Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk - Wikidata - awgldk - TriplyDB

Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk

Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk

http://www.wikidata.org/entity/Q28270295

about

Mnk kinase pathway: Cellular functions and biological outcomes The Structure of Eukaryotic Translation Initiation Factor-4E from Wheat Reveals a Novel Disulfide Bond Small-molecule p21-activated kinase inhibitor PF-3758309 is a potent inhibitor of oncogenic signaling and tumor growth PAK signalling during the development and progression of cancer Loss of MNK function sensitizes fibroblasts to serum-withdrawal induced apoptosis Initiation factor modifications in the preapoptotic phase.Phosphoprotein analysis: from proteins to proteomes Inhibition of Mitogen-activated Protein Kinase (MAPK)-interacting Kinase (MNK) Preferentially Affects Translation of mRNAs Containing Both a 5'-Terminal Cap and Hairpin.Pak protein kinases and their role in cancer.Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e.Anti-oncogenic potential of the eIF4E-binding proteins.PAK signaling in cancer.Stopped-flow kinetic analysis of eIF4E and phosphorylated eIF4E binding to cap analogs and capped oligoribonucleotides: evidence for a one-step binding mechanism.Regulation of eukaryotic initiation factor 4E (eIF4E) phosphorylation by mitogen-activated protein kinase occurs through modulation of Mnk1-eIF4G interaction.Inhibition of cap-dependent translation via phosphorylation of eIF4G by protein kinase Pak2 Features of the catalytic domains and C termini of the MAPK signal-integrating kinases Mnk1 and Mnk2 determine their differing activities and regulatory properties.Quantitative Phosphoproteomic Analysis Reveals Key Mechanisms of Cellular Proliferation in Liver Cancer Cells.Analysis of conformational changes during activation of protein kinase Pak2 by amide hydrogen/deuterium exchange.Stimulation of the cell death response by PAK-2p34 Mnk is a negative regulator of cap-dependent translation in Aplysia neurons.

P2860

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P2860

Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk

http://www.wikidata.org/entity/Q28270295

description

2004 nî lūn-bûn

@nan

2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2004年の論文

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2004年論文

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2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

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Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

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Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

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type

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Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

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Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

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Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

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Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

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Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

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Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

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P2860

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P1433

Journal of Biological Chemistry

P1476

Phosphorylation of Mnk1 by cas ...... interaction of eIF4G with Mnk

@en

P2093

Andrew J Waskiewicz

http://www.w3.org/2001/XMLSchema#string

Jolinda A Traugh

http://www.w3.org/2001/XMLSchema#string

Jonathan A Cooper

http://www.w3.org/2001/XMLSchema#string

Jun Ling

http://www.w3.org/2001/XMLSchema#string

Kevin C Orton

http://www.w3.org/2001/XMLSchema#string

Nadejda L Korneeva

http://www.w3.org/2001/XMLSchema#string

Robert E Rhoads

http://www.w3.org/2001/XMLSchema#string

William C Merrick

http://www.w3.org/2001/XMLSchema#string

P2860

Purification and characterization of a new eukaryotic protein translation factor. Eukaryotic initiation factor 4H

MNK1, a new MAP kinase-activated protein kinase, isolated by a novel expression screening method for identifying protein kinase substrates

Mitogen-activated protein kinases activate the serine/threonine kinases Mnk1 and Mnk2

Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E

The mitogen-activated protein kinase signal-integrating kinase Mnk2 is a eukaryotic initiation factor 4E kinase with high levels of basal activity in mammalian cells

Phosphorylation of the cap-binding protein eukaryotic translation initiation factor 4E by protein kinase Mnk1 in vivo

Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

Negative control of the Myc protein by the stress-responsive kinase Pak2

Phosphorylation of elongation factor 1 and ribosomal protein S6 by multipotential S6 kinase and insulin stimulation of translational elongation

P304

38649-57

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scholarly article

P356

10.1074/JBC.M407337200

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P433

37

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P478

279

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P50

Nahum Sonenberg

P577

2004-09-10T00:00:00Z

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P698

15234964

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P921

phosphorylation