Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
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Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant miceMeta-analysis of SHANK Mutations in Autism Spectrum Disorders: a gradient of severity in cognitive impairmentsClinical and Neurobiological Relevance of Current Animal Models of Autism Spectrum Disorders.Striatal Circuits as a Common Node for Autism PathophysiologyMechanisms of Origin, Phenotypic Effects and Diagnostic Implications of Complex Chromosome RearrangementsBehavioral phenotypes of genetic mouse models of autism.Modeling psychiatric disorders for developing effective treatmentsSynaptic plasticity, neural circuits, and the emerging role of altered short-term information processing in schizophrenia.Therapeutic approaches for shankopathiesEnlarged dendritic spines and pronounced neophobia in mice lacking the PSD protein RICH2.Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice.Structure and function of neonatal social communication in a genetic mouse model of autismThe SocioBox: A Novel Paradigm to Assess Complex Social Recognition in Male Mice.Gender Dependent Evaluation of Autism like Behavior in Mice Exposed to Prenatal Zinc DeficiencyDysfunctional cerebellar Purkinje cells contribute to autism-like behaviour in Shank2-deficient mice.A Spontaneous Missense Mutation in Branched Chain Keto Acid Dehydrogenase Kinase in the Rat Affects Both the Central and Peripheral Nervous SystemsMutation of the CH1 Domain in the Histone Acetyltransferase CREBBP Results in Autism-Relevant Behaviors in MiceDeletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouseAbsence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.Genetic aspects of autism spectrum disorders: insights from animal modelsActin-Dependent Alterations of Dendritic Spine Morphology in ShankopathiesAdvancing the understanding of autism disease mechanisms through geneticsNeurobiology of social behavior abnormalities in autism and Williams syndromeSynaptopathies: synaptic dysfunction in neurological disorders - A review from students to studentsCommon mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disordersMice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.Mutations in BCKD-kinase lead to a potentially treatable form of autism with epilepsyAutism-associated gene Dlgap2 mutant mice demonstrate exacerbated aggressive behaviors and orbitofrontal cortex deficitsTranslational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.Lis1 controls dynamics of neuronal filopodia and spines to impact synaptogenesis and social behaviourShank3 deficiency induces NMDA receptor hypofunction via an actin-dependent mechanismAutism-related deficits via dysregulated eIF4E-dependent translational control.Recording Mouse Ultrasonic Vocalizations to Evaluate Social Communication.Social communication in mice--are there optimal cage conditions?The role of ultrasonic vocalizations in mouse communicationASD-relevant Animal Models of the Foxp Family of Transcription FactorsEngineered deafness reveals that mouse courtship vocalizations do not require auditory experience.Oxytocin improves behavioral and electrophysiological deficits in a novel Shank3-deficient ratZinc deficiency and low enterocyte zinc transporter expression in human patients with autism related mutations in SHANK3.
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P2860
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
description
2012 nî lūn-bûn
@nan
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@ast
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@en
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@nl
type
label
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@ast
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@en
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@nl
prefLabel
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@ast
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@en
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@nl
P2093
P2860
P50
P3181
P356
P1433
P1476
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2
@en
P2093
A Vanessa Stempel
A. Vanessa Stempel
Angelika Kuebler
Anna-Lena Janssen
Anne-Marie Le Sourd
Boris V Skryabin
Boris V. Skryabin
Claire S Leblond
Claire S. Leblond
Detlef Balschun
P2860
P2888
P304
P3181
P356
10.1038/NATURE11015
P407
P50
P577
2012-04-29T00:00:00Z
P5875
P6179
1020582984