Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas
about
Paternal uniparental disomy for chromosome 1 revealed by molecular analysis of a patient with pycnodysostosisRGS12 is essential for RANKL-evoked signaling for terminal differentiation of osteoclasts in vitroTGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and diseaseLarge scale isolation of osteoclast-specific genes by an improved method involving the preparation of a subtracted cDNA library.Specificity of RGS10A as a key component in the RANKL signaling mechanism for osteoclast differentiationThe silencing of cathepsin K used in gene therapy for periodontal disease reveals the role of cathepsin K in chronic infection and inflammation.Characterization of novel cathepsin K mutations in the pro and mature polypeptide regions causing pycnodysostosis.Human cathepsin W, a putative cysteine protease predominantly expressed in CD8+ T-lymphocytes.Novel pycnodysostosis mouse model uncovers cathepsin K function as a potential regulator of osteoclast apoptosis and senescenceTargeting Atp6v1c1 Prevents Inflammation and Bone Erosion Caused by Periodontitis and Reveals Its Critical Function in OsteoimmunologyRGS10-null mutation impairs osteoclast differentiation resulting from the loss of [Ca2+]i oscillation regulationSignaling networks that control the lineage commitment and differentiation of bone cells.Ac45 silencing mediated by AAV-sh-Ac45-RNAi prevents both bone loss and inflammation caused by periodontitis.Deficiency of cathepsin K prevents inflammation and bone erosion in rheumatoid arthritis and periodontitis and reveals its shared osteoimmune role.Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient miceCathepsin K, but not cathepsins B, L, or S, is abundantly expressed in human osteoclasts.C/EBPα regulates osteoclast lineage commitmentOsteoporosis - a current view of pharmacological prevention and treatmentEpidermal closure regulates histolysis during mammalian (Mus) digit regeneration.Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway.IL-1alpha stimulates cathepsin K expression in osteoclasts via the tyrosine kinase-NF-kappaB pathway.Effects of brefeldin-A: potent inhibitor of intracellular protein transport on ultrastructure and resorptive function of cultured osteoclasts.Expression of human cathepsin K in Pichia pastoris and preliminary crystallographic studies of an inhibitor complex.Inhibitory activity of Drynariae rhizoma extracts on cathepsin having bone resorption activity.CCAAT/Enhancer-binding Protein α (C/EBPα) Is Important for Osteoclast Differentiation and Activity.Quantification of the expression levels of lysosomal cysteine proteinases in purified human osteoclastic cells by competitive RT-PCR.Immunolocalization of vacuolar-type H+-ATPase, cathepsin K, matrix metalloproteinase-9, and receptor activator of NFkappaB ligand in odontoclasts during physiological root resorption of human deciduous teeth.Inhibition of osteoclast differentiation and bone resorption by cathepsin K antisense oligonucleotides.C/EBPα is Regulated by the RANK Cytoplasmic IVVY535-538 Motif and Stimulates Osteoclastogenesis more Strongly than c-Fos.Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development.Proteinase expression during differentiation of human osteoclasts in vitro.
P2860
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P2860
Cloning and complete coding sequence of a novel human cathepsin expressed in giant cells of osteoclastomas
description
1995 nî lūn-bûn
@nan
1995 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Cloning and complete coding se ...... giant cells of osteoclastomas
@ast
Cloning and complete coding se ...... giant cells of osteoclastomas
@en
Cloning and complete coding se ...... giant cells of osteoclastomas
@nl
type
label
Cloning and complete coding se ...... giant cells of osteoclastomas
@ast
Cloning and complete coding se ...... giant cells of osteoclastomas
@en
Cloning and complete coding se ...... giant cells of osteoclastomas
@nl
prefLabel
Cloning and complete coding se ...... giant cells of osteoclastomas
@ast
Cloning and complete coding se ...... giant cells of osteoclastomas
@en
Cloning and complete coding se ...... giant cells of osteoclastomas
@nl
P2093
P2860
P356
P1476
Cloning and complete coding se ...... giant cells of osteoclastomas
@en
P2093
A L Wucherpfennig
M Alexander
P Stashenko
P2860
P304
P356
10.1002/JBMR.5650100809
P407
P577
1995-08-01T00:00:00Z