Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma
about
Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytesThe hippo signaling pathway in development and cancerThe two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatmentHippo/YAP pathway for targeted therapyThe Hippo-YAP pathway in organ size control and tumorigenesis: an updated versionMerlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survivalhNaa10p contributes to tumorigenesis by facilitating DNMT1-mediated tumor suppressor gene silencingA crucial role of WW45 in developing epithelial tissues in the mouseCrucial role for Mst1 and Mst2 kinases in early embryonic development of the mouseSalvador-Warts-Hippo pathway in a developmental checkpoint monitoring helix-loop-helix proteins.The Hippo signaling pathway in stem cell biology and cancerThe role of the Hippo pathway in human disease and tumorigenesisLATS2 is de-methylated and overexpressed in nasopharyngeal carcinoma and predicts poor prognosis.Stability of the LATS2 tumor suppressor gene is regulated by tristetraprolinDown-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells.The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1Heat shock protein 90 inhibition depletes LATS1 and LATS2, two regulators of the mammalian hippo tumor suppressor pathway.Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected]Identification of a tumor suppressor relay between the FOXP3 and the Hippo pathways in breast and prostate cancers.A kinase shRNA screen links LATS2 and the pRB tumor suppressorNew genetic variants of LATS1 detected in urinary bladder and colon cancer.Lats2 modulates adipocyte proliferation and differentiation via hippo signaling.Yes-associated protein 1 is widely expressed in human brain tumors and promotes glioblastoma growth.NPHP4, a cilia-associated protein, negatively regulates the Hippo pathwayThe hippo pathway effector YAP regulates motility, invasion, and castration-resistant growth of prostate cancer cells.Down-regulation of LATS kinases alters p53 to promote cell migration.Decreased expression of LATS1 is correlated with the progression and prognosis of glioma.YAPing Hippo Forecasts a New Target for Lung Cancer Prevention and Treatment.Underexpression of LATS1 TSG in colorectal cancer is associated with promoter hypermethylationLoss of large tumor suppressor 1 promotes growth and metastasis of gastric cancer cells through upregulation of the YAP signalingEpigenetic changes in gliomas.Epigenetic markers in human gliomas: prospects for therapeutic intervention.Angiomotin stabilization by tankyrase inhibitors antagonizes constitutive TEAD-dependent transcription and proliferation of human tumor cells with Hippo pathway core component mutationsTranscriptional activation of the Lats1 tumor suppressor gene in tumors of CUX1 transgenic mice.Merlin is a potent inhibitor of glioma growthSilencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation.The pseudogene DUXAP10 promotes an aggressive phenotype through binding with LSD1 and repressing LATS2 and RRAD in non small cell lung cancer.Contribution of LATS1 and LATS2 promoter methylation in OSCC development.The Hippo pathway in biological control and cancer development.Mammalian Hippo pathway: from development to cancer and beyond.
P2860
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P2860
Promoter hypermethylation-mediated down-regulation of LATS1 and LATS2 in human astrocytoma
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@ast
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@en
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@nl
type
label
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@ast
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@en
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@nl
prefLabel
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@ast
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@en
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@nl
P2093
P3181
P1476
Promoter hypermethylation-medi ...... and LATS2 in human astrocytoma
@en
P2093
Xingang Li
Yuquan Jiang
Zheng Jiang
P3181
P356
10.1016/J.NEURES.2006.09.006
P407
P577
2006-12-01T00:00:00Z