Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist
about
A synthetic cannabinoid FDU-NNEI, two 2H-indazole isomers of synthetic cannabinoids AB-CHMINACA and NNEI indazole analog (MN-18), a phenethylamine derivative N–OH-EDMA, and a cathinone derivative dimethoxy-α-PHP, newly identified in illegal productsMotor vehicle collisions caused by the 'super-strength' synthetic cannabinoids, MAM-2201, 5F-PB-22, 5F-AB-PINACA, 5F-AMB and 5F-ADB in Japan experienced from 2012 to 2014.An Expanding World of Novel Psychoactive Substances: Opioids.Recreational drug discovery: natural products as lead structures for the synthesis of smart drugs.UPLC/ESI-MS/MS-based determination of metabolism of several new illicit drugs, ADB-FUBINACA, AB-FUBINACA, AB-PINACA, QUPIC, 5F-QUPIC and α-PVT, by human liver microsome.'Crazy Monkey' poisons man and dog: Human and canine seizures due to PB-22, a novel synthetic cannabinoid.Identification and analytical characteristics of synthetic cannabinoids with an indazole-3-carboxamide structure bearing a N-1-methoxycarbonylalkyl group.In vitro, in vivo and in silico metabolic profiling of α-pyrrolidinopentiothiophenone, a novel thiophene stimulant.Death Associated With the Use of the Synthetic Cannabinoid ADB-FUBINACA.Four types of cannabimimetic indazole and indole derivatives, ADB-BINACA, AB-FUBICA, ADB-FUBICA, and AB-BICA, identified as new psychoactive substances.Cytotoxic Activity of Pyrovalerone Derivatives, an Emerging Group of Psychostimulant Designer Cathinones.Pharmacological evaluation of synthetic cannabinoids identified as constituents of spice.Near death from a novel synthetic opioid labeled U-47700: emergence of a new opioid class.Novel psychoactive substances of interest for psychiatry.AH-7921: the list of new psychoactive opioids is expanded.Comprehensive review of the detection methods for synthetic cannabinoids and cathinones.Analytical differentiation of quinolinyl- and isoquinolinyl-substituted 1-(5-fluoropentyl)-1H-indole-3-carboxylates: 5F-PB-22 and its ten isomers.Psyclones: a roller coaster of life? Hidden synthetic cannabinoids and stimulants in apparently harmless products.Synthetic cannabinoid "Black Mamba" infidelity in patients presenting for emergency stabilization in Colorado: a P SCAN Cohort.Metabolic characterization of AH-7921, a synthetic opioid designer drug: in vitro metabolic stability assessment and metabolite identification, evaluation of in silico prediction, and in vivo confirmation.A Fast and Comprehensive Analysis of 32 Synthetic Cannabinoids Using Agilent Triple Quadrupole LC-MS-MS.Phase I metabolism of the highly potent synthetic cannabinoid MDMB-CHMICA and detection in human urine samples.Identification and analytical characterization of four synthetic cannabinoids ADB-BICA, NNL-1, NNL-2, and PPA(N)-2201.Analysis of Parent Synthetic Cannabinoids in Blood and Urinary Metabolites by Liquid Chromatography Tandem Mass Spectrometry.Legal controls on cannabimimetics: an international dilemma?Fatal intoxications associated with the designer opioid AH-7921.Metabolism of synthetic cannabinoids PB-22 and its 5-fluoro analog, 5F-PB-22, by human hepatocyte incubation and high-resolution mass spectrometry.Study on the phase I metabolism of novel synthetic cannabinoids, APICA and its fluorinated analogue.Behavioral evidence for the abuse potential of the novel synthetic cathinone alpha-pyrrolidinopentiothiophenone (PVT) in rodents.Supraventricular tachycardia and acute confusion following ingestion of e-cigarette fluid containing AB-FUBINACA and ADB-FUBINACA: a case report with quantitative analysis of serum drug concentrations.Δ(9)-Tetrahydrocannabinol-like discriminative stimulus effects of five novel synthetic cannabinoids in rats.Synthetic cannabimimetic agents metabolized by carboxylesterases.Metabolic characterization of (1-(5-fluoropentyl)-1H-indol-3-yl)(4-methyl-1-naphthalenyl)-methanone (MAM-2201) using human liver microsomes and cDNA-overexpressed cytochrome P450 enzymes.Quantification of synthetic cannabinoids in herbal smoking blends using NMR.Identification of three cannabimimetic indazole and pyrazole derivatives, APINACA 2H-indazole analogue, AMPPPCA, and 5F-AMPPPCA.The synthesis and characterization of the 'research chemical' N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-3-(4-fluorophenyl)-1H-pyrazole-5-carboxamide (3,5-AB-CHMFUPPYCA) and differentiation from its 5,3-regioisomer.Changes in the prevalence of new psychoactive substances before and after the introduction of the generic scheduling of synthetic cannabinoids in Japan.Detection of synthetic cannabinoids using GC-EI-MS, positive GC-CI-MS, and negative GC-CI-MS.A fatality involving AH-7921.Identification of N,N-bis(1-pentylindol-3-yl-carboxy)naphthylamine (BiPICANA) found in an herbal blend product in the Tokyo metropolitan area and its cannabimimetic effects evaluated by in vitro [35S]GTPγS binding assays
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Two new-type cannabimimetic quinolinyl carboxylates, QUPIC and QUCHIC, two new cannabimimetic carboxamide derivatives, ADB-FUBINACA and ADBICA, and five synthetic cannabinoids detected with a thiophene derivative α-PVT and an opioid receptor agonist
description
wetenschappelijk artikel
@nl
наукова стаття, опублікована в березні 2013
@uk
name
Two new-type cannabimimetic qu ...... and an opioid receptor agonist
@en
Two new-type cannabimimetic qu ...... and an opioid receptor agonist
@nl
type
label
Two new-type cannabimimetic qu ...... and an opioid receptor agonist
@en
Two new-type cannabimimetic qu ...... and an opioid receptor agonist
@nl
prefLabel
Two new-type cannabimimetic qu ...... and an opioid receptor agonist
@en
Two new-type cannabimimetic qu ...... and an opioid receptor agonist
@nl
P2093
P2860
P921
P1433
P1476
Two new-type cannabimimetic qu ...... and an opioid receptor agonist
@en
P2093
Maiko Kawamura
Nahoko Uchiyama
Ruri Kikura-Hanajiri
Satoru Matsuda
Yukihiro Goda
P2860
P2888
P304
P356
10.1007/S11419-013-0182-9
P577
2013-03-15T00:00:00Z
P5875
P6179
1037695429