Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis - Wikidata - awgldk - TriplyDB

Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis

Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis

http://www.wikidata.org/entity/Q28264081

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L-plastin nanobodies perturb matrix degradation, podosome formation, stability and lifetime in THP-1 macrophages The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function Dynamics of podosome stiffness revealed by atomic force microscopy HIV-1 Infection of T Lymphocytes and Macrophages Affects Their Migration via Nef Connexins, gap junctions and tissue invasion Multiparametric classification links tumor microenvironments with tumor cell phenotype The F-BAR protein PSTPIP1 controls extracellular matrix degradation and filopodia formation in macrophages.Single-domain antibody-SH3 fusions for efficient neutralization of HIV-1 Nef functions Macrophage mesenchymal migration requires podosome stabilization by filamin A Frustrated phagocytosis on micro-patterned immune complexes to characterize lysosome movements in live macrophages Hck contributes to bone homeostasis by controlling the recruitment of osteoclast precursors.The process of macrophage migration promotes matrix metalloproteinase-independent invasion by tumor cells.Tyrosine phosphorylation of WIP releases bound WASP and impairs podosome assembly in macrophages Imaging podosome dynamics and matrix degradation Podosomes in adhesion, migration, mechanosensing and matrix remodeling.The podosome marker protein Tks5 regulates macrophage invasive behavior.Progesterone and Src family inhibitor PP1 synergistically inhibit cell migration and invasion of human basal phenotype breast cancer cells MT1-MMP regulates the PI3Kδ·Mi-2/NuRD-dependent control of macrophage immune function.Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility.The Src-Family Kinases Hck and Fgr Regulate Early Lipopolysaccharide-Induced Myeloid Cell Recruitment into the Lung and Their Ability To Secrete Chemokines.Hematopoietic cell kinase (HCK) as a therapeutic target in immune and cancer cells.Tuberculosis is associated with expansion of a motile, permissive and immunomodulatory CD16(+) monocyte population via the IL-10/STAT3 axis.Recombinant protein rVP1 upregulates BECN1-independent autophagy, MAPK1/3 phosphorylation and MMP9 activity via WIPI1/WIPI2 to promote macrophage migration.Α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction.Cell motility is decreased in macrophages activated by cancer cell-conditioned medium.Tyrosine phosphorylation of Wiskott-Aldrich syndrome protein (WASP) by Hck regulates macrophage function.Signaling networks regulating leukocyte podosome dynamics and function.Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis.Podosomes in space: macrophage migration and matrix degradation in 2D and 3D settings.Tools of the trade: podosomes as multipurpose organelles of monocytic cells.Control of macrophage 3D migration: a therapeutic challenge to limit tissue infiltration.Human Macrophages Utilize the Podosome Formin FMNL1 for Adhesion and Migration.Trim33 is essential for macrophage and neutrophil mobilization to developmental or inflammatory cues.Dynamic interactions of neutrophils and biofilms.RABGTPases in MT1-MMP trafficking and cell invasion: Physiology versus pathology.Podosomes in migrating microglia: components and matrix degradation.Nanomechanical measurement of adhesion and migration of leukemia cells with phorbol 12-myristate 13-acetate treatment Src family kinase expression and subcellular localization in macrophages: implications for their role in CSF-1-induced macrophage migration.S100A4 regulates macrophage invasion by distinct myosin-dependent and myosin-independent mechanisms.An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages.

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Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis

http://www.wikidata.org/entity/Q28264081

description

2010 nî lūn-bûn

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2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2010 թվականի փետրվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年学术文章

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2010年學術文章

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Three-dimensional migration of ...... tracellular matrix proteolysis

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Three-dimensional migration of ...... tracellular matrix proteolysis

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Clifford A Lowell

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Jean-Louis Mège

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Nathalie Laviolette-Malirat

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P2860

p59Hck isoform induces F-actin reorganization to form protrusions of the plasma membrane in a Cdc42- and Rac-dependent manner

Activation of the lysosome-associated p61Hck isoform triggers the biogenesis of podosomes

Hematopoietic cell kinase (Hck) isoforms and phagocyte duties - from signaling and actin reorganization to migration and phagocytosis

Cancer-related inflammation

Invadopodia: specialized cell structures for cancer invasion

Assembly and biological role of podosomes and invadopodia

The matrix corroded: podosomes and invadopodia in extracellular matrix degradation

Persistent Coxiella burnetii infection in mice overexpressing IL-10: an efficient model for chronic Q fever pathogenesis

Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity

Macrophages: Obligate Partners for Tumor Cell Migration, Invasion, and Metastasis

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1444-52

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10.1182/BLOOD-2009-04-218735

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Céline Cougoule

Isabelle Maridonneau-Parini

Véronique Le Cabec

Renaud Poincloux

Guillaume Tabouret

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2010-02-18T00:00:00Z

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38074807

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19897576

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