Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases - Wikidata - awgldk - TriplyDB

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

http://www.wikidata.org/entity/Q28268392

about

Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family Identification of a novel human tankyrase through its interaction with the adaptor protein Grb14 Grb10 prevents Nedd4-mediated vascular endothelial growth factor receptor-2 degradation Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions Role for the adaptor protein Grb10 in the activation of Akt The adapter protein ZIP binds Grb14 and regulates its inhibitory action on insulin signaling by recruiting protein kinase Czeta Grb10, a positive, stimulatory signaling adapter in platelet-derived growth factor BB-, insulin-like growth factor I-, and insulin-mediated mitogenesis Solution structure of the human Grb14-SH2 domain and comparison with the structures of the human Grb7-SH2/erbB2 peptide complex and human Grb10-SH2 domain The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor Regulation of insulin and type 1 insulin-like growth factor signaling and action by the Grb10/14 and SH2B1/B2 adaptor proteins Association of fibroblast growth factor receptor 1 with the adaptor protein Grb14. Characterization of a new receptor binding partner Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family Localization of endogenous Grb10 to the mitochondria and its interaction with the mitochondrial-associated Raf-1 pool Evidence for an interaction between the insulin receptor and Grb7. A role for two of its binding domains, PIR and SH2 MEKK1 binds raf-1 and the ERK2 cascade components The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells mGrb10 interacts with Nedd4 Mek2 is dispensable for mouse growth and development The PIR domain of Grb14 is an intrinsically unstructured protein: implication in insulin signaling Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain.Tissue-specific regulation and function of Grb10 during growth and neuronal commitment.Using a phage display library to identify basic residues in A-Raf required to mediate binding to the Src homology 2 domains of the p85 subunit of phosphatidylinositol 3'-kinase.Inhibition of hGrb10 binding to the insulin receptor by functional domain-mediated oligomerization.Inhibition of insulin receptor catalytic activity by the molecular adapter Grb14.Ras-MAP kinase signaling pathways and control of cell proliferation: relevance to cancer therapy.Regulation of cytokine receptor signaling by SOCS1.Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism.Monoallelic loss of the imprinted gene Grb10 promotes tumor formation in irradiated Nf1+/- mice.Grb10 and Grb14: enigmatic regulators of insulin action--and more?Adapter protein connections: the MRL and Grb7 protein families.Backbone nuclear relaxation characteristics and calorimetric investigation of the human Grb7-SH2/erbB2 peptide complex Binding the atypical RA domain of Ste50p to the unfolded Opy2p cytoplasmic tail is essential for the high-osmolarity glycerol pathway.Direct binding of MEK1 and MEK2 to AKT induces Foxo1 phosphorylation, cellular migration and metastasis.Grb10 is a dual regulator of receptor tyrosine kinase signaling.Genetic and epigenetic abnormalities in systemic sclerosis.Grb10 is involved in BCR-ABL-positive leukemia in mice.FLT3 signals via the adapter protein Grb10 and overexpression of Grb10 leads to aberrant cell proliferation in acute myeloid leukemia

P2860

Q22011215-CBB6266C-29CD-442A-8649-A4C15D90DD31 Q24291017-DD7745CF-D25E-463E-9997-A74870A39E0A Q24323121-6A506355-4883-4571-9E47-9242BAC3C75A Q24532168-1CCCED3E-FD47-4B8C-955C-8EA2D8F08EE0 Q24537512-E1AA12B8-9A88-4147-83B2-E8DF6BA32152 Q24540143-6BD15535-AD66-4221-AA6B-5AF004493C6B Q24554440-0AE1D429-5723-47A4-A859-B2F6983C4199 Q24646307-5464866D-C5BF-4413-B12C-A784DC59E343 Q24682781-2AF00898-740A-46CA-9DCE-E1D0B22BC806 Q26849720-87BA9780-9F98-466C-96D2-67A86881D094 Q28138292-BF1F519F-776A-497F-BCC7-C2649F9C576D Q28139366-C9220CCD-5670-4501-B7C1-DCC3DB341AD4 Q28139493-ADA599FA-65E2-4734-AAD0-21D96440EC26 Q28143997-F6D063CE-19A0-4F24-904C-286579817B78 Q28145204-37AA7A98-18F6-4737-8304-687AABFDADC9 Q28199355-8BA6ED72-2257-4B81-998B-598970D2DAE5 Q28505191-6C9AFC4C-36A7-48F6-9AA1-2BB312939834 Q28505581-B05D6E7E-51A4-43FD-888A-9708E99583C1 Q28508597-6F081B80-0929-49A8-B80D-279773BC98BB Q28609344-71DF2307-9449-45FF-8504-77ACB62147A5 Q28909797-277CC758-979A-4146-8C3F-4A447BAF7D3B Q29417020-CF4777AC-572E-4282-BE51-16546212454C Q30157301-2DAA85DB-0801-4E82-A6AA-179F6E8D5DC6 Q30653788-FC43ED36-F34D-428D-BE91-5FAA5914B46F Q30914495-F74206E6-9007-4C74-A9DC-05967E6F81ED Q32058435-0E9DC367-055C-4739-849C-06217D7747D9 Q34103542-24FCDF2C-3812-4463-B22E-F6865723D9D8 Q34973413-8E5EFC5F-06F0-47D4-8E6B-625AA984D7B2 Q35096707-D755FC3F-EC81-4462-8321-D7A2BCDC280D Q35167917-C1616C0B-4D17-4DC4-9B17-77E55CD86E27 Q35639252-A0CCCD44-1EDE-4238-B21D-B3BDF207BA22 Q36131371-70D42B46-9044-42FE-83FF-44906C3016E5 Q36294476-F31B0B6A-2260-4BD3-9809-DC86ED61DAF2 Q36476851-7092D5A1-7DD4-46BE-931F-629FA832B63E Q37475318-EB160878-A535-4684-813C-FC1100FA8FB2 Q37657919-F0548B9C-58BB-4A6A-B7B7-F7351BDED66B Q38178194-DBD40F68-A8D1-4E8A-8104-33798837F9C8 Q38701980-E6D91AE2-BD33-48C1-994C-EDDE0D3A798E Q38953915-16F13267-4CAA-41AF-9B71-C72A42B72E02 Q39225058-35E12783-44C3-43B4-8803-B7072708FC08

