Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome
about
ELMO1 and Dock180, a bipartite Rac1 guanine nucleotide exchange factor, promote human glioma cell invasion.Glycogen synthase kinase-3 inhibition induces glioma cell death through c-MYC, nuclear factor-kappaB, and glucose regulationThe TWEAK receptor Fn14 is a potential cell surface portal for targeted delivery of glioblastoma therapeuticsThe TWEAK-Fn14 pathway: a potent regulator of skeletal muscle biology in health and diseaseA Bioinformatics Resource for TWEAK-Fn14 Signaling PathwayBAFF, APRIL, TWEAK, BCMA, TACI and Fn14 proteins are related to human glioma tumor grade: immunohistochemistry and public microarray data meta-analysis.TNF-like weak inducer of apoptosis (TWEAK) promotes beta cell neogenesis from pancreatic ductal epithelium in adult mice.Small G protein Rac GTPases regulate the maintenance of glioblastoma stem-like cells in vitro and in vivo.Regulation of fibroblast growth factor-inducible 14 (Fn14) expression levels via ligand-independent lysosomal degradationmiRNA expression profiling in migrating glioblastoma cells: regulation of cell migration and invasion by miR-23b via targeting of Pyk2.Predictive gene signature of response to the anti-TweakR mAb PDL192 in patient-derived breast cancer xenograftsTargeting Src family kinases inhibits bevacizumab-induced glioma cell invasionTWEAK-independent Fn14 self-association and NF-κB activation is mediated by the C-terminal region of the Fn14 cytoplasmic domainDevelopment of human serine protease-based therapeutics targeting Fn14 and identification of Fn14 as a new target overexpressed in TNBC.Minimizing the non-specific binding of nanoparticles to the brain enables active targeting of Fn14-positive glioblastoma cells.Reciprocal activation of transcription factors underlies the dichotomy between proliferation and invasion of glioma cells.TROY (TNFRSF19) is overexpressed in advanced glial tumors and promotes glioblastoma cell invasion via Pyk2-Rac1 signaling.Expression of Rac-1 related to tumor depth, lymph node metastasis and patient prognosis in esophageal squamous cell carcinoma.Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosisFn14•TRAIL effectively inhibits hepatocellular carcinoma growth.Chronic activation of FXR in transgenic mice caused perinatal toxicity and sensitized mice to cholesterol toxicity.Development of an Fn14 agonistic antibody as an anti-tumor agent.AR-regulated TWEAK-FN14 pathway promotes prostate cancer bone metastasisThe TWEAK-Fn14 system: breaking the silence of cytokine-induced skeletal muscle wasting.Fn14 receptor promotes invasive potential and metastatic capacity of non-small lung adenocarcinoma cells through the up-regulation of integrin α6Rap1 GTPase Inhibits Tumor Necrosis Factor-α-Induced Choroidal Endothelial Migration via NADPH Oxidase- and NF-κB-Dependent Activation of Rac1.Numbl inhibits glioma cell migration and invasion by suppressing TRAF5-mediated NF-κB activationTherapeutic potential of the TWEAK/Fn14 pathway in intractable gastrointestinal cancer.Identification of aurintricarboxylic acid as a selective inhibitor of the TWEAK-Fn14 signaling pathway in glioblastoma cellsInhibition of the TWEAK/Fn14 pathway attenuates renal disease in nephrotoxic serum nephritisCdc42 and the guanine nucleotide exchange factors Ect2 and trio mediate Fn14-induced migration and invasion of glioblastoma cellsThe fibroblast growth factor-inducible 14 receptor is highly expressed in HER2-positive breast tumors and regulates breast cancer cell invasive capacityDevelopment and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells.The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatmentThe HER2- and heregulin β1 (HRG)-inducible TNFR superfamily member Fn14 promotes HRG-driven breast cancer cell migration, invasion, and MMP9 expression.Diffuse glioma growth: a guerilla warThe Src homology 3 domain-containing guanine nucleotide exchange factor is overexpressed in high-grade gliomas and promotes tumor necrosis factor-like weak inducer of apoptosis-fibroblast growth factor-inducible 14-induced cell migration and invasioNeural stem cells, inflammation and NF-kappaB: basic principle of maintenance and repair or origin of brain tumours?The guanine nucleotide exchange factors trio, Ect2, and Vav3 mediate the invasive behavior of glioblastoma.TROY (TNFRSF19) promotes glioblastoma survival signaling and therapeutic resistance.
P2860
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P2860
Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Increased fibroblast growth fa ...... late with poor patient outcome
@ast
Increased fibroblast growth fa ...... late with poor patient outcome
@en
Increased fibroblast growth fa ...... late with poor patient outcome
@nl
type
label
Increased fibroblast growth fa ...... late with poor patient outcome
@ast
Increased fibroblast growth fa ...... late with poor patient outcome
@en
Increased fibroblast growth fa ...... late with poor patient outcome
@nl
prefLabel
Increased fibroblast growth fa ...... late with poor patient outcome
@ast
Increased fibroblast growth fa ...... late with poor patient outcome
@en
Increased fibroblast growth fa ...... late with poor patient outcome
@nl
P2093
P3181
P1433
P1476
Increased fibroblast growth fa ...... late with poor patient outcome
@en
P2093
Benjamin A Savitch
Christopher A Lipinski
Galen Hostetter
Heather E Cunliffe
Jeffrey A Winkles
Jennifer S Michaelson
Jessica L Rennert
Joseph C Loftus
Linda C Burkly
Luigi Mariani
P304
P3181
P356
10.1158/0008-5472.CAN-06-0418
P407
P577
2006-10-01T00:00:00Z