Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity - Wikidata - awgldk - TriplyDB

Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity

Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity

http://www.wikidata.org/entity/Q28265080

about

Emerging drugs of abuse: current perspectives on synthetic cannabinoids Contributions of academic laboratories to the discovery and development of chemical biology tools Distinct pharmacology and metabolism of K2 synthetic cannabinoids compared to Δ(9)-THC: mechanism underlying greater toxicity?Synthesis and preliminary evaluation of [18F]-labeled 2-oxoquinoline derivatives for PET imaging of cannabinoid CB2 receptor Detection of urinary metabolites of AM-2201 and UR-144, two novel synthetic cannabinoids.The synthesis and pharmacological evaluation of adamantane-derived indoles: cannabimimetic drugs of abuse.Moving around the molecule: relationship between chemical structure and in vivo activity of synthetic cannabinoids.Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.UR-144 in products sold via the Internet: identification of related compounds and characterization of pyrolysis products.Δ9-Tetrahydrocannabinol-like effects of novel synthetic cannabinoids found on the gray market.First metabolic profile of XLR-11, a novel synthetic cannabinoid, obtained by using human hepatocytes and high-resolution mass spectrometry Development and preliminary validation of a plate-based CB1/CB2 receptor functional assay Cannabinoids in disguise: Δ9-tetrahydrocannabinol-like effects of tetramethylcyclopropyl ketone indoles.Optimization of novel indole-2-carboxamide inhibitors of neurotropic alphavirus replication.Current and emerging "at-site" pain medications: a review Prediction of designer drugs: synthesis and spectroscopic analysis of synthetic cannabinoid analogues of 1H-indol-3-yl(2,2,3,3-tetramethylcyclopropyl)methanone and 1H-indol-3-yl(adamantan-1-yl)methanone.Combination Chemistry: Structure-Activity Relationships of Novel Psychoactive Cannabinoids.Pharmacological and Toxicological Effects of Synthetic Cannabinoids and Their Metabolites.3D-QSAR/CoMFA-based structure-affinity/selectivity relationships of aminoalkylindoles in the cannabinoid CB1 and CB2 receptors.The Influence of Synthetic Cannabinoid UR-144 on Human Psychomotor Performance--A Case Report Demonstrating Road Traffic Risks.Stratification of Cannabinoid 1 Receptor (CB1R) Agonist Efficacy: Manipulation of CB1R Density through Use of Transgenic Mice Reveals Congruence between In Vivo and In Vitro Assays Analysis of Parent Synthetic Cannabinoids in Blood and Urinary Metabolites by Liquid Chromatography Tandem Mass Spectrometry.Discriminative Stimulus Properties of Phytocannabinoids, Endocannabinoids, and Synthetic Cannabinoids.Synthetic cannabinoid use associated with acute kidney injury.Lateral flow immunoassay and enzyme linked immunosorbent assay as effective immunomethods for the detection of synthetic cannabinoid JWH-200 based on the newly synthesized hapten.Disruption of hippocampal synaptic transmission and long-term potentiation by psychoactive synthetic cannabinoid 'Spice' compounds: comparison with Δ9 -tetrahydrocannabinol.Determination of urinary metabolites of XLR-11 by liquid chromatography-quadrupole time-of-flight mass spectrometry.Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist Chemical analysis of a benzofuran derivative, 2-(2-ethylaminopropyl)benzofuran (2-EAPB), eight synthetic cannabinoids, five cathinone derivatives, and five other designer drugs newly detected in illegal products Cytochrome P450-mediated metabolism of the synthetic cannabinoids UR-144 and XLR-11 Structure–activity relationships of synthetic cannabinoid designer drug RCS-4 and its regioisomers and C4 homologues Identification and structural characterization of the synthetic cannabinoid 3-(1-adamantoyl)-1-pentylindole as an additive in ‘herbal incense’

P2860

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P2860

Indol-3-ylcycloalkyl ketones: effects of N1 substituted indole side chain variations on CB(2) cannabinoid receptor activity

http://www.wikidata.org/entity/Q28265080

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity

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Indol-3-ylcycloalkyl ketones: ...... cannabinoid receptor activity

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Anthony V Daza

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Betty B Yao

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Chang Z Zhu

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George K Grayson

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