon stimulation with FFAR2/FFAR3 short-chain fatty acid receptor agonists The short chain fatty acid receptor GPR43 regulates inflammatory signals in adipose tissue M2-type macrophages.The short-chain fatty acid receptor, FFA2, contributes to gestational glucose homeostasis.The metabolic fate of acetate in cancer.FFA2 Contribution to Gestational Glucose Tolerance Is Not Disrupted by Antibiotics GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.Loss of Free Fatty Acid Receptor 2 leads to impaired islet mass and beta cell survival.Host Genotype and Gut Microbiome Modulate Insulin Secretion and Diet-Induced Metabolic Phenotypes.Homology modeling of FFA2 identifies novel agonists that potentiate insulin secretion.The Pharmacology and Function of Receptors for Short-Chain Fatty Acids.SCFA Receptors in Pancreatic β Cells: Novel Diabetes Targets?Vinegar as a functional ingredient to improve postprandial glycemic control-human intervention findings and molecular mechanisms.Polymorphic Variation in FFA Receptors: Functions and Consequences.Key Questions for Translation of FFA Receptors: From Pharmacology to Medicines.FFA2 and FFA3 in Metabolic Regulation.The nutrition-gut microbiome-physiology axis and allergic diseases.HKDC1 Is a Novel Hexokinase Involved in Whole-Body Glucose Use Early life antibiotic exposure affects pancreatic islet development and metabolic regulation.Gut microbial metabolite short-chain fatty acids and obesity FFAR2-FFAR3 receptor heteromerization modulates short-chain fatty acid sensing.Gut Microbiota Dysbiosis Drives and Implies Novel Therapeutic Strategies for Diabetes Mellitus and Related Metabolic Diseases.The diet-derived short chain fatty acid propionate improves beta-cell function in humans and stimulates insulin secretion from human islets in vitro.Ligands at the Free Fatty Acid Receptors 2/3 (GPR43/GPR41).DNA methylation profiles correlated to striped bass sperm fertility.Short-chain fatty acids in control of energy metabolism.

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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

http://www.wikidata.org/entity/Q28263483

description

2015 nî lūn-bûn

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2015 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի հուլիսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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name

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

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type

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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

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prefLabel

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

@ast

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

@en

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

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Molecular Endocrinology

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An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion

@en

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Barton Wicksteed

http://www.w3.org/2001/XMLSchema#string

Brian T Layden

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Helena Mancebo

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Miles Fuller

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Raghavendra G Mirmira

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P2860

A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1

The Orphan G protein-coupled receptors GPR41 and GPR43 are activated by propionate and other short chain carboxylic acids

G-protein-coupled receptors and islet function-implications for treatment of type 2 diabetes.

Functional characterization of human receptors for short chain fatty acids and their role in polymorphonuclear cell activation

Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43

Acetate and propionate short chain fatty acids stimulate adipogenesis via GPCR43

Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2

Selective orthosteric free fatty acid receptor 2 (FFA2) agonists: identification of the structural and chemical requirements for selective activation of FFA2 versus FFA3

Maternal short-chain fatty acids are associated with metabolic parameters in mothers and newborns.

Beta-adrenergic signaling in the heart: dual coupling of the beta2-adrenergic receptor to G(s) and G(i) proteins.

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1055-1066

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10.1210/ME.2015-1007

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7

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29

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Medha Priyadarshini

Charles R. Mackay

Annette Gilchrist

Thierry Alquier

Vincent Poitout

Stephanie R Villa

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2015-06-15T00:00:00Z

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278330657

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26075576

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G protein-coupled receptor

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4484778

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