Dendritic Spine Instability in a Mouse Model of CDKL5 Disorder Is Rescued by Insulin-like Growth Factor 1

Dendritic Spine Instability in a Mouse Model of CDKL5 Disorder Is Rescued by Insulin-like Growth Factor 1

Item
http://www.wikidata.org/entity/Q28268294
Insulin-Like Growth Factor 1 and Related Compounds in the Treatment of Childhood-Onset Neurodevelopmental DisordersA Subset of Autism-Associated Genes Regulate the Structural Stability of Neurons.Molecular and genetic insights into an infantile epileptic encephalopathy - CDKL5 disorder.Searching for biomarkers of CDKL5 disorder: early-onset visual impairment in CDKL5 mutant mice.Insulin-like Growth Factor 1 for Healthy Spines and Healthy Minds?Dysfunctional mTORC1 Signaling: A Convergent Mechanism between Syndromic and Nonsyndromic Forms of Autism Spectrum Disorder?Lack of Cdkl5 Disrupts the Organization of Excitatory and Inhibitory Synapses and Parvalbumin Interneurons in the Primary Visual Cortex.Mice lacking cyclin-dependent kinase-like 5 manifest autistic and ADHD-like behaviors.Diolistic Labeling and Analysis of Dendritic Spines.Loss of CDKL5 in Glutamatergic Neurons Disrupts Hippocampal Microcircuitry and Leads to Memory Impairment in Mice.The neurosteroid pregnenolone reverts microtubule derangement induced by the loss of a functional CDKL5-IQGAP1 complex.Comprehensive behavioral analysis of the Cdkl5 knockout mice revealed significant enhancement in anxiety- and fear-related behaviors and impairment in both acquisition and long-term retention of spatial reference memory.Heterozygous CDKL5 Knockout Female Mice Are a Valuable Animal Model for CDKL5 Disorder.
P2860

Dendritic Spine Instability in a Mouse Model of CDKL5 Disorder Is Rescued by Insulin-like Growth Factor 1

Item
http://www.wikidata.org/entity/Q28268294
description
2016 nî lūn-bûn
@nan
2016 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@ast
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@en
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@nl
type
label
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@ast
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@en
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@nl
prefLabel
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@ast
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@en
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P698
P921
P3181
P356
P1433
P1476
Dendritic Spine Instability in ...... y Insulin-like Growth Factor 1
@en
P2093
P304
P31
P3181
P356
10.1016/J.BIOPSYCH.2015.08.028
P407
P433
P478
P50
P577
P698
P921