The replicative regulator protein geminin on chromatin in the HeLa cell cycle
about
Two E3 ubiquitin ligases, SCF-Skp2 and DDB1-Cul4, target human Cdt1 for proteolysis.Selective killing of cancer cells by suppression of geminin activityAurora-A controls pre-replicative complex assembly and DNA replication by stabilizing geminin in mitosis.Geminin inhibits a late step in the formation of human pre-replicative complexes.Life without geminin.Geminin is required for the maintenance of pluripotency.Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways.Activation of a human chromosomal replication origin by protein tethering.Human CDT1 associates with CDC7 and recruits CDC45 to chromatin during S phase.Small-molecule mimics of an alpha-helix for efficient transport of proteins into cells.Preventing DNA over-replication: a Cdk perspective.Role of geminin: from normal control of DNA replication to cancer formation and progression?
P2860
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P2860
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@ast
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@en
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@nl
type
label
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@ast
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@en
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@nl
prefLabel
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@ast
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@en
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@nl
P356
P1476
The replicative regulator protein geminin on chromatin in the HeLa cell cycle
@en
P2093
Monika Kulartz
Rolf Knippers
P304
P356
10.1074/JBC.M405798200
P407
P577
2004-10-01T00:00:00Z