New genotype-phenotype linkages for directed evolution of functional proteins
about
Directed evolution: tailoring biocatalysts for industrial applicationsDirected evolution of a histone acetyltransferase--enhancing thermostability, whilst maintaining catalytic activity and substrate specificity.Microfluidic systems for biosensingSelection of proteins with desired properties from natural proteome libraries using mRNA display.Ribosome display for improved biotherapeutic molecules.Ribosome display and selection of human anti-cD22 scFvs derived from an acute lymphocytic leukemia patient.Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays.An efficient method to assemble linear DNA templates for in vitro screening and selection systemsBy-passing in vitro screening--next generation sequencing technologies applied to antibody display and in silico candidate selectionAdvantages of mRNA display selections over other selection techniques for investigation of protein-protein interactions.mRNA display using covalent coupling of mRNA to translated proteins.Isothermal DNA amplification using the T4 replisome: circular nicking endonuclease-dependent amplification and primase-based whole-genome amplificationPeptide aptamers: development and applications.In vitro selection of proteins with desired characteristics using mRNA-display.Highly diverse protein library based on the ubiquitous (β/α)₈ enzyme fold yields well-structured proteins through in vitro folding selection.In vitro affinity screening of protein and peptide binders by megavalent bead surface display.Evolution of enzyme catalysts caged in biomimetic gel-shell beads.A Shorter Route to Antibody Binders via Quantitative in vitro Bead-Display Screening and Consensus Analysis.Quantitative Affinity Determination by Fluorescence Anisotropy Measurements of Individual Nanoliter Droplets.Selection strategies for improved biocatalysts.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Directed evolution of anti-HER2 DARPins by SNAP display reveals stability/function trade-offs in the selection processBiomolecular engineering for nanobio/bionanotechnology.Directed Evolution of Proteins through In Vitro Protein Synthesis in Liposomes.Bioinspired genotype-phenotype linkages: mimicking cellular compartmentalization for the engineering of functional proteins.SNAP dendrimers: multivalent protein display on dendrimer-like DNA for directed evolution.Compartmentalized partnered replication for the directed evolution of genetic parts and circuits.A simple method to evaluate the biochemical compatibility of oil/surfactant mixtures for experiments in microdroplets.On-bead expression of recombinant proteins in an agarose gel matrix coated on a glass slide.Creating protein biocatalysts as tools for future industrial applications
P2860
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P2860
New genotype-phenotype linkages for directed evolution of functional proteins
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
New genotype-phenotype linkages for directed evolution of functional proteins
@ast
New genotype-phenotype linkages for directed evolution of functional proteins
@en
New genotype-phenotype linkages for directed evolution of functional proteins
@nl
type
label
New genotype-phenotype linkages for directed evolution of functional proteins
@ast
New genotype-phenotype linkages for directed evolution of functional proteins
@en
New genotype-phenotype linkages for directed evolution of functional proteins
@nl
prefLabel
New genotype-phenotype linkages for directed evolution of functional proteins
@ast
New genotype-phenotype linkages for directed evolution of functional proteins
@en
New genotype-phenotype linkages for directed evolution of functional proteins
@nl
P2093
P3181
P1476
New genotype-phenotype linkages for directed evolution of functional proteins
@en
P2093
Andrew D Griffiths
Florian Hollfelder
Viktor Stein
P3181
P356
10.1016/J.SBI.2005.07.006
P407
P577
2005-08-01T00:00:00Z