Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity
about
Emerging drugs of abuse: current perspectives on synthetic cannabinoidsContributions of academic laboratories to the discovery and development of chemical biology toolsDistinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ(9)-THC: mechanism underlying greater toxicity?Synthesis and preliminary evaluation of [18F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB2 receptorDetection of urinary metabolites of AM-2201 and UR-144, two novel synthetic cannabinoids.The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse.Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids.Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.UR-144 in products sold via the Internet: identification of related compounds and characterization of pyrolysis products.Δ9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market.First metabolic profile of XLR-11, a novel synthetic cannabinoid, obtained by using human hepatocytes and high-resolution mass spectrometryDevelopment and preliminary validation of a plate-based CB1/CB2 receptor functional assayCannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles.Optimization of novel indole-2-carboxamide inhibitors of neurotropic alphavirus replication.Current and emerging "at-site" pain medications: a reviewPrediction of designer drugs: synthesis and spectroscopic analysis of synthetic cannabinoid analogues of 1H-indol-3-yl(2,2,3,3-tetramethylcyclopropyl)methanone and 1H-indol-3-yl(adamantan-1-yl)methanone.Combination Chemistry: Structure-Activity Relationships of Novel Psychoactive Cannabinoids.Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites.3D-QSAR/CoMFA-based structure-affinity/selectivity relationships of aminoalkylindoles in the cannabinoid CB1 and CB2 receptors.The Influence of Synthetic Cannabinoid UR-144 on Human Psychomotor Performance--A Case Report Demonstrating Road Traffic Risks.Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro AssaysAnalysis of Parent Synthetic Cannabinoids in Blood and Urinary Metabolites by Liquid Chromatography Tandem Mass Spectrometry.Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids.Synthetic cannabinoid use associated with acute kidney injury.Lateral flow immunoassay and enzyme linked immunosorbent assay as effective immunomethods for the detection of synthetic cannabinoid JWH-200 based on the newly synthesized hapten.Disruption of hippocampal synaptic transmission and long-term potentiation by psychoactive synthetic cannabinoid 'Spice' compounds: comparison with Δ9 -tetrahydrocannabinol.Determination of urinary metabolites of XLR-11 by liquid chromatography-quadrupole time-of-flight mass spectrometry.Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonistChemical analysis of a benzofuran derivative, 2-(2-ethylaminopropyl)benzofuran (2-EAPB), eight synthetic cannabinoids, five cathinone derivatives, and five other designer drugs newly detected in illegal productsCytochrome P450-mediated metabolism of the synthetic cannabinoids UR-144 and XLR-11Structure–activity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologuesIdentification and structural characterization of the synthetic cannabinoid 3-(1-adamantoyl)-1-pentylindole as an additive in ‘herbal incense’
P2860
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P2860
Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@ast
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@en
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@nl
type
label
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@ast
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@en
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@nl
prefLabel
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@ast
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@en
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@nl
P2093
P921
P3181
P356
P1476
Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity
@en
P2093
Anthony V Daza
Betty B Yao
Chang Z Zhu
George K Grayson
Gin C Hsieh
Jennifer M Frost
Karin R Tietje
Madhavi Pai
Michael D Meyer
Michael J Dart
P304
P3181
P356
10.1021/JM901214Q
P407
P577
2010-01-14T00:00:00Z