By-passing in vitro screening--next generation sequencing technologies applied to antibody display and in silico candidate selection
about
Exploring the Secretomes of Microbes and Microbial Communities Using Filamentous Phage DisplayDeep sequencing in library selection projects: what insight does it bring?Opportunities for functional selectivity in GPCR antibodiesPHASTpep: Analysis Software for Discovery of Cell-Selective Peptides via Phage Display and Next-Generation Sequencing.In-cell intrabody selection from a diverse human library identifies C12orf4 protein as a new player in rodent mast cell degranulationAcousto-microfluidics for screening of ssDNA aptamer.Sequencing antibody repertoires: the next generation.The functional repertoire of rabbit antibodies and antibody discovery via next-generation sequencing.IG and TR single chain fragment variable (scFv) sequence analysis: a new advanced functionality of IMGT/V-QUEST and IMGT/HighV-QUEST.The promise and challenge of high-throughput sequencing of the antibody repertoire.Phenotype-information-phenotype cycle for deconvolution of combinatorial antibody libraries selected against complex systems.Enrich: software for analysis of protein function by enrichment and depletion of variants.Comprehensive assessment of potential multiple myeloma immunoglobulin heavy chain V-D-J intraclonal variation using massively parallel pyrosequencing.From deep sequencing to actual clonesDeep Panning: steps towards probing the IgOme.Synthetic customized scFv libraries.Transferring the characteristics of naturally occurring and biased antibody repertoires to human antibody libraries by trapping CDRH3 sequencesAntibody isolation from immunized animals: comparison of phage display and antibody discovery via V gene repertoire mining.Construction of a rationally designed antibody platform for sequencing-assisted selection.Next-generation antibody discovery platforms.Single-round, multiplexed antibody mimetic design through mRNA display.Using phage and yeast display to select hundreds of monoclonal antibodies: application to antigen 85, a tuberculosis biomarker.A fully synthetic human Fab antibody library based on fixed VH/VL framework pairings with favorable biophysical properties.Identification of target-binding peptide motifs by high-throughput sequencing of phage-selected peptides.Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing.The application of next generation sequencing to the understanding of antibody repertoires.Deep sequencing and Circos analyses of antibody libraries reveal antigen-driven selection of Ig VH genes during HIV-1 infectionProspective identification of parasitic sequences in phage display screens.Preparing unbiased T-cell receptor and antibody cDNA libraries for the deep next generation sequencing profiling.Exploiting light chains for the scalable generation and platform purification of native human bispecific IgG.FASTAptamer: A Bioinformatic Toolkit for High-throughput Sequence Analysis of Combinatorial Selections.Deep mutational scanning: assessing protein function on a massive scale.Principles and application of antibody libraries for infectious diseases.Library construction, selection and modification strategies to generate therapeutic peptide-based modulators of protein-protein interactions.Progress in the development of immunoanalytical methods incorporating recombinant antibodies to small molecular weight biotoxins.Effective Optimization of Antibody Affinity by Phage Display Integrated with High-Throughput DNA Synthesis and Sequencing TechnologiesConceptual and methodological advances in cell-free directed evolution.High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum.High-Throughput Ligand Discovery Reveals a Sitewise Gradient of Diversity in Broadly Evolved Hydrophilic Fibronectin DomainsDefining the complementarities between antibodies and haptens to refine our understanding and aid the prediction of a successful binding interaction.
P2860
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P2860
By-passing in vitro screening--next generation sequencing technologies applied to antibody display and in silico candidate selection
description
2010 nî lūn-bûn
@nan
2010 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
By-passing in vitro screening- ...... in silico candidate selection
@ast
By-passing in vitro screening- ...... in silico candidate selection
@en
type
label
By-passing in vitro screening- ...... in silico candidate selection
@ast
By-passing in vitro screening- ...... in silico candidate selection
@en
prefLabel
By-passing in vitro screening- ...... in silico candidate selection
@ast
By-passing in vitro screening- ...... in silico candidate selection
@en
P2093
P2860
P356
P1476
By-passing in vitro screening- ...... in silico candidate selection
@en
P2093
G Magistrelli
L Baerlocher
L Farinelli
M H Kosco-Vilbois
P2860
P356
10.1093/NAR/GKQ789
P407
P577
2010-09-15T00:00:00Z