Age and sex effects on human mutation rates: an old problem with new complexities
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Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspringThe ups and downs of mutation frequencies during aging can account for the Apert syndrome paternal age effectStatement on guidance for genetic counseling in advanced paternal ageRates and fitness consequences of new mutations in humansSYNGAP1: Mind the GapSelfish spermatogonial selection: evidence from an immunohistochemical screen in testes of elderly menPaternal age effect mutations and selfish spermatogonial selection: causes and consequences for human diseaseMutation and Human Exceptionalism: Our Future Genetic LoadPositive selection for new disease mutations in the human germline: evidence from the heritable cancer syndrome multiple endocrine neoplasia type 2BHuman Germline Mutation and the Erratic Evolutionary ClockA direct characterization of human mutation based on microsatellitesThe effects of breeding protocol in C57BL/6J mice on adult offspring behaviourThe molecular anatomy of spontaneous germline mutations in human testes.Evolution of female preference for younger malesActivating mutations in FGFR3 and HRAS reveal a shared genetic origin for congenital disorders and testicular tumorsPattern of mutation rates in the germline of Drosophila melanogaster males from a large-scale mutation screening experiment.Advanced parental age and the risk of autism spectrum disorderSex: differences in mutation, recombination, selection, gene flow, and genetic drift.The effect of paternal age on offspring intelligence and personality when controlling for paternal trait levelHighly variable recessive lethal or nearly lethal mutation rates during germ-line development of male Drosophila melanogasterIncreased human AP endonuclease 1 level confers protection against the paternal age effect in mice.Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice.De novo mutations in neurological and psychiatric disorders: effects, diagnosis and prevention.A germ-line-selective advantage rather than an increased mutation rate can explain some unexpectedly common human disease mutations.Understanding what determines the frequency and pattern of human germline mutations.Advanced paternal age effects in neurodevelopmental disorders-review of potential underlying mechanisms.Measurements of spontaneous rates of mutations in the recent past and the near future.Ageing of the male germ line.Cellular evidence for selfish spermatogonial selection in aged human testes.Descriptive epidemiology of birth defects thought to arise by new mutation.Relative mutation rates of each nucleotide for another estimated from allele frequency spectra at human gene loci.The effect of parental age on NF1 patients in Turkey.Advancing paternal age and simplex autism.
P2860
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P2860
Age and sex effects on human mutation rates: an old problem with new complexities
description
2006 nî lūn-bûn
@nan
2006 թուականին հրատարակուած գիտական յօդուած
@hyw
2006 թվականին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Age and sex effects on human mutation rates: an old problem with new complexities
@ast
Age and sex effects on human mutation rates: an old problem with new complexities
@en
Age and sex effects on human mutation rates: an old problem with new complexities
@nl
type
label
Age and sex effects on human mutation rates: an old problem with new complexities
@ast
Age and sex effects on human mutation rates: an old problem with new complexities
@en
Age and sex effects on human mutation rates: an old problem with new complexities
@nl
altLabel
Age and Sex Effects on Human Mutation Rates: An Old Problem with New Complexities
@ast
Age and Sex Effects on Human Mutation Rates: An Old Problem with New Complexities
@en
prefLabel
Age and sex effects on human mutation rates: an old problem with new complexities
@ast
Age and sex effects on human mutation rates: an old problem with new complexities
@en
Age and sex effects on human mutation rates: an old problem with new complexities
@nl
P2860
P3181
P356
P1476
Age and Sex Effects on Human Mutation Rates: An Old Problem with New Complexities
@en
Age and sex effects on human mutation rates: an old problem with new complexities
@en
P2093
James F Crow
James F. CROW
P2860
P3181
P356
10.1269/JRR.47.B75
P407
P433
SupplementB
P577
2006-01-01T00:00:00Z