Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity
about
The tyrosine kinase Hck is an inhibitor of HIV-1 replication counteracted by the viral vif proteinIdentification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolaeSeparable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signalingFgr but not Syk tyrosine kinase is a target for beta 2 integrin-induced c-Cbl-mediated ubiquitination in adherent human neutrophilsCapturing genes encoding membrane and secreted proteins important for mouse developmentParallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxisIdentification of tyrosine residues on ELMO1 that are phosphorylated by the Src-family kinase Hck.Intersecting roles of protein tyrosine kinase and calcium signaling during fertilizationSequential assignment and secondary structure determination for the Src homology 2 domain of hematopoietic cellular kinaseBiochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with HckThree-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysisThe Escherichia coli phosphotyrosine proteome relates to core pathways and virulencePhosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinaseHIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction.The Src family kinase Hck couples BCR/ABL to STAT5 activation in myeloid leukemia cells.The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.Sequential requirements of the N-terminal palmitoylation site and SH2 domain of Src family kinases in the initiation and progression of FcepsilonRI signaling.Phosphorylation of Enabled by the Drosophila Abelson tyrosine kinase regulates the in vivo function and protein-protein interactions of EnabledBinding of src-like kinases to the beta-subunit of the interleukin-3 receptor.Regulation of the Src protein tyrosine kinase.A novel nonreceptor tyrosine kinase, Srm: cloning and targeted disruption.PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.Hck contributes to bone homeostasis by controlling the recruitment of osteoclast precursors.Splenic Dendritic Cells Survey Red Blood Cells for Missing Self-CD47 to Trigger Adaptive Immune Responses.Requirement for nuclear factor kappa B signalling in the interleukin-1-induced expression of the CCAAT/enhancer binding protein-delta gene in hepatocytes.Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer ProgressionA general strategy for producing conditional alleles of Src-like tyrosine kinases.Src and Ras are involved in separate pathways in epithelial cell scattering.Genetic interactions between the Drosophila Abelson (Abl) tyrosine kinase and failed axon connections (fax), a novel protein in axon bundles.C-Src and c-Yes are two unlikely partners of spermatogenesis and their roles in blood-testis barrier dynamics.Determinants of the phagocytic signal mediated by the type IIIA Fc gamma receptor, Fc gamma RIIIA: sequence requirements and interaction with protein-tyrosine kinases.Krüppel-like factor 4 regulates macrophage polarization.The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitmentDistinct and overlapping functional roles of Src family kinases in mouse platelets.ROS-triggered phosphorylation of complex II by Fgr kinase regulates cellular adaptation to fuel useSrc family kinases mediate neutrophil adhesion to adherent platelets.Global H3K4me3 genome mapping reveals alterations of innate immunity signaling and overexpression of JMJD3 in human myelodysplastic syndrome CD34+ cells.Src family kinases are important negative regulators of G-CSF-dependent granulopoiesisThe Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn
P2860
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P2860
Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity
description
1994 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1994
@ast
im Februar 1994 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1994/02/15)
@sk
vědecký článek publikovaný v roce 1994
@cs
wetenschappelijk artikel (gepubliceerd op 1994/02/15)
@nl
наукова стаття, опублікована в лютому 1994
@uk
научни чланак (објављен 1994/02/15)
@sr
name
Functional overlap in the src ...... d fgr impairs natural immunity
@ast
Functional overlap in the src ...... d fgr impairs natural immunity
@en
Functional overlap in the src ...... d fgr impairs natural immunity
@nl
type
label
Functional overlap in the src ...... d fgr impairs natural immunity
@ast
Functional overlap in the src ...... d fgr impairs natural immunity
@en
Functional overlap in the src ...... d fgr impairs natural immunity
@nl
prefLabel
Functional overlap in the src ...... d fgr impairs natural immunity
@ast
Functional overlap in the src ...... d fgr impairs natural immunity
@en
Functional overlap in the src ...... d fgr impairs natural immunity
@nl
P3181
P356
P1433
P1476
Functional overlap in the src ...... d fgr impairs natural immunity
@en
P2093
C. A. Lowell
P. Soriano
P304
P3181
P356
10.1101/GAD.8.4.387
P577
1994-02-15T00:00:00Z