P2860

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

http://www.wikidata.org/entity/Q28268392

description

1998 nî lūn-bûn

@nan

1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

1998年の論文

@ja

1998年論文

@yue

1998年論文

@zh-hant

1998年論文

@zh-hk

1998年論文

@zh-mo

1998年論文

@zh-tw

1998年论文

@wuu

name

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@ast

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@en

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@nl

type

label

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@ast

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@en

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@nl

prefLabel

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@ast

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@en

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@nl

P1433

Q28268392-E3782326-CB5D-48C8-89BA-754EC9B681C7

P1476

Q28268392-19115F6B-A4E7-4209-B0B4-E6BB008406C3

P2093

Q28268392-0A83F860-F8BD-4D32-91F2-3AA24CF382E7

Q28268392-3C1B111A-CB26-40A0-B7A8-D9D5AC37D222

Q28268392-7A5CE350-D309-471D-BB6D-8BA174639C03

Q28268392-E91B0139-5F46-403C-BBFD-E64048B9D491

P2860

Q28268392-027F3248-46DE-4B48-B217-F026E0ABE972

Q28268392-080AD94E-1127-4ED6-A5EB-5CA7C3EA4FA3

Q28268392-08B81E21-52F4-4658-BE19-78071A6FD08F

Q28268392-0BDDEBD1-F94D-45BD-BA4A-38C78615C0ED

Q28268392-0C021E38-0DF8-4378-AE08-F0CFAAED0B4A

Q28268392-116D4F0C-80B9-4AD1-892E-09F96B33228D

Q28268392-14D26D45-2839-44B5-9BF6-E8666EACA266

Q28268392-1A421E54-0C36-4536-BBA9-F77D5D76A2FA

Q28268392-1BFEA1E8-BFA8-41B6-81B6-ED054BA73BAC

Q28268392-2EE32734-3AC9-459D-98AF-7A786F1065AF

P304

Q28268392-45158B1A-2144-4814-9FBF-D74B45001E32

P31

Q28268392-C6888CEA-A181-4B89-96F5-004317DFA017

P356

Q28268392-5FD3B50E-A602-4BBB-A375-EDBD8D3A982F

P407

Q28268392-2E4E64B6-31D3-40DE-8705-88B135FD36EA

P433

Q28268392-861DC861-3A55-43E7-8A3F-4F429A348344

P478

Q28268392-22F13D11-5882-4BF1-9336-0B923B8483EB

P50

Q28268392-2B5E7C1A-4283-48A5-91B5-23BC65D1CB54

P577

Q28268392-D771E1A1-92C5-4A15-8B6C-8115AE1580AD

P5875

Q28268392-74EF91E7-A75E-4C34-9D77-60C4AB8E8475

P698

Q28268392-D529108A-1D06-40DE-AE0C-592CF754FED5

P356

JBC.273.17.10475

P1433

Journal of Biological Chemistry

P1476

Interaction of the Grb10 adapter protein with the Raf1 and MEK1 kinases

@en

P2093

A Nantel

http://www.w3.org/2001/XMLSchema#string

B I Posner

http://www.w3.org/2001/XMLSchema#string

J Sherk

http://www.w3.org/2001/XMLSchema#string

K Mohammad-Ali

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1

Structural determinants of the interaction between the erbB2 receptor and the Src homology 2 domain of Grb7

Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms

Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2

Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains

Molecular cloning of a phosphotyrosine-independent ligand of the p56lck SH2 domain

Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2

Ligand activation of ELK receptor tyrosine kinase promotes its association with Grb10 and Grb2 in vascular endothelial cells

SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1

Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors

P304

10475-10484

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1074/JBC.273.17.10475

http://www.w3.org/2001/XMLSchema#string

P407

P433

17

http://www.w3.org/2001/XMLSchema#string

P478

273

http://www.w3.org/2001/XMLSchema#string

P50

David Y. Thomas

P577

1998-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

51341778

http://www.w3.org/2001/XMLSchema#string

P698

9553107

http://www.w3.org/2001/XMLSchema#string